Antidepressant "Velaksin": ndidi testimonials, ntuziaka maka ojiji, analogs

Enwere m ike ịzụta antidepressants enweghị a ọgwụ? A ndepụta otú ahụ na ngwaahịa abụghị nnukwu. Nke a bụ n'ihi na eziokwu na ha nwere ike ịbụ na-eri ahụ, na a kpọrọ nke mmetụta. Ya mere, tupu ewere dị otú ahụ, jide n'aka na gaa na a ọkachamara.

ozi izugbe

Ịda mbà n'obi na-adịghị si ọgwụ ọjọọ. Ma ka mma ịrụ ọrụ nke ụjọ usoro, ọtụtụ ndị dọkịta ka ji nye iwu ka ha na-agwọ dị iche iche antidepressants. Otu n'ime ha bụ ọgwụ "Velaksin". Nleba banyere ngwá ọrụ a na ya atụmatụ na ntuziaka maka ojiji ga-ọkọnọ n'okpuru.

The mejupụtara nke ọgwụ, ya ụdị mmepụta

Na ihe n'ụdị na ọ na-arụpụta ihe antidepressant dị ka "Velaksin"? Mbadamba na capsules - bụ naanị forms nke ọgwụ.

Mbadamba "Velaksin"-acha ọcha, kanye na otu akụkụ "E741", na a okirikiri ewepụghị udi na chamfer. Ha n'ọrụ mgwa ihe bụ venlafaxine, nke na-anọchi anya n'ụdị a hydrochloride. Na-gụnyere na nke a ọgwụ na-agụnye inyeaka mmiri dị ka colloidal silica anhydrous, lactose monohydrate, sodium starch glycolate, magnesium stearate na MCC.

Juru n'ọnụ mbadamba ọnya Ukwu na katọn karị.

Drug "Velaksin" - capsules, ntuziaka maka ojiji nke na-nchọ na mkpo, akwụkwọ, gelatin na ihe siri ike. Ha nwere epe-aja aja okpu na a colorless mkpụrụ. N'ọrụ akụrụngwa nke a ụdị bụ nwekwara a compound venlafaxine. Ke adianade ya mejupụtara nke a ọgwụ na-agụnye ndị ọzọ Efrata.

Dị ka ọgwụ ọrụ?

"Velaksin" - a ọgbọ ọhụrụ nke mgbochi depressant. Dị ka chemical Ọdịdị nke ya-arụsi ọrụ umi-abụghị nke ọ bụla mara na klas nke antidepressants (e.g., tricyclic, tetracyclic, ma ọ bụ ndị ọzọ). Ọkachamara na-ekwu na ọgwụ bụ ọrụ enantiomer 2 racemate.

Ụkpụrụ nke ihe nke a ọgwụ na-metụtara ya ike potentiate na CNS akwara foosu nnyefe.

Dị ka ntụziaka, venlafaxine na ya bụ isi metabolite (EFA ma ọ bụ O-desmetilvenlafaksin) na-anọchi anya nwere ike inhibitors nke reuptake nke nọrepinefrini na serotonin na-adịghị ike inhibitors nke dopamine reuptake. Anyị nwere ike ikwu na ndị a bekee nwere ike belata beta-adrenergic ọrụ mgbe a otu na mgbe nile na-ọgwụ. EFA na venlafaxine bụ dokwara irè megide reuptake nke neurotransmitters.

Olee ihe ọzọ dị ịrịba ama iji ọgwụ "Velaksin"? Guide na-akọ na ndị nọ n'ọrụ mgwa nke ọgwụ nwere ihe mmekọrita ya na ndị n- na m-cholinergic anabata, ụbụrụ α1-adrenoceptors na histamine H1-anabata. Ọzọkwa, ọ na-egbochi ihe nke Mao na ọ dịghị ihe myirịta na fentsiklidinovymi, opioid, benzodiazepine na NMDA-anabata.

The kinetics nke ọgwụ

ma ọgwụ na-etinye obi gị dum, "Velaksin" (mbadamba)? Ntuziaka maka Iji na-ekwu na-arụsi ọrụ ike akụrụngwa nke a ọgwụ na-nnọọ nke ọma etinye obi gị dum na gootu. Mgbe a otu dose of agwọ ọrịa na a onunu ogwu nke 25-150 mg nke ya kasị elu ịta na ọbara ruru mgbe 2.4 awa. N'ihi ya venlafaxine na-ọtụtụ metabolized ke akpa ngafe site imeju. Ọ bụrụ na ọgwụ a na-e nri, mgbe ya elu ịta-abawanye site na 27-30 nkeji na plasma.

Isi metabolite a na-ewere a n'aka O-desmetilvenlafaksin. Ya ọkara-ndụ na mmechi ọkara ndụ nke venlafaxine bụ 11 na 5 awa, karị (mmepụta na-agbanweghi agbanwe ụdị site na akụrụ).

The kinetics ọgwụ ọjọọ eme ihe pụrụ iche na-adakarị ọnọdụ

Drug "Velaksin" ntụziaka a chọrọ ọgụgụ na ndị mmadụ na-imeju nke imeju nwere ndị ọzọ kinetic atụmatụ. ọbara ịta nke ọgwụ mụbara na ndị a ọrịa, na ya ọnụego nke excretion, on Kama nke ahụ, belata.

Na oké gbasara akụrụ insufficiency, gbasara akụrụ odida na-agafeghị oke ngụkọta nwechapụ EFA na venlafaxine na-ebelata na iwepụ ọkara ndụ oge na-lengthened.

Ọ kwesịkwara kwuru na okike na afọ nke ọrịa anaghị emetụta pharmacokinetics nke ọgwụ na-atụle.

egosi maka

Gịnị mere anyị mkpa a ngwá ọrụ ndị dị ka "Velaksin"? The ojiji nke a ọgwụ e gosiri na ịda mbà n'obi nke dị iche iche si malite (maka ọgwụgwọ na prophylaxis).

Bans nhọpụta

N'okpuru ihe ọnọdụ nwere ike iji ọgwụ ọjọọ "Velaksin"? Nyocha nke ọrịa na dọkịta na-ekwu na a ọgwụ na-contraindicated na-enweta:

• mgbe na-anata Mao inhibitors ;
• na oké akụrụ ọrịa;
• n'oge a-enyo enyo ma ọ bụ ike ime;
• na oké ọrịa imeju;
• n'oge ara;
• na-eto eto na nke nwata, ya bụ, ruo mgbe afọ nke ọtụtụ;
• na elu uche ọgwụ ahụ.

Ọzọkwa, a ọgwụ ga-ọma weere na-ejighị n'aka rịaworo, myocardial infarction (gụnyere ọhụrụ kwagara), ọbara mgbali elu, ụfụ ihe mere eme, tachycardia, arọ ọnwụ, mụbara intraocular nsogbu, n'akuku-mmechi glaucoma, pụrụ ịrịa ọbara na-agba site na mucous na anụ ahụ, manic ekwu.

Drug "Velaksin" (mbadamba): ntuziaka maka ojiji

Antidepressant "Velaksin" kwesịrị naanị iwere n'oge nri. The na-atụ aro amalite dose nke ọgwụ bụ 75 mg, kewara na 2 kewara doses (i.e., 37,5 mg ugboro abụọ n'ụbọchị), kwa ụbọchị.

Ọ bụrụ na mgbe ọtụtụ izu nke ọrịa, ọrịa na-arịa dịghị mma, kwa ụbọchị dose na-ụba 150 mg a ụbọchị, na abụọ kewara doses (i.e., 75 mg ugboro abụọ n'ụbọchị).

Ọ bụrụ na onye ọrịa na-achọ a elu dose of ihe antidepressant (e.g., isi dara ya mbà aghara, ma ọ bụ ndị ọzọ ọnọdụ ndị chọrọ ọgwụ anyịnya), mgbe ahụ ọkachamara nwere ike ikpo 150 mg nke ọgwụ na 2 awa, na mgbe ahụ na-eji nwayọọ nwayọọ dịkwuo dose 75 mg (2-3 ụbọchị gasịrị) iji nweta ihe ndị ha chọrọ N'ihi.

Dị ka ntụziaka, karịa onunu ogwu "Velaksina" bụ 375 mg kwa ụbọchị. Mgbe o rusịrị ezi mmetụta, ọ nwere ike jiri nwayọọ nwayọọ zie na kacha nta ozo.

Nlọghachi azụ mgbochi na mmezi ọgwụ

Aka na-elekọta ego nwere ike na-site na ọnwa isii. Na nke a, na ọgwụ na e ke ntakiri doses.

Na nwayọọ gbasara akụrụ insufficiency mgbazi dosing Usoro a chọrọ. Na a yiri ọrịa agafeghị oke dose-atụ aro ala site 25-50%. Ọ kwesịkwara kwuru na venlafaxine ghara ga-eji na oké gbasara akụrụ insufficiency, ebe enweghị ihe ọmụma banyere nchekwa nke ndị dị otú ahụ ọgwụ ka ụbọchị, ọ dịghị.

Ndị na-na hemodialysis, kwesịrị ịnata 50% nke mbụ kwa onunu ogwu nke ọgwụ mgbe nnọkọ na nsọtụ.

N'ihi nwayọọ hepatic insufficiency mgbazi dosing Usoro a na-adịghị chọrọ. Mgbe ọrịa na-agafeghị oke dose ga-belata 50%. Banyere oké hepatic ọdịda, na nke a na ojiji nke venlafaxine ajuru aju.

Ndị agadi, na ọgwụ "Velaksin" ga-eji na oké ịkpachara anya. Nke a bụ n'ihi na o kwere omume mmebi nke na akụrụ ya. The ọrịa ga-nye iwu kasị ala irè dose. Na nke a, ọrịa kwesịrị n'okpuru mgbe nile nlekọta nke ndị ọrụ.

kagbuo antidepressant

N'elu ẹkụre nke na-anata ọgwụ ga-atụle iji belata dose nwayọọ nwayọọ (n'ime otu izu). Ọ na-achọrọ na-edebe ọnọdụ onye ọrịa, iji belata ihe ize ndụ nke oghom Jeremaya mere metụtara na-ekpochapụ nke ọgwụ.

Oge a chọrọ maka zuru cessation nke ọgwụ, na-adabere na onunu ogwu, oge nke ọgwụ na mmadụ n'otu n'otu.

mmetụta

Gịnị bụ achọghị mmetụta nke ọgwụ nwere ike ime ka "Velaksin"? Nleba na-ekwu na mmepe nke ndị ma ọ bụ ndị ọzọ oghom ihe na-esonụ iji ngwá ọrụ a na-adabere na dose natara.

Ndị kasị Ugboro Jeremaya mere Egosipụta ọjọọ ọdịdị na-agụnye ndị na-esonụ:

• ọbara mgbali elu, na-ebelata agụụ, ndiiche nrọ, afọ ntachi, ehighi ura, ọgbụgbọ, flushing nke anụ ahụ, mara jijiji, vomiting, muscle cramps, akọrọ ọnụ;
• ịmụ anya arọ nrọ, ịba ọcha n'anya, na arọ ọnwụ, tachycardia, hyponatremia, enweghị mmasị, postural hypotension, dizziness, manic mmeghachi omume, ụjọ excitability, yawning, paresthesia, neuroleptic syndrome, stupor, serotonergic syndrome;
• ụba Akwara ụda, ọdụdọ, dysuria, photosensitivity, urinary njigide, anorgasmia;
• agba ọbara na anụ ahụ, ndiiche ejaculation, menorrhagia, ebelata libido, sweating;
• thrombocytopenia, ulo n'ọgba aghara, erythema multiforme, mydriasis, Stevens - Johnson, visual n'ọgba aghara, mkpọchị uto, prolongation nke na-agba ọbara oge, adịghị ike, anụ ọkụ ọkụ, ike ọgwụgwụ, anaphylactic Jeremaya mere.

Ọ kwesịkwara kwuru na mgbe mberede ndọrọ ego nke na-atụle ụgbọala ma ọ bụ belata ya onunu ogwu kwere omume dị otú ahụ n'akụkụ Jeremaya mere ka ụjọ ogwe, ike ọgwụgwụ, afọ ọsịsa, iro ụra, erughị ala, isi ọwụwa, paraesthesias, ọgbụgbọ, hypomania, vomiting, sweating, anorexia, ehighi ura, akọrọ ọnụ, nchegbu, dizziness na mgbagwoju anya. A, ndị a mgbaàmà dị nwayọọ ma na pụọ enweghị usoro ọgwụgwọ ọ bụla.

na-atụ aro

Ere ma antidepressants enweghị a ọgwụ? A ndepụta ọgwụ ndị a bụ nnọọ nnukwu ( "Prozac", "Paxil", "Despres", "Azafen", "Persian", "amitriptyline"), na ọgwụ ọjọọ, "Velaksin" na-adịghị gụnyere ya. Ịzụta ya na pharmacies, ị nwere ike naanị site ndenye ọgwụ nke dọkịta.

Tupu ewere a ọgwụ n'okpuru nyochaa, karịsịa ọrịa na dara ya mbà ọrịa, a ga-atụle a elu puru nke igbu onwe mgbalị. Na nke a, na mmalite nke usoro ọgwụ na-atụ aro maka ke kacha nta dose na n'okpuru nso ọgwụ na ahụ ike na-elekọta.

Ndị na- ọrịa uche n'oge ọgwụgwọ na antidepressants nwere ike ịzụlite manic ma ọ bụ hypomanic ala.

Ọrịa kwesịrị ijide n'aka na adọ aka ná ntị banyere mkpa ọ ozugbo ahụ a dọkịta bụrụ na nke urticaria ọcha, rashes ma ọ bụ nfụkasị Jeremaya.

Ụfọdụ ọrịa na usoro nke na-anata venlafaxine hụrụ a dose-ndabere na-abawanye na ọbara mgbali.

Agadi ọrịa a ga-dọrọ aka ná ntị nke a kwe omume mebiri nke echiche nke itule na dizziness development.

N'oge ọgwụgwọ nke ego kwesịrị izere iwere mmịn.

Antidepressant "Velaksin": ndidi testimonials, ngwaahịa analogues

Ihe ndị mmadụ na-ekwu banyere nke a ọgwụ ka a ndidi? Ọtụtụ na-eji ọkụ kọrọ a ọnụ ọgụgụ buru ibu nke mmetụta na-erukwa na mgbe na-ewere nke a ọgwụ. Ọtụtụ mgbe a ọgwụ na-akpata oghom Jeremaya mere dị ka iro ụra, adịghị ike, ehighị ụra nke ọma, ọdụdọ, ndiiche echiche, ịda mbà n'obi na mgbagwoju anya. Ke adianade do, ụfọdụ ọrịa na-ekwu na ihe ndị a anọgide na mgbe ẹkụre ọgwụgwọ. Ọzọkwa, ọtụtụ ọrụ mkpesa banyere ọdịdị ịkwụsị ịṅụ na na nduzi.

Gịnị nwere ike dochie antidepressant dị ka "Velaksin"? Analogs nke a ọgwụ na-na-agaghị ahụ na niile drugstores. Dị ka a na-achị, ndị ọkachamara a na-agụnye ndị na-esonụ: "Venlafaxine Sandoz", "Efevelon", "Alvent", "Nyuvelong", "Velafaks", "Dapfiks", "Voksemel", "Venlaksor", "Vensuert", "venlafaxine".