Drug "Sibutin": ntuziaka maka ojiji, nkọwa na reviews

Mgbe na otú onye ọrịa na-kenyere ọgwụ "Sibutin"? Ntuziaka maka ojiji, n'ezie na ogbo na-egosi maka ojiji ọkọnọ obere n'ihu. The isiokwu na-atụle ihe ndị mejupụtara nke ọgwụ, ya ụdị na ntọhapụ mgbochi maka ojiji.

Udi, nkọwa na mejupụtara

Nkwadebe "Sibutin", ntuziaka maka ojiji nke a na-egosi n'okpuru, na-emepụta na ụdị ọcha gburugburu mbadamba na akara na otu akụkụ. Ha nọ n'ọrụ umi bụ oxybutynin (n'ụdị nke oxybutynin hydrochloride). Ọzọkwa na agwọ ọrịa na-agụnye adjunct Efrata, dị ka n'ụdị lactose monohydrate, microcrystalline cellulose, nduku starch na calcium stearate.

Pharmacological Njirimara nke ọgwụ

Olee otú "Sibutin"? Ntuziaka maka ojiji, ezigbo dọkịta na-akọ na ndị usoro nke ihe nke a ọgwụ bụ kpamkpam n'ihi na arụmọrụ nke ya-arụsi ọrụ bekee.

Dị ka ndị ọkachamara, "Sibutin" na-anọchi anya blocker M-cholinergic anabata, nke ìgwè nke tertiary amines. Na echiche nke M-agafeghị oke anticholinergic ọrụ, isiokwu gị n'ụlọnga bụ ike nke na-emetụta kpọmkwem na-eji ire ụtọ mọzụlụ nke viscera. N'otu oge ahụ na ọ nwere antispasmodic na myotropic edinam. Ndị ọzọ okwu, a ọgwụ eliminates apịajighị apịaji, na ebelata Akwara ụda ndị na-esonụ aru: na biliary tract, eriri afọ tract, urinary tract, akpanwa na eriri afo. Ọ ga-iburu n'uche na na ndị mmadụ na neurogenic dysfunction ikpeazụ oxybutynin bụ ike iji zuru ike na detrusor, iji belata ya n'amaghi contractions, belata ugboro nke urination, nakwa dị ka dịkwuo ike nke eriri afo.

Kinetics nke ọgwụ

Etinye obi gị dum ọnụ ma dị otú ahụ dị ka "Sibutin"? Ntuziaka maka ojiji (akụkụ nke ọgwụ e depụtara n'elu) na-akọ na mgbe ojiji nke oxybutynin mbadamba pụtara ngwa ngwa etinye obi gị dum na digestive tract.

Studies gosiri na kacha ịta nke mmewere na na ọbara ya bụ banyere 8-13 and / ml. Nke a na ọnụ ọgụgụ a na-ahụkarị maka Dosages nke 7-10 mg adiaha-eto eto na ike ndị mmadụ n'otu n'otu. Ọzọkwa, e nwere ndị dị ịrịba ama na onye mgbanwe ego nke oxybutynin na plasma.

Na echiche nke mbụ Itie site imeju, ndị zuru systemic bioavailability nke umi bụ banyere 6.2%.

Isi metabolite nke oxybutynin bụ ọrụ desethyloxybutynin. Ọzọkwa guzobere mgbanwe usoro, na ndị ọzọ nkwekọrịta tinyere feniltsiklogeksiglikolevaya acid, Otú ọ dị, ha na-adịghị ejekwa ozi.

About 0,02% natara agwọ ọrịa na-tọhapụrụ na mmamịrị. Communication oxybutynin ka albumin bụ banyere 83-86%, na oge nke ya ọkara ndụ bụ awa abụọ.

Ruo ogologo oge iji ọgwụ ya ìgwè bụ ala.

Egosi maka ojiji nke ọgwụ

Mgbe onye ọrịa ahụ nwere ike e kenyere "Sibutin"? Ntuziaka maka ojiji (egosi ga-atụle n'okpuru), ọ na-enye na ọgwụ na ọtụtụ-eji na ọgwụgwọ nke urinary incontinence n'ihi ejighị n'aka ọrụ nke eriri afo, nke bụ nke neurogenic uwa (e.g., detrusor hyperreflexia, spina n'ọkpụkpụ azụ m ma ọ bụ multiple sclerosis) ma ọ bụ nwere mgbawa okike.

Ọ kwesịkwara kwuru na ndị a n'aka ike na-egosi maka nocturnal enuresis na ụmụ noo afọ ise. N'ihi nzube a ka agwọ ọrịa na-eji na monotherapy, na na Nchikota na ọgwụ ndị ọzọ.

Ukpan iji ihe mbadamba

Mgbe bụghị ndinọ onye ọrịa ọgwụ "Sibutin"? Ntuziaka maka Iji na-ekwu na contraindications inweta a ọgwụ na-na-esonụ na-ekwu:

• bowel mgbochi;
• Hypersensitivity ka n'aka mmiri;
• nsia atony;
• kwuru ọrịa hazie eruba mmamịrị si eriri afo;
• myasthenia gravis;
• ọnyá afọ (oké);
• mmụba nke colon;
• ime;
• glaucoma;
• ara;
• afọ ise.

Drug "Sibutin": ntuziaka maka ojiji

Mbadamba "Sibutin" ndinọ ukwuu n'ime ndị okenye. Ha ga-ewere 5 mg ugboro atọ n'ụbọchị. Agadi ọrịa ifịk ọgwụ na-atụ aro iji ke ichekwa 5 mg ugboro abụọ n'ụbọchị.

Na pụrụ iche ikpe, a na nkà mmụta ọgwụ na-ndinọ ka ụmụaka na-erubeghị afọ ise na afọ. Mebiri nke eriri afo neurogenic ọdịdị nke iji ọgwụ ọjọọ eme site 5 mg ugboro abụọ n'ụbọchị, na n'abalị enuresis - 5 mg ugboro atọ n'ụbọchị. Na nke a, ndị ikpeazụ dose kwesịrị iwere nri tupu alakpu ụra.

mmetụta

Gịnị bụ mmeghachi omume nke a na-adịghị mma agwa bụ a na nkà mmụta ọgwụ "Sibutin"? Ntuziaka maka ojiji na-akọ na ọtụtụ n'ime ndị a na mmetụta na-ebilite na akụkụ nke digestive tract. Dị ka a na-achị, ha na-egosi akọrọ ọnụ, afọ ntachi, ọgbụgbọ, abdominal erughị ala na afọ ọsịsa.

-Atụle ọgwụ nwere ike ime ka:

• isi ọwụwa, bịara ikiri ọhụụ, iro ụra, dilated ụmụ akwụkwọ, dizziness, mụbara intraocular mgbali;
• akọrọ akpụkpọ;
• tides (ime tumadi na umu), urinary njigide, ike nwoke, arrhythmia, belata igba ajirija.

ikpe nke ovadozu

Gịnị mgbaàmà ime mgbe ọgwụ ovadozu "Sibutin"? Ntuziaka na ngwa na-ekwu na ndị dị otú ahụ bụ ngosipụta na-agụnye ndị na-esonụ: nchegbu, mụbara ogo oghom Jeremaya mere, n'ahụhụ, akụkụ okuku ume na nrugharị ọbara ọdịda, ala ọbara mgbali, psychosis, atụbọ ma mkpọnwụ nke akụkụ okuku ume na akwara.

Maka ọgwụgwọ nke ọnọdụ ndị dị otú itinye gastric lavage, nakwa dị ka igba ogwu n'akwara ochichi nke physostigmine.

Mgbe kwuru excitation ma ọ bụ nchegbu ọrịa ndinọ "Diazepam" (w / w, 10 mg) na fever symptomatic ọgwụ, tachycardia egosi nkwadebe "propranolol" (w / w) na urinary njigide rụrụ catheterization nke eriri afo, mgbe mkpọnwụ nke akụkụ okuku ume uru na mmepe kurarepodobnymi mmetụta enye ventilashion.

Olee otú ọ na interacts na ndị ọzọ ọgwụ ọjọọ eme ihe?

Enwere m ike iji ọzọ n'aka nkwadebe "Sibutin"? Ntuziaka na ngwa nke na-ekwu, nke mgbe jikọtara ndị ọzọ ọgwụ ọjọọ eme ihe na-ewere a na nkà mmụta ọgwụ nwere ike ime ka ụba n'akụkụ Jeremaya mere. A, mmetụta dị otú ahụ na-ahụ kwuru mgbe inweta "Sibutina" na mmadụ na-enwe ihe anticholinergic edinam.

Ogwuura ọgwụ ọjọọ na ethanol nwere ike na-eme ka dizziness na iro ụra ikowa.

Ọnụ na mbanye "itraconazole" oxybutynin enwekwu ịta ke iyịp.

n'oge ime

Ọ ga-ekwe omume n'oge nke nwa na-eche ka na-eji ọgwụ na ajụjụ? Safety na-eji "Sibutina" bụghị e guzosie ike mgbe oge a. Ya mere, nke a udi nke ọrịa, kwuru, sị pụtara bụghị họpụtara. Ọ kwesịkwara kwuru na oxybutynin nwere ike gafee n'ime mmiri ara, Ya mere ọ na-ekwesịghị-eji n'oge lactation. Ọ bụrụ na ọ ka dị mkpa, ara ga-kwụsịrị.

Specific ọmụma

Gịnị mkpa ka ị mara onye ọrịa n'ihu iji a na nkà mmụta ọgwụ "Sibutin"? Ntuziaka maka ojiji (analogues depụtara n'okpuru ebe) na-ekwu na ihe ókè ịkpachara anya ọgwụ ga-ndinọ mkpọchị agadi ọrịa, na ọrịa na oké ọrịa nke akụrụ na umeji neuro dystonia.

Dị nnọọ ka ndị ọzọ na anticholinergics, na ngwa "Sibutina" adọ aka ná ntị mmadụ na hainia diaphragm (esophageal aperture), nke a na-agbaso site reflux esophagitis.

Against ndabere nke a ọgwụ pụrụ ịmụba ọrịa adakarị ngosipụta nke arrhythmias, hyperthyroidism, prostatic hypertrophy, akwara akwara ọrịa na obi ọdịda, a-adịghị ala ala uwa.

Mụbara ihere okpomọkụ mgbe eji ọgwụ nwere ike ime fever na ọrịa nke obi (n'ihi na mbenata igba ajirija).

Ndị mmadụ na-na-arụ ize ndụ na-arụ ọrụ, na-achọ nlebara anya pụrụ iche na ọsọ mmeghachi omume, ọ dị mkpa iji dọọ aka ná ntị na isiokwu ọgwụ nwere ike ime ka bịara ikiri ọhụụ na iro ụra.

Nyocha na analogues

Analogues nke ọgwụ n'okpuru nyochaa ndị dị ka ndị: "Vesicare," "Detruzitol", "Dream Apo", "Spazmeks", "Driptan", "Zevesin", "Uroholum", "Urotol" na ndị ọzọ.

Nyocha banyere nke a agwọ ọrịa nwere ike izute a otutu. Ụfọdụ ọrịa afọ ju na irè nke ọgwụ. Ha na-ekwu na ọgwụ na-enyere akara urination, gụnyere n'abalị. Otú ọ dị, ọtụtụ ndị na-eme mkpesa banyere mmepe nke isi ọwụwa na allergies na ndị ọzọ siri Jeremaya mere. Na nke a, ha nwere iji dochie ọ pụtara nchebe analogues.