"Azathioprine": analogues, price, ndu na reviews

Autoimmune ọrịa - a ìgwè nke enweghị nchịkwa ọnọdụ nke e nwere mụbara ọrụ nke dịghịzi usoro megide ahụ nke ya. Iji belata dịghịzi nzaghachi, kenyere ọgwụ ndị na-ebelata dịghịzi usoro. Otu a ọgwụ ọjọọ eme ihe dị oké mkpa na transplantation iji gbochie aka jụrụ. Ka anyị lee otú ahụ a ọgwụ, dị ka a "Azathioprine" analogs nke ọgwụ, na ntuziaka maka ojiji nke ya atụmatụ.

pharmacological akparamagwa

-Ya nke ọgwụ "Azathioprine" e nwere n'ọrụ mgwa nke otu aha. Nke a chemical compound bụ a emepụta nke bekee mkpa maka njikọ nke DNA na RNA. Ke idem, azathioprine enye DNA njikọ na, mmọdo, egbochi cell nkewa Filiks ke arọ. Mbenata ọrụ nke dịghịzi usoro mere site mmetụta nke ọgwụ ọjọọ, "Azathioprine" na lymphoid anụ ahụ.

N'ihi ya, ọ mgbochi nke cell nkewa Filiks na cellular dịghịzi omume. Mgbe iwebata "Azathioprine" nkwadebe na ahụ bụ ndiiche Mbelata na ọnụ ọgụgụ nke phagocytes ma belata immunoglobulin njikọ. Ka anyị ọzọ inyocha ihe ọmụma: ihe bụ àgwà nke "Azathioprine" ọgwụ analogues, price, ntuziaka maka ojiji.

Pharmacokinetics

The ọgwụ na-nnọọ rụọ ọrụ nke ọma etinye obi gị dum n'ime systemic mgbasa, na ya kacha ịta hụrụ mgbe naanị 2 awa mgbe onu ochichi. The ọgwụ bụghị karịsịa ụzọ ụkwụ na plasma-edozi: ya nkịtị ka ha ruo 30%. N'ihi azathioprine e ji mara mmetụta isi metabolic ma ọ bụ mbụ ngafe site imeju.

Agafe hepatocytes, ọgwụ na-metabolized na-arụsi ọrụ ike compound - mercaptopurine, na nke nwere pharmacodynamic mmetụta. Nwa fọrọ nke nta kpamkpam anyụpụ na bile. The mmamịrị anyụpụ site ọ dịghị ihe karịrị 2% nke agwọ ọrịa.

egosi

Nkwadebe "Azathioprine" analogues na otu nọ n'ọrụ umi na-gosiri maka ojiji na transplantation iji gbochie aka jụrụ mmeghachi omume.

Ọzọkwa, ọgwụ na-irè eji na rheumatological omume na-emeso ọrịa ogbu ogbu na nkwonkwo na autoimmune ọrịa ndị dị ka ịba ọcha n'anya, systemic lupus erythematosus, psoriasis, thrombocytopenic purpura, pemphigus, na ọtụtụ ndị ọzọ.

contraindications

Drug "Azathioprine" na-contraindicated na ọrịa na hypersensitivity ọgwụ akụrụngwa. N'ihi na eziokwu na ọgwụ na-egbochi niile germs ọbara, "Azathioprine" na-contraindicated na ọrịa na nke ọbara (anaemia leykotsito- na lymphopenia, thrombocytopenia), nakwa dị ka ime na nwa ara na.

Jiri n'oge ime na ara

N'ọrụ umi-aga n'ime mmiri ara na site gematoplatsentarny mgbochi. Na nke a, na iji na-adịghị atụ aro na ime na ara. Ọ bụrụ na ọ dị mkpa, nhọpụta nke ọgwụ ma ọ bụ ya analogues a, Atiya nke mmadụ dị mkpa na-amata ihe ize ndụ site na iji ihe na ojiji nke ọgwụ ọjọọ na ndị nwere nsogbu nye nne na nwa ebu n'afọ. Mgbe na-ekenye mmadụ n'oge ara nso nso iji kagbuo.

Atụmatụ nke ngwa

The ọgwụ na ya analogs mkpa na-eji na ịkpachara anya na ọrịa na-ata ahụhụ site na chikinpoksi, na ọrịa na erughi nke xanthine oxidase.

mmetụta

The isi otu nke mmetụta jikọtara mgbochi nke ụmị ọkpụkpụ ọrụ, maka mmepụta nke mkpụrụ ndụ ọbara uhie. N'itinye analogs nwere azathioprine, onye na-abawanye na size nke mkpụrụ ndụ na ọbara, Mbelata leucocyte ọnụ, platelet ọnụ, anaemia.

N'ihi na akụkụ nke digestive tract kasị nkịtị mmetụta na-agụnye: ebelata agụụ, stool ọrịa, mkpọchị hepatic ọrụ, ọnyá ọnya nke eriri afọ tract. Ekwe Omume ọnwụ nke hepatocytes, sochiri na-abawanye na bilirubin ma ọ bụ ndị ọzọ imeju ọrụ ule. Na ọrịa emume ịwa ahụ maka ngwa transplants na anụ ahụ nwere ike ịzụlite pancreatitis, ọnyá ọnya nke afo, eriri afọ, mmepe nke na-egbu egbu ịba ọcha n'anya.

Nfụkasị Jeremaya ime nnọọ adịkarịghị mgbe ndinọ ọgwụ ọjọọ, "Azathioprine" analogs dabeere na ya (e.g., "Azathioprine"). Ngosipụta bụghị kwuru na, tumadi ruru ka akpụkpọ ọkụ ọkụ ma ọ bụ feverish ekwu.

Tinyere ihe ndị ọzọ mmetụta ga-kwuru na mmepe nke abụọ na-efe efe Filiks ke idem, ọdịdị muscular na nkwonkwo mgbu, nnukwu gbasara akụrụ ọtọ insufficiency. Na ụfọdụ oké ikpe, ndị ọgwụ ọjọọ, "Azathioprine" analogues na otu nọ n'ọrụ umi nwere ike ime ka hemolytic anaemia, na-enye ihe mgbaàmà si Central ụjọ usoro. Azathioprine ka a pharmaceutically ifịk umi, a akụkụ nke otu aha ọgwụ ọjọọ na ya analogues, nwere a akpọ mmetụta na nwa ebu n'afọ (teratogenic na mutagenic mmetụta) na ike nke na-akpali iche ọdịdị akpụ Filiks ma na ha ụdi malignancy. N'ihi ya, ọ dị mkpa na-enyocha oru nke ọgwụ "Azathioprine" (mbadamba) reviews, nkọwa, ọgwụ analogues na-ahọrọ nri si eme. N'ileghachi anya n'ihu, anyị na-arịba ama na dị ka nọ n'ọrụ mgwa azathioprine akpa mmetụta bara uru na N'ezie nke ọrịa, dị ka ndị na-egosi. Nke a gosiri bụghị nanị dọkịta ma ọrịa onwe ha.

"Azathioprine" - synonyms, analogs

Azathioprine - pụrụ iche na ya onwe ha ụzọ a umi nwere immunosuppressive edinam. Na echiche nke ọgwụ ahịa bụghị nnọọ nke ọma na-anọchi anya preparations nwere azathioprine. Analogs "azathioprine" nwere ike ọkọnọ na ndị dị otú a ọgwụ, dị ka a "Azathioprine".

The ọgwụ dị na mbadamba ụdị na yiri ọdịnaya azathioprine. The naanị nuance bụ ndị na-eri "Azathioprine" nke ọgwụ, nke nwere ike na 4-5 ugboro na-eri nke "azathioprine" Russian mmepụta.

Nsi na ovadozu

Drug ovadozu "Azathioprine" na ya counterpart "Azathioprine" gosipụtara ọrịa nke eriri afọ tract, suppression nke ụmị ọkpụkpụ ọrụ, nakwa dị ka ụba imeju ọrụ ule. nsi ọgwụgwọ dị ka ọgwụ onwe ya na ya analogues bụ symptomatic, iji na-awụ ọsọ mkpochapu ọgwụ si ahụ. Ọ dịghị kpọmkwem ngwọta. Dialysis detoxification ụzọ ndị dị irè na akụkụ n'ihi n'ọrụ umi site na ha anyụpụ kpam kpam.

adọ aka ná ntị

The ọgwụ na ya analogs na-atụ aro n'ihi na ogologo oge. Ná mmalite nke ọgwụgwọ na-achọ mgbe nile na nlekota nke mkpụrụ ndụ nke elu ọbara, nakwa dị ka nlekota nke imeju enzymes.

N'ọdịnihu, kwa ụbọchị akara nke na-esi ahapụ, na-eduzi nlekota ọmụmụ ugboro ma ọ bụ ugboro abụọ a ọnwa.

ọgwụgwụ

The ọgwụ na ya analogs nwere ike ikpo na ahụmahụ ọkachamara. Tupu ewere n'aka na ọ dị mkpa na-ata a full nnyocha na ikekwe na-eduzi mmezi ọgwụ. Maka ozi ọzọ, na-enyere nhọpụta nke "Azathioprine" nkwadebe ntuziaka maka ojiji. Price, analogues nke ngwá ọrụ a dị ka akụkụ nke a-efegharị efegharị nke ọrịa. N'ihi ya, nke kacha nta na-eri nke 50 mbadamba bụ na mpaghara nke 250-300 rubles, na banyere analogues kwuru n'elu. Tupu ewere gị aghaghị ịtụle "Uru" na "cons" na-amalite usoro ọgwụgwọ.