Ntuziaka maka ojiji - ampicillin

Na ezi a mgbe gara aga, ọ bịara mara na isi usoro nke ime mgbanwe dị iche iche iche iche nke bacteria na ọgwụ nje bụ β-lactamase na ha na ngwaahịa. Ha dị nnọọ irè so na mbibi nke na-echebe yiri mgbaaka ọgwụ nje na fọrọ nke nta ka ya ghara ịdị irè ha ọgwụgwọ mmetụta. Iji merie a mmetụta ọjọọ n'ahụ, ọ e mepụtara na ihe fọrọ kwadebere chemical ogige inactivate β-lactamase bụ n'ụzọ bụ isi clavulanic acid formulations sulbactam na tazobactam.

A ogige gụnyere dị ka ihe nke a na-akpọ penicillin ingibitorozaschischonnyh - jikọtara ọgwụ ọjọọ, nke na-agụnye penicillin ude. N'ịbụ ndị a maara ihe atụ nke ndị dị otú ahụ preparations bụ ampicillin-sulbactam, amoxicillin, ticarcillin na ndị ọzọ emejupụta ìgwè penicillins. Ha were bụ irè n'ihi na ha nwere ike ịrụ ọrụ dị ka akụkụ nke a dịgasị iche iche nke n'ịgwa nke ndị cephalosporin nke III ọgbọ, mgbe irè nke nọ n'ọrụ mgwa mụ na a elu larịị.

N'oge dị iche iche ihe n'ịgwa, na-eji ọtụtụ oge a na ọgwụ ọjọọ gụnyere a mejupụtara ọgwụ nje na inhibitors nke β-lactamase, e nwere a ọrụ bụ isi imu penicillins na ha na-fọrọ nke nta kpamkpam natara ha ọgwụgwọ nrụpụta na Iguzogide na ọtụtụ ndị mara staphylococci taa anaerobes na gram bacteria. Ke adianade do, ndị dị otú ahụ formulations na-ịgbasa ha antimicrobial ụdịdị dị iche iche. Ndị dị otú ahụ ọgwụ ọjọọ bụ nke ampicillin / sulbactam, nke dabere na emeputa ike ka a na-emepụta n'okpuru aha ma ọ bụ unazin Sulatsillin.

Nke a na ọgwụ na-agụnye ampicillin na sulbactam, nke nọ na a ruru nke 2: 1. Dị ka e gosiri site ntụziaka ntuziaka, ampicillin na sulbactam a nkwadebe ma e wezụga n'ezie igbochi β-lactamases nwere a pụtara akpọ ọrụ megide Neisserial na atsinetobakterov.

Na-emekarị n'ihi na esịtidem ọgwụ ẹkenọde kenyere sultamicillin, esịnede sulbactam na ampicillin. Mbadamba mgbe ẹkenọde etinye obi gị dum n'ime ahu. Mgbe ahụ mmeghachi omume nke hydrolysis na ikpokọta mmetụta gụnyere ọgwụ ampicillin na sulbactam, nke enhances bioavailability nke ampicillin ọbụna elu larịị nke na-imezu mgbe anata ihe hà dose nke omenala ampicillin.

Oputara a dịgasị iche iche nke ọrụ, na a ọgwụ. Ya mere, ojiji nke kasị ọgwụ ọjọọ na-egosi na-efe efe nke nje si TTP, Sinusitis dị iche iche shapes na etiology. The na nkà mmụta ọgwụ na-kenyere na ọrịa nke ala akụkụ okuku ume na tract: ala ala bronchitis, ka oyi baa.

Dị ka ntuziaka maka ojiji, ampicillin na sulbactam ọdịnaya bụ irè na ọgwụgwọ nke dị iche iche nke intraabdominal na pelvic na-efe efe, gụnyere adụ anụ ahụ na-efe efe, ọkpụkpụ na nkwonkwo na-efe efe, septicemia.

The nkwadebe nke ampicillin na sulbactam budata ọzọ irè tụnyere amoxicillin / clavulanate na ọgwụgwọ nke na-efe efe nke na-butere atsinetobakterom.

The onunu ogwu nke ọgwụ na-ekpebi ntuziaka maka ojiji. Ampicillin na-kenyere ọnụ, ndị dose n'ihi na ndị okenye bụ na 0,375-0,75 grams n'agbanyeghị nke nri ugboro abụọ n'ụbọchị, ma ọ bụrụ na ọrịa ahụ dị mfe agwa. Na ọzọ oké forms nke ọgwụ na-eji 1.5-3.0 grams nile ụbọchị mgbe ogo na-amụba, na onunu ogwu nwere ike mụbara ka 6.0 grams.

Ụmụ ọhụrụ ọgwụ ndinọ na doses gbakọọ banyere 50 micrograms kwa ụbọchị kwa otu kilogram nke arọ nke nwa. Admission a rụrụ ugboro abụọ.

Hapụ ụdị na onunu ogwu nke ọgwụ na-akọwa n'ụzọ zuru ezu na ntuziaka maka ojiji. Ampicillin nwekwara ike iwere ma e wezụga mbadamba nkume n'ụdị powder iji kwadebe pụrụ iche nkwusioru (mgbe ọnụ ndinọ). Na nyere ojiji nke ọgwụ site ogwu ogbugba, n'ihi na nke a na ọ na-emepụta na ntụ ntụ ụdị. The mgbaze ọnọ na ọgwụ na otu ngwugwu.