"Ebe nchekwa dị mma": ntụziaka maka iji, contraindications, mmetụta ndị ọzọ, nyochaa, foto

Kedu ihe ị maara banyere ọgwụ dị otú ahụ dịka Moditen Depot? A ga-atụle ntụziaka maka ojiji, contraindications, reviews na mmetụta ndị ọzọ nke ọgwụ a.

Nkwakọ ngwaahịa na ụdị nke nkwadebe, ya mejupụtara

Kedu ụdị ha si emepụta ọgwụ dịka Moditen Depot? Ntuziaka iji mee ka a mara na enwere ike ịzụta ya n'ụdị ngwọta mmanụ nke a chọrọ maka nchịkwa intramuscular. Isi ihe na-arụ ọrụ nke ọgwụ a bụ na-atụgharị na fluphenazine. Na ire ere, ọ na-abịa na ampoules nke iko gbara ọchịchịrị, na-akwadebe na ngwongwo cell na bundles akwụkwọ, n'otu n'otu.

Nkà ọgwụ

Kedu ụdị ọgwụgwọ nke "Ndozi Mgbanwe"? Ntuziaka iji mee ihe, nyocha na-arụ ụka na nke a bụ ọgwụ na-eme ogologo oge. Ọ bụ nke ndị na-ahụ maka neuroleptics na ihe ngosi ndị a na-akpọ antipsychotic Njirimara nke jikọtara ya na ụfọdụ arụ ọrụ na nsogbu antiemetic. Nakwa, ọgwụ a nwere mmetụta dị oke ogwu ogwu.

Kedu ihe kpatara arụmọrụ Mgbanwe Moditen? Ntuziaka iji mee ihe na-ekwu na arụ ọrụ antipsychotic ejikọtara ya na igbochi ndị natara dopamine D2 nke usoro mikododic na mesolimbic.

A na - egosipụta nkwupụta ọgwụgwọ nke ọgwụ a na - egosi n'ụzọ ziri ezi ma na - ahụ naanị mgbe ha na - eji ihe ngwọta dị elu. Ha na-akpata site na igbochi adrenoreceptors nke akụkụ dị iche iche nke ụbụrụ ụbụrụ.

Maka uru antiemetic nke ọgwụ a, a na-ejikọta ya na nchichi nke ndị na-anabata dopamine D2 na mpaghara mmebi nke etiti vomiting. Ekwesiri iburu n'uche na mmuta ogwu nke ọgwụ a na egosiputa n'onwe ya n'ihi igbochi ndi natara dopamine nke hypothalamus.

Ego ole ka ọgwụ "Mbibi dị mma" na-emetụta? Ntuziaka maka ojiji (ngwọta ọgwụ ntanetị n'isiokwu a) na-agwa gị na ọgwụgwọ ọgwụgwọ nke ọgwụ a na-egosipụtakarị onwe ya na awa 25-72 mgbe ojusịrị. Ekwesiri iburu n'uche na a na-ekwukarị na a na-akpọ ngwongwo ọgwụ ndị a jụrụ ajụjụ n'etiti 49 na awa 97 mgbe nchịkwa nke ngwọta.

Ogwu ogwu

Kedu ụdị ọgwụcokinetics bụ àgwà maka Ụlọ Nche Modit? Ntuziaka maka ojiji na-ekwu na fluphenazine n'ụdị ester dị arọ dị arọ, ihe ngwọta mmanu na acid fatty nwere ike ịkwakọba na ụlọ nkwakọba akụ, ma hapụkwa ya nwayọ.

Mgbe ogwusịrị ọgwụ na-emepụta ọgwụ, a ga-enweta ihe kachasị njọ nke mmewere a na plasma mgbe awa 25 gasịrị. N'okwu a, fluphenazine ejiri 90% jikọọ protein na ọbara.

Ọgwụ ọjọọ a na-atụle na-abanye na mgbochi nke placental ma na-abanye site na mgbochi ụbụrụ ọbara, na-adịghịkwa ewepụ ya n'ahụ site na hemodialysis.

Fluphenazine bụ kpamkpam ma na-etinye aka na imeju na imeju na ikere òkè nke enzymes nke usoro cytochrome P450. A na-ewepụ ya na ahụle na urine. Ihe omume nke metabolites nke mmewere a abughi ihe omumu.

Ọkara ndụ nke fluphenazine bụ 7-10 ụbọchị.

Ntu

N'ọnọdụ dị aṅaa ka onye ọrịa ahụ si kọwaa Moditen Depot injections? Ntuziaka maka ojiji na-egosi ihe ndị dị ka:

• Ihe omuma nke ihe omumu (maka mgbochi);
• Ogologo oge na-emezi usoro ọgwụgwọ nke ụdị ọrịa na-adịghị ala ala.

Ihe mgbochi iji

A machibidoro ọgwụ ahụ a jụrụ ajụjụ iji mee ihe n'okwu ndị a:

• Na ọrịa ndị SS siri ike, gụnyere mgbatị na-adịghị ala ala nke na-adịghị agwụ agwụ na nkwenye dị elu;
• Site n'icheta onye ọrịa ahụ na fluphenazine, tinyere ihe ndị ọzọ dị na ọgwụ ahụ;
• Site na mmegbu nke usoro nhụjuanya nke etiti;
• N'oge ime nwa;
• Site na ọnyá na okpokoro isi, yana ọrịa na-aga n'ihu na ụbụrụ na ụbụrụ;
• N'oge oge nri;
• Na-arịa ọrịa imeju na usoro ọbara;
• Ruo afọ iri na abụọ.

Jiri nlezianya jiri ọgwụ

N'iji nlezianya mee ihe, a na-eji ọgwụ "Depot Modeten" eme ihe maka:

• Alcoholism, nakwa dị ka ihe na-eme ka ndị mmadụ na-emegharị ahụ;
• Mgbanwe nke ọbara na-agbanwe na ọbara, nakwa dị ka imebi hematopoiesis;
• Mmetụta ndị na-emepụta ihe ndị na-akpata phenothiazine, gụnyere na anamnesis;
• Glaucoma na-emechi-n'akuku;
• Ọrịa ara;
• Hepatic na / ma ọ bụ ezughị ezu;
• Uwa nke tractestive tract, gụnyere n'oge oge nke ọrịa na-ebuwanye ibu;
• Hyperplasia nke prostate na ngosipụta ahụike;
• Miksedeme;
• Ọrịa ndị na - akpata nsogbu thromboembolic;
• Ọrịa Parkinson;
• Ọrịa ndị na-adịghị ala ala na-adabaghị iku ume (gụnyere ụmụaka);
• Reye's syndrome;
• Akwụkwụ, vomiting, ihe mgbochi;
• Cachexia;
• Na nká.

Ngwọta ọgwụgwọ "Ebe nchekwa dị mma": ntụziaka maka ojiji

N'elu ampoules, a na-eme ọgwụ a maka ọgwụgwọ ogologo oge (ọbụlagodi ọnwa atọ). Ya mbụ usoro onunu ogugu maka otutu ọrịa bụ 12.5-25 mg. Usoro nhazi nke oge a, nakwa nkeji n'etiti nchịkwa nke ngwọta, kpebisiri ike dabere na mmetụta ọgwụgwọ.

A ghaghị ịmalite nlezianya na-agwọ ndị ọrịa na-enwe mmetụta dị ukwuu na phenothiazine.

A chọrọ ndị agadi ka ha na-elekọta obere onunu karịa ndị na-eto eto (ihe dị ka 1/4 ruo 1/3 nke usoro ọgwụgwọ). N'otu oge ahụ, ha kwesịrị nyochaa mgbe niile.

Mmetụta dị na ya

Ihe ngwọta ọgwụ nke Moditen Depot nwere ike ịkpata mmeghachi omume na-adịghị mma:

• Ọrịa extratrampramidal, akathisia, dyskinesia na-egbu oge, dystopia, crises oculogic, hyperreflexia, opisthotonus;

• neuroleptic ajọ syndrome, nke nwere ike igbu;
• orthostatic hypotension, sweating, fluctuations na ọbara mgbali, ọgbụgbọ, hypotension, ọnwụ nke agụụ, glaucoma, oké salivation, atony eriri afo, polyuria, bowel mgbochi, akọrọ ọnụ, tachycardia, isi ọwụwa, bịara ikiri ọhụụ, afọ ntachi, ọ dịghị òkè mkpọchi;
• ventricular arrhythmias, ọnwụ mberede, ventricular tachycardia, gbasara obi njide;
• Ọrịa na-egbochi ọrịa, ọrịa ederede, mgbarụ nwa oge, hyponatremia, adịghị ike ụmụ nwoke, mgbanaka dị arọ, mgbanwe na libido n'ime ụmụ nwanyị;
• pruritus, exfoliative dermatitis, erythema, seborrhea, urticaria, anaphylactic Jeremaya mere, photosensitivity, angioedema, bronchial spasm, laryngeal edema;
• Agranulocytosis, leukopenia, jaundice cholestatic;
• Mgbagha ndị na-agbaghasị, ọkụ, mgbanwe ECG, nhụjuanya a na-apụghị ịgbagha agbagha, vomiting, thromboembolism venous, ọrịa lupus na ndị ọzọ.

Nyocha Nta

Ugbu a, ị maara ihe "nkwụsịtụ dị mma" na-esi n'aka. Ntuziaka maka ojiji, mmetụta ndị na-emetụta akụkụ ahụ na iji ihe ngwọta mee ihe maka ihe ngwọta a ka a tụlere n'elu.

Dị ka echiche nke ndị ọrịa bụ ndị na-ebute ụdị ọrịa antipsychotics dị iche iche, ọgwụ "Moditen Depot" na-arụ ọrụ n'ụzọ dị irè karị ma wepụ ihe ọjọọ niile nke mgbagwoju anya. Ntinye nke ọgwụ a na-ebute nkwụsị na ogologo oge.

Nanị ihe nkwụghachi nke ngwọta a bụ ọnụ ọgụgụ dị ukwuu nke mmeghachi omume. N'ụbọchị mbụ nke ọgwụgwọ, ụfọdụ ndị nwere ọrịa hyperthermia, ọbara mgbali elu na nsogbu autonomic. Ọzọkwa, ọtụtụ ndị ọrịa hụrụ hyperkinesis nke uru nke ọnụ na ihu, na-eme ka mmeghari nke ire na egbugbere ọnụ. Tụkwasị na nke a, iji ọgwụ a eme ihe na-emekarị ka ịda mbà n'obi dị njọ.