Glutamic acid: ndu ọrụ, ojiji na nkà mmụta ọgwụ na egwuregwu

Isi monoaminodikarbonovymi asịd bụ glutamic na aspartic asịd. Nke ikpeazụ mbụ dịpụrụ adịpụ ke 1868 site na osisi na-edozi. Nke a ihe onwunwe na-synthesized na ahụ mmadụ, bụ a bughi akụrụngwa nke ọtụtụ ndi na-edozi nke akwukwo nri na ụmụ anụmanụ si eji usoro nke biosynthesis nke nitrogenous bases nke nucleic asịd na urea na transamination nke amino asịd, wdg

Glutamic acid mbụ dịpụrụ adịpụ na 1966 site na a hydrolyzate nke gluten wheat ọka. A ịrịba ego nke ahụ kwuru kpọmkwem amino asịd na-dị na globulin na albumin. Glutamic acid bụ idem ke decarboxylation, transamination na deamination nke amino asịd. Na usoro nke Biochemical Jeremaya mere na umi kpụrụ tripeptide (glutathione) na onye ogbugbo ụjọ usoro (gamma-aminobutyric acid). Glutamic acid a na-na n'oge na-aghọ ihe na ọzọ na-ewu ewu. Ọ na-abịa n'ụdị nri nwekwara, ọgwụgwọ, mixtures ya a gụnyere ke mejupụtara maka egwuregwu oriri na-edozi.

The ndu ọrụ nke glutamate metụtara na mwekota nke nitrogen metabolism, njikọ nke ọzọ amino asịd, na biosynthesis nke carbohydrates, neutralization nke amonia. Ọzọkwa, a biosoedinenie na-ekerechi òkè ke kpụworo vitamin Sun, klas oxidoreductase enzymes, nucleotides na njikọ nke cyclic IGBOB (adenozinmonofosfatnaya acid), GMP (guanozinmonofosfatnaya acid) egosipụta ọgụgụ akwara mbufe ozi ọrụ. Glutamic acid bụ ike nke na-amụba myocyte permeability ka potassium ion. Ugbu a, e gosipụtara na glutamate nwere ike synthesized si arginine na histidine. Ikpeazụ ifịk ke metabolic Jeremaya mere (njikọ nke dipeptide anserine, carnosine). Carnosine - antioxidant, nke na-eme ka stabilization nke biomembrane muscle emep uta eri. Anserine egosi a mmetụta yiri. Ke adianade do, histidine activates moto ọrụ nke eriri afọ, mma ọtọ ọrụ nke imeju, enwekwu gastric secretion, nke nwere mmetụta bara uru na digestive ike nke alimentary kanaal.

N'oge na mgbakwunye na nke amonia na glutamic acid molekul kpụrụ glutamine. N'ihi ya, e detoxification nke amonia ke idem. Glutamic acid na egwuregwu na-eji dochie ike ọgwụgwụ. Large doses nke ọgwụ na-enwe ike ịnagide ike ọgwụgwụ nke uru ahụ n'ihi na ihe zuru ezu itinye n'ọrụ nke lactate na amonia detoxification. Glutamate egosipụta anabolic mmetụta megide eriri afọ ọwa, na skeletal muscle. Glucose na ụbụrụ glutamate eji dị energomateriala.

Ebe ọ bụ na sodium nnu nke glutamic acid nwere a flavor nke anụ, na biosoedinenie-eji dị ka a nri mmako. Ugbu a, ndị MSG na-agbakwunyere nri (soseji, sauces, bouillon cubes, ibe, crackers, wdg) ke fọrọ nke nta na mba niile nke ụwa.

Glutamic acid: ntụziaka

The kwuru pharmacological gị n'ụlọnga dị na mbadamba ụdị (25 mg). Na mbụ, iji ọgwụ e ndinọ n'okpuru oké intoxications, kwa ụbọchị dose adịghị gafere 10 grams. Dị ugbu a, na onunu ogwu ụba na 25 grams kwa ụbọchị. Na egwuregwu na nkà mmụta ọgwụ, ọbụna elu doses (30 100 g / ụbọchị). The agwọ ọrịa nke ala toxicity, ọ na-mgbe ụfọdụ hụrụ mmetụta n'ụdị nfụkasị Jeremaya, ogwe, ọgbụgbọ, vomiting, afọ ọsịsa na dizziness. Ukwuu ụwa klas na-eme egwuregwu na-edozi na-aṅụ ihe karịrị 120 g glutamic acid kwa ụbọchị. Otú ọ dị, ntuziaka na-egosi na kacha kwa ụbọchị dose ekwesịghị gafere 4 g

The ọgwụ na-kenyere ọgwụgwọ nke Akwụkwụ na-adọ, isi mgbaka, psychoses iche iche, na ịda mbà n'obi, ehighị ụra nke ọma, myopathies, nwata ọrịa ụbụrụ , wdg

Contraindications glutamic acid: ọrịa imeju, febrile cider, hypersensitivity, leukopenia, anaemia, nchegbu, gastric ọnyá afọ, nephrotic syndrome.