Fibrinogen - norm na daa ọrịa

Ke ọmụmụ ndị ọbara clotting usoro, a index kpebisiri bụchaghị. Ọ dị mkpa ka dị iche iche ọnọdụ. Tupu ọrụ, a na-akwadebe na-amụ nwa, obi na mkpali oria ọbara mgbe chọpụta fibrinogen. Norma abụghị otu n'ihi na ndị okenye na ụmụ ọhụrụ. N'ihi na ụmụ nwaanyị dị ime, elu ịgba nke ya nnọọ elu. Ma na-eche banyere ụkpụrụ a obere ka e mesịrị. Akpa, ka okwu banyere ihe bụ n'ozuzu na-anọchi anya fibrinogen.

Dị ka ha na chemical Ọdịdị, ọ bụ - na protein. Ọ na-akpọ ihe clotting ihe I. Ọ na-agụnye ikpeazụ ogbo nke ọbara clotting, ya bụ na - na e guzobere a ọbara clot. Na a ike mmadụ fibrinogen na ọbara bụ ugbu ke etisasịwo ala.

N'ihe banyere ebighị nke coagulation usoro na ya nke mbụ ya na ogbo n'okpuru edinam nke ọzọ clotting ihe kpụrụ thrombin.

Na nke abụọ na-adọ n'okpuru nduzi nke clotting fibrinogen na thrombin rapara converted n'ime unyi anaghị agbasa na fibrin, nke Nleta ndabere nke a ọbara clot, a thrombus. Ọ na-agụnye ịkwụsị ọbara ọgbụgba. N'ihi ya ọ na-aghọ doro anya pụtara na ahụ nwere fibrinogen. The norm nke umi nke onye okenye ahụ gbasiri ike kwekọrọ na 2-4 g / l. Na ụmụ a mụrụ ọhụrụ, ọnụego bụ obere - 1,25-3 g / l. Ma, ọ adahade n'oge ime ka 6 g / l. Nke a bụ ihe kwere nghọta. Mgbe niile, a nwanyi ahu na-akwadebe maka na-amụ nwa, nke na-mgbe na-metụtara ọbara ọgbụgba. N'ihi ya, ọ na-enyo, na ọnụego nke fibrinogen n'ime ọbara abụghị otu ihe niile. ọ bụ nnọọ elu ka nwanyị dị ime.

"Ee, ma ebe ọ na-abịa site?" - ị na-ajụ. Ọ na-enyo na a clotting akpata na-emepụta na imeju na-na mkpụrụ ndụ nke reticuloendothelial usoro. Ya mere, na ọrịa imeju, dị ka ịba ọcha n'anya ma ọ bụ imeju arọ fibrinogen onye norm - erughị 2 g / l, mgbe ụfọdụ, na-ebelata ka nnọọ obere nọmba. Nke a nwere ike ime ka a dịgasị iche iche nke agba ọbara, na-agba ọbara na akpụkpọ mucous membranes. Inweta ọgwụ ụfọdụ (androgens, anabolic Steroid) nwekwara belata ya larịị. N'oge ụfọdụ, e nwere ndị pụta ụwa njehie nke muta na-akpata I. Nke a na-akpọ afibrinogenemia ma ọ bụ hypofibrinogenemia.

The nkọ ọnụ nke fibrinogen a hụrụ na abụọ na nke atọ na-adọ dessiminirovannogo intravascular coagulation syndrome. Nke a arọ-enweghị nchịkwa na ọnọdụ, mgbe mgbe, na-agwụcha oké mmiri hemorrhage ruru ka e guzobere obere arịa gbasasịa fibrin egbochi mkpụkọ. Ha bụ nke ukwuu nke na fibrinogen depleting ebuka. Nnukwu fibrinolysis, usoro na-ejikọta ya na ike nke na mgbasa nke fibrin, na-esonyere a ọnụ nke fibrinogen. Ọ mbelata na-adịghị ala ala myeloid leukemia, na a erughi nke vitamin B12 na ahu na S.

Na ọrịa ụfọdụ, na Kama nke ahụ, e nwere ihe mụbara fibrinogen. Norm kasị uru nke coagulating akpata bụ hà 4 g / l. Ma rheumatic, na-efe efe, mgbu Filiks, cancer, thrombosis na infarctions akpata m larịị nwere ike mụbara site 1.5-2.5 ugboro. Fibrinogen a na-akpọ nnukwu-adọ protein, ebe ọ bụ na ya na-abawanye na-esonyere nnukwu mkpali ọrịa. Larịị nke a protein na unan, ojiji, nke ọnụ na gbochie afọ na estrogen mgbe ịwa ahụ.

E nwere ihe àmà gosiri na elu fibrinogen etoju nwere ike ebu ọdịdị ọrịa strok na obi ọgụ. a doro anya na mmekọrịta dị n'etiti ndị a ọrịa na ya gara aga elu larịị a hụrụ na nnyocha.

Iji chọpụta larịị nke fibrinogen, ị ga-agabiga ihe efu afo ọbara a akwara. Ọbara -e n'ime a ule tube na anticoagulant.