Buserelin ebusa - nkọwa na ngwa atụmatụ

Oke nke a mmiri ọgwụ ọgwụ ga-dabere na a nlezianya na-amụ ihe mgbaàmà na a akpachara anya njirimara nke ihe ize ndụ nke mmetụta.

Nkwadebe "Buserelin ebusa" tụnyere mma na ndị ọzọ nke elu arụmọrụ na ala puru nke oghom mgbaàmà. Ọ bụ onye so na mmiri ọgwụ anticancer mmadụ.

The pharmacological edinam nke ọgwụ

The edinam mejupụtara buserelin antigonadotropnym, mgbochi androgenic, mgbochi estrogen, mgbochi akpụ mmetụta. Drug umi "Buserelin ebusa" by mpi jikọtara na-anabata ya nke mkpụrụ ndụ secreting gonadotropin-atọhapụ ihe na-akpata (ha nọ Ọdịdị nke ahụ ihu n'ọnụ ọnụ nke pituitary gland).

Ke akpa ogbo ọgwụ input a hụrụ a-akwụsị akwụsị na-abawanye na ịta nke LH na FSH (gonadotropic hormone), ekenyela site pituitary, nke na-eduga ụba Genital Gomonov ọdịnaya. Mgbe 14 - 21 ụbọchị igbochi pụtara gonadotropic ọrụ site na-ezighị ezi feedbacks, nke na-eduga ná a dị ịrịba ama Mbelata LH na FSH, na, dị ka a N'ihi ya, na a ọnụ na mmepụta nke mmekọahụ homonụ. N'ihi ya, nwoke testosterone ịta mbelata, ọ esịmde a larịị nke na-guzosie ike mgbe orchiectomy (ọgwụ castration). Women ọgwụ mmetụta "Buserelin ebusa" na-lowered ka larịị nke mmepụta estradioda ẹdude na posklimaktericheskom oge.

Iji ọgwụ ọjọọ, "Buserelin ebusa"

Ọ na-eji na ọgwụgwọ nke prostate cancer, na ụfọdụ, na-ebelata testosterone mmepụta ke testes. Ọzọkwa-eji na ọgwụgwọ nke ọrịa ara ure (hormone-ndabere ọrịa, nke e ji elu mmepụta nke estrogens ma ọ bụ na-egosi na endometriosis). Ọrịa ndị ọzọ, na-emeso "buserelina ebusa": eriri akpa nwa fibroids, endometrial hyperplasia, na-eduzi ndị IVF omume n'ịgwọ infertility.

Contraindications na pụrụ iche na-atụ aro

Hypersensitivity, orchiectomy, afọ ime, lactation. Anya na-ewere ọgwụ na daa ọrịa nke urinary tract n'ogo nke vertebral metastasis, ọbara mgbali elu, ọrịa shuga, na ịda mbà n'obi. Buserelin ebusa na ime - emegide echiche.

mmetụta

Onye ọrịa pụrụ ime mkpesa nke malaise na akụkụ nke Central ụjọ usoro n'ụdị isi ọwụwa, ịma jijiji, ehighị ụra nke ọma, obi nchefu, ebelata ịta, dizziness, obi akwusighi, na mgbe ụfọdụ ịda mbà n'obi. Ọ nwere ike obi tinnitus ma ọ bụ nsogbu na na nwa anya, bịara ikiri ọhụụ ma ọ na-anụ. Ọ pụrụ mgbe mgbe "na-ekpo ọkụ mgbukepụ." Ke akpa izu nke ọgwụgwọ na inyom hụrụ psevdomenstruatsiya, mgbe ahụ, ka ndị mmamiri nkụ, o kwere omume ọkpụkpụ demineralization, ebelata libido. Na ndị mmadụ, ọrịa nwere ike enwe nnukwu ke akpa 2 - 3 izu, ma ọ bụ na-egosi gynecomastia, belata potency. Kpọmkwem otu nwere ike ime: anorexia, dyspeptic ọrịa. Buserelin ebusa na mmanya chere. Na ọrịa na ọbara mgbali nwere ike nsogbu, obi ọnụego. Site nfụkasị Jeremaya ime: itching, ọkụ ọkụ, bronchospasm, anaphylactic ujo. Na-agbanwe agbanwe laabu egosi: dyslipidemia, hyperglycemia, na-abawanye na transaminases na bilirubin, thrombocytopenia na leukopenia.

The ụkpụrụ nke ọgwụ

Intramuscular ochichi: ndinọ ozugbo njikere nke nkwusioru.

- mgbe prostate akpụ 4 ọ bụla izu 4.2 mg.

- Endometriosis - na ẹkenam n'ime 4 ọnwa.

- na eriri akpa nwa myoma -3 ọnwa.

- infertility - 4.2 mg.

Intranasal ochichi:

- maka ọgwụgwọ nke nne na ọrịa ahụ a kọwara n'elu - ndinọ ka gọzie gị oghere 900 mg / ụbọchị (otu dose, 3 ugboro n'ụbọchị), site 1 - 2 ụbọchị nke ịhụ nsọ okirikiri.

- infertility 600 mg / ụbọchị, 1 dose na gọzie gị oghere ugboro anọ kwa ụbọchị. Ọ bụrụ na ike na-egosipụta mgbochi nke omumu usoro, ndị dose na-ebelata ka 2 ugboro.

Ụfọdụ kwuru, sị:

- Ọgwụgwọ nke prostate cancer na-rụrụ ná ndụ;

- mgbochi androgen ọgwụ ọjọọ ndinọ maka izu 2. na maka izu 2. nke ọgwụgwọ na buserelin, na-egbochi nsogbu ahụ nwere ike ime n'oge akpa izu nke ọgwụgwọ;

- ke akpa oge nke ọgwụgwọ na ndị inyom nwere ike iyi ovarian ahu otutu;

- kwesịrị gbochie afọ ime na ogwu-anata ọgwụ na-emeso buserelin, ma mbụ 2 ọnwa bụ mkpa na-eji ndị na-abụghị mmiri ọgwụ ụzọ nke mgbochi;

- a mma utịp ke ọgwụ ọgwụgwọ nke endometriosis surgically site na mbenata ugboro nke nlọghachi.

Mmekọrịta ndị ọzọ ọgwụ ọjọọ eme ihe

Buserelin ebelata mmetụta nke hypoglycemic ọgwụ ọjọọ. Ọ nwere ike ime ka ovarian hyperstimulation, ma ọ bụrụ na-eji ọnụ na ọgwụ ọjọọ gụnyere mmekọahụ homonụ.