Drug "Divigel" maka uto nke endometrium: reviews nke dọkịta na ndị ọrịa, ndị dose

nwanyi infertility nsogbu n'oge bụ nnọọ nnukwu. Ihe mere nwere ike dị iche iche - si a dịgasị iche iche nke mkpali oria nke Genital akụkụ, na nsogbu na endocrine usoro. Otu n'ime ihe ndị kasị ihe - ọ bụ ihe ezughi oke ọnụ ọgụgụ nke nwanyi estrogen. Ha isi ọrụ - iji kwadebe ihe n'ime oyi akwa nke akpanwa ka o doo nke egg.

Iji kpochapụ a mwepu, nwanyi dọkịta idepụta ọgwụ nwere kwuru hormone. Otu n'ime ndị a ọgwụ ọjọọ eme ihe bụ "Divigel" maka uto nke endometrium, ọrịa nti reviews banyere ya, na ọtụtụ ndị inyom na-atụrụ ime n'enweghị nsogbu.

ọgwụ

"Divigel" arụpụtara site emepụta n'ụdị a transdermal jel na-eje ozi iji kpochapụ ihe ịrịba ama nke enweghị estrogen. Ọ bụ a edo mejupụtara na packaged na aluminum akpa.

Na ya mejupụtara nwere a jel:

• Estradiol ke ichekwa 500 mg ma ọ bụ 1 g
• Carbomer 974P.
• Triethanolamine.
• Propylene glycol.
• 96% ethyl mmanya.
• Ọcha mmiri.

The pharmacological edinam nke ọgwụ

"Divigel" na-ezo aka a ìgwè nke ọgwụ ọjọọ nke na-eji maka mgbazi nke ọrịa mere site menopause na a nwaanyị ndụ. Ọ nwere estrogenic ọrụ.

The ọgwụgwọ mmetụta a na-enweta mgbe ngwa ọrụ nke estradiol. Nke a estrogenic gị n'ụlọnga na e dere "Divigel" maka uto nke endometrium, na ya ndu, chemical na pharmacological Njirimara yiri endogenous estradiol, synthesized site ovaries na nwanyi ahu.

Ọ bụrụ na ị na-nhazi ọkwa nke ọgwụ ọjọọ, estradiol-agụnye ọtụtụ pharmacological iche iche:

1. Estrogens, progestins, ha homologues na-akụ ọkpọ.
2. Antineoplastic mmiri ọgwụ na hormone-akụ ọkpọ.

N'ọrụ ọgwụ umi jupụtara n'ime enweghị nwanyi homonụ estrogen ihe nnabata na-akpali ọrụ dị na iche na mkpụrụ ndụ.

Pharmacokinetics

Estradiol ẹdude ke jel site mgbasa penetrates kpamkpam n'ime lekwasịrị mkpụrụ ndụ, ebe gaa na ntọala ma Nleta a nkekọ na estrogen anabata. Ndị a na-anabata ya na-hụrụ dị iche iche anụ ahụ. Ma, ọtụtụ n'ime ha na-hụrụ n'ime akpanwa, imeju, ovaries, ọkpụkpụ na ara.

N'ọrụ akụrụngwa nke jel - 17-beta-estradiol - nwere ndị na-esonụ na-akpata:

• Ọ-akpali mmepe nke nwanyi omumu usoro.
• Ọ na-akpata pigmentation na ọnụ ara.
• Ọ na-enye jụrụ endometrium nke edoghi akpanwa.

• Ọ na-enye a mgbe ịhụ nsọ okirikiri.
• Ọ na-akwụsị mmepụta nke mmiri ara.
• Ọ nwere procoagulant mmetụta.
• Ghaghị emetụta mweghachi nke ọnụ ọgụgụ nke mkpụrụ ndụ ọbara ọcha mgbe radieshon mebiri.

Na estradiol ka nwere ọtụtụ ihe dị mkpa àgwà, nke na-agụnye:

• Prevention of atherosclerosis.
• Mmụba na ọbara etoju nke HDL.
• Mbenata LDL egosi.
• Mbenata ego nke cholesterol.

Mgbe menopause na a nwaanyị ovaries kwụsị amị estradiol, ọrụ a na-anọgide na imeju na-na adipose anụ ahụ. Belata estrogen etoju na-eduga ná eziokwu na e vasomotor akwusighi gosi na flushing, ụra nsogbu.

Ọzọ na-adịghị mma n'ihi na enweghị estrogen bụ mmepe nke osteoporosis. Nke a metabolic ọrịa were isi ọkpụkpụ azụ.

Mgbe anata estradiol ọnụ n'ụdị mbadamba, injections bụ a jiri nwayọọ nwayọọ na ìgwè nke umi ke idem, nke na-eduga a ịrịba ọbara mgbali na-awụlikwa elu. "Divigel" maka uto nke endometrium reviews na nke a dị mma, onye ọrịa mgbe na-enweghị mara ọbara mgbali.

The jel e mere na ndabere nke na-aba n'anya, ma mgbe na kọntaktị na akpụkpọ, ethanol anwụ na-amịrị ngwa ngwa, na-arụsi ọrụ ike umi penetrates ákwà na etinye obi gị dum n'ime n'ọbara. A obere ego nke estradiol na-egbu oge na akpụkpọ, na mgbe ahụ ji nwayọọ nwayọọ tọhapụrụ n'ime n'ọbara.

N'oge ọgwụgwọ "Divigel" ruru n'etiti estrone na estradiol bụ site 0.4 na 0,7. The bioavailability nke ọgwụ - 82%. Ọgwụgwọ nrụpụta ga-adabere na na otú e si eji "Divigel" maka endometrial ibu.

na-agba akaebe

The jel, ndị dọkịta nwere ike ikwu na-ewere dị ka a hormone nnọchi ọgwụ ndị inyom bụ ndị nwere a enweghị estrogen ruru ka ndị dịgasị iche. The ọgwụ na-kenyere iji kpochapụ climacteric syndrome.

The jel pụtara onwe ya dị ka a mgbochi ụfọdụ, gbochie osteoporosis. Positive nzaghachi bụ "Divigel" maka endometrial ibu na IVF ka a nkwadebe na-ekwusi a nkịtị ime.

The ọgwụ na-ndinọ na onye onunu ogwu nke na-họrọ ịga dibịa n'ụlọ ọgwụ ahụ usoro e rụrụ njikọta. Na-amalite iji ya mma na a di na nwunye nke izu tupu a tụrụ ime na-anọgide ebede maka ihe a ọnwa.

Mgbe ime nchupu ngwa agaghị inikiet inikiet, dị ka na nke a, e nwere ihe ize ndụ nke n'amaghi-ete ime.

Ọ bụrụ na e kenyere "Divigel" maka endometrial ibu, na onunu ogwu họrọ na nke ọ bụla iche iche. N'oge ime atụmatụ dọkịta ga-hụ na i nwere hypoplastic endometrium na -akpali ovulation na-mkpa ime ka eji jel jikọtara ndị ọzọ mmiri ọgwụ na ọgwụ ọjọọ. Na nke ọ bụla, na ọgwụgwọ Usoro ga ịdị iche iche.

contraindications

Tupu figuring otú e si lee "Divigel" maka uto nke endometrium, ị ghaghị ijide n'aka na ọ dịghị contraindications na nke a, ha nwere a zuru ezu ego nke ọgwụ. N'etiti ha, ihe ka ọtụtụ ndị na-esonụ:

1. Hypersensitivity na mmiri.
2. Ọnụnọ nke ọrịa ara ure, ma ọ bụ ọ bụrụ na ọ nọwo na ihe mere eme.
3. Ịza aza etuto ahụ na ovaries, akpanwa.
4. Ọnụnọ nke benign etuto ahụ na Genital akụkụ ke obi.
5. Pụrụ ịrịa eriri akpa nwa ọbara ọgbụgba.
6. Endometrial hyperplasia.
7. Pituitary etuto ahụ.
8. Mkpali oria nke Genital akụkụ.
9. Mụbara estrogen ọdịnaya.
10. Thrombophlebitis.
11. Ọnụnọ nke etuto ahụ na imeju.
12. Mgbaàmà nke ọrịa ụbụrụ mgbasa.
13. Sickle cell anaemia.
14. Mebiri nke abụba metabolism.
15. Diabetes mellitus.
16. Ọrịa nke etiti ntị.

Akpan akpan ịkpachara anya mgbe eji jel ga-hụrụ ka ụmụ nwanyị kwuru, sị:

• Bronchial ụkwara ume ọkụ.
• Migraine ọgụ.
• Ọbara mgbali elu.
• Gbasara obi, gbasara akụrụ ma ọ bụ hepatic ọdịda.
• Ọrịa obi na ọrịa.
• Ọchịchọ edema.
• Fibrocystic ara ọrịa.

Inwe ndị a niile contraindications na ịdọ aka ná ntị na-egosi na tupu ajụ ajụjụ nke otú iteto "Divigel" maka uto nke endometrium, ọ bụ amanyere bụ iwu gaa a ọkachamara, na ya na ya na-ekwurịta okwu.

achọghị sequela

Ọ bụla ozu dị iche iche na ya onwe ha ụzọ kacha enyi ọgwụ ọjọọ, otú ọbụna enweghị contraindications iji apụtaghị na ị na-adịghị ihe ọ bụla mmetụta. N'oge ọgwụgwọ, ha nwere ike ịbụ ndị na-esonụ jel:

1. Site ụjọ usoro: isi ọwụwa, dizziness, ọdụdọ, migraine, ịda mbà n'obi.
2. Na akụkụ nke obi na ọbara arịa: thrombosis na persistent abawanye na ọbara mgbali.
3. The digestive usoro nwere ike ikwu, ọgbụgbọ, vomiting, afo mgbu, flatulence.
4. Na akụkụ nke omumu usoro nwere ike ime: mmamiri agba ọbara, persistent agbapụta n'ahụ, endometrial proliferation, mgbanwe libido, eriri akpa nwa ahu cancer.
5. The endocrine usoro nwere ike na-egosi ndị na-esonụ mgbaàmà: ntoputa nke ngafe arọ, ara engorgement.

Na ruo ogologo oge ojiji nke jel ọmụmụ ìgwè nwere ike ime ke idem, na-eduga na edema. Nyere na ọgwụ a na-eji topically, nfụkasị rashes, itching nwere ike igosi na akpụkpọ.

Ụfọdụ ọrịa ndị na-eji "Divigel" maka uto nke endometrium, ahapụ ọjọọ nzaghachi n'ihi Ugboro ngosipụta nke mmetụta ndị dị otú ahụ dị ka bịara ikiri ọhụụ na a siri ike mmamiri candidiasis.

Iji zere ihe ọ bụla na-achọghị nsogbu, iji ọgwụ ga-nditịm kenyere onye dọkịta.

Olee otú ga-ewere "Divigel" maka uto nke endometrium

The ọgwụ na ezi tolerability na enweghị contraindications ike ga-eji n'ihi na ogologo oge ọgwụ. Mgbe mbụ ogbo nke ọgwụgwọ, na onunu ogwu bụ 1 g jel. Mgbe ọtụtụ ọmụmụ, ukpụhọde picture, ọrịa, na onunu ogwu nwere ike ụba ma ọ bụ mgbada n'usoro.

Ọ dị mkpa iji chọpụta na dọkịta bụghị naanị ebe iteto "Divigel" maka uto nke endometrium, kamakwa ihe na ụbọchị nke ịhụ nsọ okirikiri ọ dị mkpa ka na-amalite na-eme.

Dị ka nkwupụta, jel ga-na etinyere ọcha akpụkpọ ke ala afo, n'úkwù, afara, ogwe aka ma ọ bụ ike. Na-eme ka ọ na-achọsi ike na otu na otu oge kwa ụbọchị, na ebe nke na ngwa ga-alternated.

The kasị ezigbo ebe maka ngwa atụle size 1-2 ọbụ aka ya. Location nhazi agaghị ekwe omume maka otu awa mgbe ojiji nke jel saa.

Ọ bụrụ na a nwaanyị na-echezọ itinye jel, mgbe ahụ, ọ ga-mere ọ dịghị mgbe e mesịrị ka 12 awa mgbe ngwa nke oge nke ọgwụ. Ọ bụrụ na ọ meela ogologo, ọ dị mkpa ịdị na-eyigharị ya ruo mgbe ọzọ oge.

Ọ bụrụ na ndị dose na-emewokwa

Ọtụtụ ndị kweere na ọ bụrụ na ị na-aṅụ ọgwụ na ibu doses, mmalite nke mmetụta dị mma ga-eme ngwa ngwa, ma nke a abụghị eziokwu. Ndị na-esonụ mgbaàmà nwere ike hụrụ mebiri nke dọkịta na-atụ aro na iji "Divigel" na emewokwa onunu ogwu:

• Soreness na obi.
• Bloating.
• Ntoputa nke nchegbu.
• Mgbakasị.
• Ọgbụgbọ.
• Vomiting.

Mgbe ị na-ahụ ndị a mgbaàmà ga-atụle n'isiokwu na dọkịta gị ma gbanwee dose ma ọ bụ kagbuo na ojiji nke ọgwụ.

"Divigel" na Nchikota na ndị ọrụ ọzọ

Ọ bụrụ na dọkịta na-edepụta "Divigel", jide n'aka na-eji figuring ihe ọgwụ ọrịa na-ewe. Estradiol nwere ndị na-esonụ na-akpata:

• Eme irè nke lipid-ẹsụhọde ọgwụ ọjọọ.
• Imeda mmetụta nke ọgwụ ọjọọ, nke na-agụnye nwoke mmekọahụ homonụ.
• Imeda mmetụta nke ọgwụ ọjọọ eme ihe maka ọrịa shuga.
• Belata ịdị irè nke ọgwụ ọjọọ megide ọbara mgbali.
• Attenuate na ọgwụgwọ mmetụta nke anticoagulants.

Ọ gbapụrụ ọsọ elu metabolism nke estradiol co-ochichi:

• Barbiturates.
• Narcotic analgesics.
• Agents eji maka ná Nkụnwụ.
• Ụfọdụ mgbochi-akwụkwụ ọgwụ ọjọọ.

Arụmọrụ "Divigel" n'ụzọ belata, ma ọ bụrụ na-eji na njikọ na ụfọdụ ọgwụ nje, nakwa dị ka "phenylbutazone". i nwere ike ịkọrọ ya iwere folic acid Mmeju maka thyroid Gland dịkwuo mmetụta.

kpọmkwem na-atụ aro

"Divigel" maka uto nke endometrial nzaghachi dọkịta na-na-mma, ma, ndị ọkachamara nwere ike ikwu na idepụta ya mgbe a nyochaa nke ndidi na zuru ezu okwu na ya.

Iji zere ekwesighi pụta, a nwaanyị ga na-ata a full nnyocha nke pelvic akụkụ na mammary glands. Ọ ga-abụ mgbe nile na ofụri ọgwụgwọ.

Anyị tụlerela, "Divigel" maka uto nke endometrium ebe iteto na ụfọdụ saịtị. Mgbe ahụ, ọ dị mkpa na-asa aka gị na ncha na mmiri na adịghị emetụ anya.

Anaghị emetụta jel na ebe nke thoracic na mmekọahụ glands, nakwa dị ka ebe e iyatesịt. Eji "Divigel" nwere ike igbochi ya na usoro nke ovulation. Njikọ nke homonụ na-adabere na ịta nke estrogen na ọbara, na mgbe ị na-enweta ha si n'èzí, ọ ga-agbajikwa, n'ihi ya, ọgwụ mgbe na-eme atụmatụ a tụụrụ ime ya na-anọchi ihe ókè ịkpachara anya.

Iji ọgwụ n'oge ime na lactation

N'agbanyeghị eziokwu na "Divigel" maka uto nke endometrium reviews IVF akawanye mma, ma ọ bụrụ na ime emee ga-atụle si eme gụkwuo na ya iji na dọkịta gị. Ọ bụrụ na nchoputa nke ihe na-akpali ọnọdụ a nwaanyị bụ na obi abụọ, mgbe ahụ, o yikarịrị, dọkịta ga-eme ka a mkpebi kwụsị iji ọgwụ ọjọọ.

Dị iche iche ọmụmụ na-egosi na onye na-na oge na mgbe ụfọdụ eji jel n'oge ime anaghị eme ka teratogenic mmetụta, ma ihe ize ndụ ahụ ike nke ga-eme n'ọdịnihu na nwa bụ bụghị uru na ya.

Mgbe oge nke ara na-aju iji jel.

Women Health - a na-emebi emebi ihe, o nwere ike falter na kasị ekwesịtụdịghị ekwesị oge. Ọ dịghị onye chọrọ stof gị ahu na ọgwụ, ma e nwere mgbe ị dị nnọọ mkpa a "Divigel" maka uto nke endometrium, reviews, ndị ọzọ ọ na-magburu onwe. Ghaghị mara a ọgwụ bụghị nanị dọkịta ma ọrịa, karịsịa na menopause.

Atụla mehiere icheta otu ugboro ọzọ ka ọgwụ ọ bụla kwesịrị naanị inye a ruru eru ọkachamara, ọ dịghị mkpa ka ndị dị otú ahụ dị oké njọ ọgwụ ọjọọ na ndụmọdụ nke enyi ma ọ bụ hụ mgbasa ozi na telivishọn. Na-elekọta ahụ ike gị!