Ọgwụ: ndepụta na-agba akaebe. Ukwuu ifịk alụso nje virus ọgụ ọgwụ

HIV bụghị a mkpebi taa. Ọrịa nwere ike n'enweghị na-ebi ndụ a ọrịa, na-arụ ọrụ, na-amalite a na ezinụlọ. All mkpa ka ị na-eme - bụ na-ata mgbe ọgwụ na alụso nje virus ọgụ chemotherapeutic mmadụ. A niile ụlọ ọrụ na-ekewa atọ ọmụmụ: na HIV protease inhibitors, abụọ n'ime ndị na-abụghị abụọ n'ime HIV reverse transcriptase inhibitors.

Ọ bụ uru na-echeta na ọgwụ ike-kpamkpam gwọrọ nke AIDS. Amụma mkpuchi megide ọrịa a na-adịghị aga nke ọma. Drugs naanị inhibit ndị multiplication nke nje, aka mma ọrịa na-arịa. N'okpuru ebe a ga-akọwara ndị kasị rịọrọ antiretrovirals.

"Lamivudine"

Ukwu na-ezo aka a ìgwè nke abụọ n'ime HIV reverse transcriptase inhibitors. Antiviral gị n'ụlọnga penetrates n'ime mkpụrụ ndụ na metabolized e, si otú eme mgbochi nke malitere ịrịa replication. Method nke ọgwụgwọ nke HIV-ọrịa na-eji a ọgwụ ọjọọ, "Lamivudine" na-egosi elu arụmọrụ. The ngwá ọrụ na-arụsi ọrụ ike megide ịba ọcha n'anya B. The ọgwụ na-ngwa ngwa etinye obi gị dum ezu si eriri afọ tract. Otu awa mgbe ingestion bioavailability ọbara plasma esịmde egosi 80%. Communication plasma protein bụ 30%. Ọ ga-iburu n'uche na-arụsi ọrụ ike akụrụngwa bụ mfe obe na placental mgbochi.

Drug "Lamivudine" a na-eji maka ọgwụgwọ nke HIV na ndị okenye na ụmụaka. Ọtụtụ mgbe ọgwụ na-eji dị ka akụkụ nke Nchikota ọgwụ (nhọrọ ojiji nke ọzọ antiviral mmadụ maka ọgwụgwọ nke HIV). Ọzọkwa ọgwụ ike ga-ndinọ na-adịghị ala ala malitere ịrịa ịba ọcha n'anya B. The ọgwụ na-adịghị contraindicated n'oge ime na lactation. The owuwu nwere ike ji mee ihe maka ọgwụgwọ nke ụmụ ọhụrụ. Kwụsị iji ọgwụ ọjọọ na-akwụ ụgwọ naanị na ihe omume na e nwere ihe ubara uche na mmiri.

ọgwụ interactions

Joint n'ikuku pụtara "Lamivudine" na "Zimavudin" omume. Ọ bụ uru na-ewere na ndị bioavailability nke ọgwụ ọjọọ budata belata. Ọ na-adịghị atụ aro iji ma ọgwụ, nke na ya na mejupụtara nwere didanosine ma ọ bụ sulfanilamin. Ileghara ime otú ahụ nwere ike na-eduga nkpasu-iwe nke pancreatitis. Budata enwekwu ịta nke nọ n'ọrụ bekee - lamivudine - ọbara ọgwụ "TMP".

Agwọ na-mụụrụ naanị na ndenye ọgwụ. Zụrụ na ahịa ọgwụ nwere ike ịbụ a na-agwọ ya "Lamivudine" na-enweghị a ọgwụ. The price nke ọgwụ bụ 3,500 rubles. The onunu ogwu na ọgwụgwọ Usoro ọkachamara tent, dabeere na onye e ji mara onye ọrịa, na ụdị ọrịa ahụ.

The ọgwụ ga-eji anya akpachapuru anya nke na mkpọchị gbasara akụrụ ọrụ. The agwọ ọrịa nwere ike kenyere otu ọkà kacha nta onunu ogwu ọnụego ma ọ bụrụ na QA bụ ihe na-erughị 50 ml / min. Emebe ọgwụgwọ Usoro, ndị dibịa ga-gaa na akaụntụ na-arụsi ọrụ ike akụrụngwa na-egosi tumadi na akụrụ ya. Ndị na-mkpọchị imeju ọrụ onunu ogwu ukpụhọde a chọrọ. Mgbe ị na-ahụ ndị dị otú ahụ egwu mgbaàmà dị ka abdominal mgbu, ọgbụgbọ, vomiting, pụtara "Lamivudine" ga-kagbuo. The ọkachamara enịmde nyochaa onye ọrịa. Agwọ nwere ike maliteghachiri naanị mgbe nchoputa na-achị "nnukwu pancreatitis".

Irè na ọgwụgwọ nke ọrịa AIDS bụ "Lamivudine". Price nke ọgwụ bụ dịtụ ala. Ọ bụ uru na-echeta na ọ dịghị ọgwụ ike echebe megide ọrịa site n'ọbara ma ọ bụ inwe mmekọahụ. The ọgwụ ike ga-eji dị ka a prophylactic.

"DdI"

The antiviral ọgwụ bụ ukwuu n'ọrụ megide HIV. Ndị ọkachamara na-ugboro ugboro ji pụtara "Didanosine." Guide na-akọwa usoro nke ngwa, ndị na-egosi na usoro onunu ogwu. The ọgwụ dị na ụdị mbadamba, chewable mbadamba, capsules. Na enyemaka ha, na-ekwe omume iji kwadebe a slurry. Active akụrụngwa bụ didanosine. Ọzọkwa, dị bekee na-eji, dị ka aspartame, magnesium hydroxide, titanium dioxide, sorbitol, calcium carbonate, magnesium stearate, na tanjerịn flavor. N'aka na-emepụta na a onunu ogwu nke 100, 125, 200 na 400 mg.

Didanosine bụ a sịntetik abụọ n'ime analogue dioksiadenozina suppresses HIV omume na mkpụrụ ndụ nke ahụ. The bioavailability nke nọ n'ọrụ mgwa esịmde 60% otu hour mgbe na-ewere ọgwụ ọjọọ na ime. More irè ọgwụ uche, ma ọ bụrụ na ọ na-eji otu awa tupu eri ma ọ bụ 2 awa mgbe a nri. Jiri ọnụ na nri-ebelata bioavailability nke nọ n'ọrụ mgwa na 50%. Egosipụta ọgwụ site imeju na-na akụrụ. Metabolism didanosine adabere ruo n'ókè nke gbasara akụrụ ọrụ.

The agwọ ọrịa nwere ike-eji naanị na Nchikota na ndị ọzọ antiviral ọgwụ ọjọọ na-emeso nje HIV. The agwọ ọrịa na-ekwe ka inye ndị inyom n'oge gestation na lactation. Ọ bụghị contraindicated pụtara "ddI" na ụmụaka. Inye a ọgwụ naanị ụmụ ọhụrụ ruo afọ atọ. Kagbuo ọgwụ dị mkpa na ihe omume na e nwere ihe na ụba uche na isi na akụrụngwa. Ndị na-isi imeju ọrụ agwọ ọrịa ga-eji na-ekwesịghị.

Olee na-na nkà mmụta ọgwụ?

Physician akọwaputa onunu ogwu dabere na ogo nke ọrịa, na onye e ji mara nke onye ọrịa. Alụso nje virus ọgụ ọgwụ nwere ike rụrụ dị ka na-atụ aro kpọmkwem na ntụziaka. Ọnụego ya kwa ụbọchị na-adabere na ahu aro. Ndị arọ adịghị gafere 60 n'arọ, ga-ọ dịghị ihe karịrị 250 mg nke ọgwụ kwa ụbọchị. Maka ọrịa erikpu karịa 60 n'arọ, na onunu ogwu nwere ike iru 400 mg. Capsule ẹka otu ugboro n'ụbọchị. Ha apụghị ata. Ọ kwesịrị iwere na ọtụtụ mmiri. Ọ na-atụ aro na ọgwụ ke usenubọk, na ihe efu afo.

Mbadamba nwekwara ike iji kwadebe a slurry. All mkpa ka ị na-eme bụ itughari na gị n'ụlọnga a obere ego nke sie mmiri. All kwa ụbọchị ọnụego nwere ike kewara abụọ nzọụkwụ. Akwadebe a nkwusioru ike ịchekwa n'ihi na ihe karịrị otu awa. Na mgbede, n'aka kwesịrị iwere tupu na-aga bed na 2 awa mgbe a nri. Children n'okpuru 5 afọ nke nkà mmụta ọgwụ na-họpụtara naanị n'ụdị a nkwusioru.

Ọrịa mgbe afọ 70 rụrụ a dose ukpụhọde. Nke a bụ n'ihi na eziokwu na na agadi nsogbu n'obi gbasara akụrụ ọrụ. Standard kwa ụbọchị ọnụego nwere ike ime ka mmetụta dị otú ahụ dị ka pancreatitis, elu neuropathy, lactic acidosis. Na akụkụ nke eriri afọ tract nwere ike ịzụlite wetara phenomena dị ka akọrọ ọnụ, anorexia, ọgbụgbọ, vomiting. Ọ bụrụ na arịa ọrịa nke na ahụ ike onye ọrịa na-atụ aro na-etinye maka a oge na a ọkachamara. Ma eleghị anya, ọgwụ ga-kagbuo. Doctor ga nye iwu a quality dochie ( "Thymidine" ma ọ bụ analogs nke "Thymidine", "ABC", "Lamivudine").

"Videx"

Active akụrụngwa nke a ọgwụ bụ nwekwara didanosine. Ọgwụ si otu a na n'ọtụtụ ebe, na-eji na ọgwụgwọ nke nje HIV. The mma bụ eziokwu bụ na ọgwụ ike ga-eji maka ụmụ ọhụrụ na-amụ ije. Nta ọrịa gị n'ụlọnga "Videx" na-kenyere n'ụdị a powder maka nkwusioru. Ọnụọgụ ọgwụ na gbakọọ n'otu n'otu dị na ogo nke ọrịa, na onye e ji mara nke onye ọrịa. Unu na-eji ọgwụ ọjọọ ma ọ bụrụ na-emepe emepe hypersensitivity ka didanosine.

Alụso nje virus ọgụ ọgwụ a rụrụ ozugbo nchọpụta nke ndị ọrịa. Dị ka a mgbochi ọgwụ adịghị mee ihe. Ọgwụ nwere ọ nweghị contraindications. Mbadamba ma ọ bụ ntụ ntụ "Videx" adịghị eme ka mmetụta, ma ọ bụrụ na kwesịrị ekwesị họrọ onunu ogwu Usoro. Kagbuo ọgwụ kwesịrị ọ bụrụ na e a enyo maka mmepe nke pancreatitis.

"Ṅụrụ ọgwụ"

The antiviral ọgwụ bụ ukwuu n'ọrụ megide HIV. Active akụrụngwa bụ zidovudine. Ntuziaka maka ojiji na-akọwa na auxiliaries. Ndị a gụnyere pregelatinized starch, magnesium stearate, microcrystalline cellulose. The film mkpuchi na-ugbua ka enwere titanium dioxide, polydextrose, glyceryl kaprilokaprata. A ọgwụ na-eji dị ka akụkụ nke Nchikota ọgwụ, dị ka HIV-1 ọrịa. N'oge ime, ọgwụ ike ga-eji dị ka mgbochi nke perinatal nnyefe nke virus si nne nwa ebu n'afọ.

The na nkà mmụta ọgwụ nwere ọtụtụ contraindications. Mbadamba "ṅụrụ ọgwụ" na-adịghị ndinọ ka ụmụ na okenye ọrịa erikpu erughị 30 n'arọ. Na obere okwu, o nwere ike ịzụlite hypersensitivity na-arụsi ọrụ ike akụrụngwa. Nabatara ọgwụ ọjọọ ahụ, n'agbanyeghị na nri. Ndị zụrụ ngwaahịa "Zidovudine 300", ị ga-eji mbadamba nkume abụọ kwa ụbọchị. Ọ bụrụ na onye ọrịa ji karịa 60 n'arọ, ọ dị mkpa na-20 mg nke ọgwụ ugboro abụọ n'ụbọchị.

Ọ na-ezo aka a otu nke elu-ọnụ ọgwụ ọjọọ, "ṅụrụ ọgwụ". The price nke otu mkpọ 60 mbadamba ihe karịrị 10 000 rubles.

"Abacavir"

N'ọrụ akụrụngwa nke mbadamba bụ abacavir sulfate. The ọgwụ na ọtụtụ-eji antiviral ọgwụ nke HIV. Ọzọkwa, mbadamba na-agụnye ndị na-esonụ components: microcrystalline cellulose, ígwè oxide odo, Polysorbate, titanium dioxide, magnesium stearate, Opadry Yellow, triacetin. Ọgwụ nwere ike na-eji dị ka akụkụ nke Nchikota ọgwụ. Ọ bụghị kenyere mkpụrụ ọgwụ "ABC" bụrụ na nke hypersensitivity na isi akụrụngwa. Ọgwụ contraindicated na-eto eto na-arịa ọrịa onye ibu adịghị gafere 14 n'arọ. Anya kwesịrị ọgwụ nke ọrịa na gbasara akụrụ insufficiency.

The onunu ogwu nke ọgwụ na gbakọọ n'otu n'otu dị na udi nke onye ọrịa ahụ ọrịa. N'ihi na ndị okenye, nkezi kwa ụbọchị oriri bụ 600 mg kwa ụbọchị (kere atọ òkè). Iji mbadamba ihe mụbara onunu ogwu nwere ike na-eduga mmepe nke nfụkasị Jeremaya.

Ọzọkwa kwuru na dị ka a oké ọnụ n'aka "ABC". The price nke otu mkpọ mkpụrụ ọgwụ nwere ike gafere 15 000 rubles.

"Ziagen"

Active akụrụngwa, dị ka na aga na ikpe, bụ abacavir sulfate. Preparations bụ analogues na ya nwere ike dochie ọ bụla ọzọ. Pụtara "Ziagen" n'ụzọ dị irè na-eji na ọgwụgwọ nke nje HIV. The na nkà mmụta ọgwụ na-enyere aka melite ọrịa na-arịa, laghachi kwesịrị ndụ. The mbadamba nwere ọ nweghị contraindications. Ọ na-adịghị kenyere ọgwụ naanị na ọrịa onye ibu adịghị gafere 14 n'arọ.

Ọnụego ya kwa ụbọchị nke ọgwụ kpebisiri ike site dọkịta. Ọ na-ewe echiche ụdị ọrịa, nakwa dị ka onye e ji mara ọrịa (arọ, afọ). Ụmụ ọhụrụ ndị itu erughị 20 n'arọ, ndinọ na ọkara mbadamba ugboro abụọ n'ụbọchị. Daily ọnụego onye okenye ndidi pụrụ iru atọ mbadamba kwa ụbọchị.

Ezughị oke ojiji nke ọgwụ ike na-eduga mmepe nke mmetụta. Ọ ga-achọ enyemaka si a dọkịta ma ọ bụrụ na ị na-azụlite mgbaàmà ndị dị otú ahụ dị ka afọ ọsịsa, abdominal mgbu, ọgbụgbọ na vomiting. Ihe omume ndị a nwere ike na-egosi pancreatitis. Ọzọkwa ugboro ugboro hụrụ nfụkasị Jeremaya n'ụdị ọkụ ọkụ na itching.

"Ziagen" mkpụrụ ọgwụ nwere ike nke ọma ga-anọchi a n'aka "ṅụrụ ọgwụ". The price nke ọgwụ ọjọọ bụ ihe fọrọ nke nta ka yiri.

"Olitid"

The antiviral ọgwụ nọ n'ọrụ megide HIV. Active akụrụngwa - abacavir sulfate. The ọgwụ dị na ụdị powder maka nkwusioru, na mbadamba. Pụtara "Olitid" nwere ike na-abụ akụkụ nke mgbagwoju ọgwụ. Self-ọgwụ na-adịghị na-eji. The onunu ogwu nke ọgwụ kpebisiri ike site dibịa. The mbadamba ụdị nkwadebe ike ga-eji naanị maka ọrịa onye ibu karịa 14 n'arọ. -Nọgide họpụtara "Olitid" mkpụrụ ọgwụ na agadi. Nke a bụ n'ihi na ihe ize ndụ nke gbasara akụrụ dysfunction.

Ọgwụ, gụnyere ọgwụ "Olitid" na-eji nditịm maka nzube ọkachamara. Ịzụta ọgwụ na a na-ere ọgwụ na-enweghị a ọgwụ nwere ike ịbụ.

"Retrovir"

A ọgwụ ọtụtụ-eji mgbagwoju ọgwụ nke HIV. Mgbe ingestion gị n'ụlọnga ngwa ngwa etinye obi gị dum na eriri afọ tract. Active akụrụngwa mfe penetrates na placental mgbochi. Nke a na-sonye na akaụntụ mgbe na-emepe emepe ọgwụgwọ regimens ka nwanyị dị ime. The agwọ ọrịa nwere ike ji mee ka a ọkachamara HIV mgbochi. Nke a dị mkpa karịsịa maka laabu ndị ọrụ na-eduzi nnyocha nke mmeru ihe.

Ọnụọgụ ọgwụ kpebisiri ike n'otu n'otu site na ịga dibịa. Oke kwa ụbọchị ọnụego n'ihi na ndị okenye nwere ike gafere 600 mg. Ọkachamara nwere ike ikwu na kee ya atọ òkè. A ọzọ irè n'aka ga-abụ ma ọ bụrụ na ị na-na ọ na ihe efu afo. Na omume nke ọ bụla mmetụta kwesịrị ịkpọ na a dibịa.