Nalidixic acid: Ngwa na Medicine

Ọ maara na bacteria ndị kasị ugboro ugboro pathogens nke mkpali ọrịa na-efe efe. Iji Bibie ozu ha, iji dị iche iche ọgwụ nje. E nwere ọtụtụ dị iche iche nke ọgwụ ọjọọ eme ihe, onye edinam eduzi megide bacteria. One dị otú ahụ bụ nalidixic acid. Ọ bụ n'ọrụ mgwa nke ọtụtụ antibacterial ọgwụ ọjọọ. Otu ihe atụ - a Erere "nevigramon". A ọgwụ bụ nke quinolones, pharmacological otu - antiinfectives. Tupu ị malite ọgwụgwọ, ị ga-gafee ule mata nje na-anwale ya uche na agwọ ọrịa.

Nalidixic acid - ihe ọ bụ?

N'ezie onye ọ bụla bụ maara na preparations nwere nalidixic acid. Nke a ihe onwunwe na-ama-eji ọtụtụ afọ na nkà mmụta ọgwụ dị ka ihe mgbochi-microbial na mgbochi parasitic mmadụ. Nalidixic acid, dị ka e kwuru n'elu, na-ezo aka na ìgwè nke quinolones. Medical isi mmalite iko a bekee na antibacterial ọgwụ ọjọọ. Nalidixic acid bụ a sịntetik ọgwụ na-kere na laabu. Ọ bụ a ìhè edo edo ntụ ntụ, nke na-apụghị igbari na mmiri. The isi ngwa nke acid - a na nkà mmụta ọgwụ. Ọ bụ onye so na ụfọdụ ọgwụ nje.

Action nalidixic acid

Iji mara n'okpuru ihe ọnọdụ ide nalidixic acid, ọ dị mkpa na-amụ usoro nke ya edinam. The isi mmetụta nke ọgwụ - bụ suppression nke ibu nke bacteria na mbibi ha. Ya usoro nke edinam bụ kwụsị DNA njikọ site microorganisms polymerization. nalidixic acid ọgwụ ọjọọ eme ihe bibiri na gram (-) bacteria. Ha na-irè megide microorganisms nke genus Proteus, Escherichia coli. Ya mere, n'igbochi mkpali oria, nke na-kpatara ndị a bacteria.

The edinam nke ọgwụ na-adabere na ya ịta ke idem. Na obere doses, o nwere a bacteriostatic mmetụta, ie, ọ na-egbochi DNA replication. Nnukwu kasịnụ nke ọgwụ na-emetụta na protein njikọ na RNA. Ya mere, ogologo oge ma ọ bụ ochichi nke mbadamba nnukwu doses dapụtara bactericidal edinam. Ọ ga-eti na gram (+) bacteria na anaerobes bụ adịghị emetụ nalidixic acid. Ya mere, tupu ị na-ekenye ya, ị ga-arụrụ bacteriological ule nke ndu ihe onwunwe (mmamịrị, ọbara) na-anọ antibiotikogrammy.

Egosi maka ojiji nke nalidixic acid

E nwere a dịgasị iche iche nke mkpali oria nke etinyere nalidixic acid. Ntuziaka ke ngwugwu na ngwaahịa, na izi ezi nke ihe na nke ya e zigara n'ọrụ umi nke ibute ọrịa. Ma, ọ ga-eburu n'uche na ọrịa ndị a na-bụghị mgbe niile mere site gram (-) na osisi. Ya mere, mgbe adịghị ike nke ndị ọgwụ ga-anọchi ọzọ ọgwụ na 3 ụbọchị. Nnukwu gbasara akụrụ mbufụt - a isi ụdịdị dị iche iche nke ọrịa na nke kenyere nalidixic acid. The ojiji nke ngwaahịa nwere nke a umi, ọ bụ ọsọ bụghị naanị na nephrology, kamakwa ndị ọzọ ubi nke na nkà mmụta ọgwụ. Isi na-egosi - bụ:

1. Cystitis. Mbufụt nke eriri afo esiwak mere site Escherichia coli na Proteus, Otú ọ dị prescribers quinolone enwe a elu nrụpụta megide ndị a microorganisms.
2. Pyelonephritis. Mbufụt nke akụrụ tubules nnọọ emegharị nke ọma ọgwụgwọ na ọgwụ nalidixic acid, karịsịa na nnukwu na-adọ.
3. Diagnosis nke urinary tract-efe efe. Na nke a, ọgwụ ọjọọ na-kenyere ka urological manipulations na arụmọrụ.
4. Nnukwu otitis media.
5. Cholecystitis.
6. Mgbu nnukwu na obere eriri afọ ọrịa (enterocolitis).
7. Urethritis na prostatitis.

Ọzọkwa, nalidixic acid nwere ike ndinọ na ndị ọzọ na-efe efe mere site gram (-) microorganisms.

Gịnị ọgwụ ọjọọ nwere nalidixic acid?

E nwere ọtụtụ ngwaahịa nwere nalidixic acid. Ha niile nwere otu edinam na-egosi maka ojiji. Mgbe ụfọdụ, dị iche iche onunu ogwu nke Isi nọ n'ọrụ umi. Aha dị iche iche na ahịa ndị a ọgwụ ọjọọ eme ihe na-adabere na mba nke rụpụta na ụlọ ọrụ na-emepụta ọgwụ. The kasị ama nnọchiteanya bụ ọgwụ "nevigramon". A ọgwụ nwere ọtụtụ analogues. Otu n'ime ndị a ọgwụ ọjọọ, "Negroes", "Nalid", "Tsistidin", "Vintomilon", "Urogram" na ndị ọzọ. All ndị a ọgwụ ọjọọ nwere a mmetụta yiri na ahu.

Nalidixic acid: ntuziaka maka ojiji nke agwọ ọrịa

Preparations nwere nalidixic acid, ka a na a onunu ogwu nke 500 mg 3-4 ugboro n'ụbọchị. N'ọnọdụ ka ukwuu, a ego nke nọ n'ọrụ mgwa dị na otu mbadamba ma ọ bụ Capsule. Na oké inflammations nwere ike 1000 mg anọ ugboro n'ụbọchị. Na ụmụ, na onunu ogwu ga-gbakọọ (60 mg / n'arọ ahu arọ).

Contraindications na mmetụta

Dị ka ọtụtụ antimicrobials, nalidixic acid a na-contraindicated na ndị inyom na mbụ trimester nke afọ ime na ara. Ọzọkwa, ndị a ọgwụ ọjọọ eme ihe ike ga-eji maka ụmụaka ruo 2 afọ. Tinyere ihe ndị ọzọ contraindications dịpụrụ adịpụ gbasara akụrụ na hepatic insufficiency.

Oghom mmetụta na-agụnye eriri afọ mebiri ọrụ (flatulence, ọgbụgbọ, vomiting), dizziness, na nfụkasị Jeremaya. Anya ga-eji nalidixic acid mmadụ na-ata ahụhụ site na akwara ozi pathologies (ọrịa Parkinson, Akwụkwụ na-adọ, ọrịa strok).