Ọgwụ "Captopril" site na gịnị? Ngwa, reviews, price

Gịnị ka a na ọgwụ ọjọọ, "Captopril", site na nke ọ na-eji na ihe Njirimara? Azịza niile ajụjụ ndị a nwere ike dị na ihe ndị a n'isiokwu a. Ke adianade do, anyị ga-agwa gị banyere otú na-ọgwụ ọjọọ na ihe mmetụta na contraindications iji ya nwere.

General ọmụma banyere ọgwụ ngwaahịa

Drug "Captopril" na Latin na-ada ka "Captopril". A ọgwụ bụ a sịntetik inhibitor nke angiotensin-n'ịtụgharị enzyme (Ace ma ọ bụ abbreviated). Ọ na ọtụtụ-eji ọgwụ na-eme, na ngwa ngwa belata ọbara mgbali.

The mejupụtara nakwa ụdị ọgwụ ntọhapụ

Agwọ ọrịa "captopril" - site na nke ngwá ọrụ e kenyere ya? A, ndị dọkịta ji nye iwu ya maka ndị na-mgbe niile na-ata ahụhụ site na ọbara mgbali. Ọkọnọ ọgwụ a na-eresị naanị n'ụdị a spigot mbadamba na-enịm ke katọn. The n'ọrụ mgwa nke a ọgwụ bụ captopril. Ya ọdịnaya na onye ọ bụla mbadamba bụ 25 ma ọ bụ 50 mg. Otu ngwugwu nwere ike 100, 50, 40, 30, 20 ma ọ bụ 10 iberibe.

The pharmacological edinam nke ọgwụ

Dị ka a tụlere n'elu, "Captopril" mbadamba ntụziaka nke a na-kpara akwụ katọn ahụ, bụ ihe inhibitor nke angiotensin-n'ịtụgharị enzyme (Ace i.e.).

Ọ ga-kwuru na antihypertensive Njirimara nke ọgwụ na-metụtara asọmpi mgbochi nke Ace ọrụ, na-eduga na a ịrịba ọnụ ọnụego akakabarede nke angiotensin 1 angiotensin 2, nke bụ a pụtara nwere ike vasoconstrictive akụrụngwa.

Mgbe a ịrịba ọnụ na ịta nke angiotensin 2 bụ a ọtụtụ ugboro na-abawanye na plasma renin ọrụ site na iwepu ọjọọ nzaghachi mgbe ọ na-tọhapụrụ, ma kpọmkwem Mbelata aldosterone mmepụta. Ke adianade do, agwọ ọrịa "Captopril", analogs nke na-ọkọnọ dịrị gaba n'ime ebe, nwere ike imetụta ndị kallikrein-kinin usoro, si otú na-egbochi mmebi nke bradykinin.

N'ihi na vasodilating mmetụta nke ọgwụ budata ebelata ngụkọta vaskụla eguzogide (elu), capillary nkpirikpi nsogbu na akpa ume vaskụla-eguzogide ha. Ke adianade do, ọ bụ ike dịkwuo nkeji olu nke obi muscle ma na-enwe ndidi.

Ọ bụrụ na ọgwụ "Captopril", reviews nke ndị ọzọ mma, na-a nnọọ ogologo oge, ọ na-egbochi mmepe nke obi ọdịda, ebelata ịdị njọ nke myocardial hypertrophy nke ekpe ventricle, nakwa dị ka onye na-adịghị ala progression nke dilation.

Ke adianade do, agwọ ọrịa bụ ike iji gbochie progression nke ọrịa nephropathy, ẹsụhọde ụda efferent gbasara akụrụ arterioles, na glomeruli budata melite intraglomerular hemodynamics.

Pharmacokinetics nke ọgwụ

Mgbe na-ewere ọgwụ ọjọọ n'obi ya, o ngwa ngwa etinye obi gị dum. Eme a agwọ ọrịa amalite mgbe banyere 40-60 nkeji. The kacha ịta a na-enweta n'ime ahụ mmadụ mgbe mbụ hour.

Ọ ga-kwuru na n'otu oge oriri nke nri ugbu ọgwụ na-ebelata ya absorbability nke 30-40%. Nke a bụ ihe mere mbadamba na-gwara weghara 1 awa tupu a nri ma ọ bụ mgbe 1-1.5 awa ahụ gasịrị.

Duration nke edinam mgbe ojiji nke agwọ ọrịa (iji belata ọbara mgbali) na-adabere na multiplicity nke ya n'ikuku na usoro onunu ogwu. Maka mmepe nke zuru ọgwụgwọ mmetụta a ndidi nwere ike ịchọ ọtụtụ izu nke ọgwụ.

E ji mara na Njirimara nke ọgwụ "Captopril"

Ugbu a, ị mara na bụ ọgwụ "Captopril", site na nke ọ na-eji na-esi mee ihe na mmekọrita ahụ mmadụ. Ma, iji ghọta ihe mere a ọgwụ bụ na-ewu ewu, i kwesịrị ịtụle ya Njirimara.

N'ọrụ umi nke bụ akụkụ nke "Captopril" nkwadebe nwere vasodilating, antihypertensive na cardioprotective Njirimara.

A ọgwụ bụ ike nke na-amụba ntọhapụ nke biologically-arụ ọrụ bekee nwere a natriuretic mmetụta. N'ihi na nke a onwunwe budata mma ọbara na akụrụ ya. Ke adianade do, agwọ ọrịa "Captopril" nke nsogbu na-ebelata ngụkọta post-preload na obi, na-abawanye na gbasara obi mmepụta.

Egosi maka ojiji nke ọgwụ

Ọkọnọ ọgwụ gosiri maka ọgwụgwọ nke na-esonụ abnormalities:

• Ọbara mgbali elu na renovascular. Ọ ga-eji na Nchikota ma ọ bụ dị ka monotherapy.
• Ọrịa nke ekpe ventricle. A, ọgwụ na-eji megide ndị ndị nwere a nkụchi obi ma ugbu a, na clinically anụ ọnọdụ.
• Ọrịa nephropathy. E Kenyere naanị ndị na-arịa ọrịa shuga mbụ ụdị, ie insulin-dabere ndị mmadụ.
• Cardiomyopathy.

Drug "captopril" - si ihe ọzọ na-kenyere a na nkà mmụta ọgwụ? Dị ka a maara, ọgwụ nwere ike ọkọnọ na-eji na mgbagwoju ọgwụ nke obi ọdịda (congestive).

Contraindications na ojiji nke agwọ ọrịa

Dị ka ntụziaka, ọgwụ "Captopril" na-machibidoro iri na ndị na-esonụ mgbe:

• Bụrụ na nke hypersensitivity na-arụsi ọrụ ike mgwa - captopril. Ọ kwesịkwara kwuru na-arụsi ọrụ ike iji ọgwụ na-adịghị na-atụ aro ka ndị nwere ihe omume ekweghị ibe nọrọ na e nwere a doro anya ìgwè nke ọgwụ ọjọọ, nke na-inhibitors nke angiotensin-n'ịtụgharị enzyme (i.e., ọrịa ndị na-mepụtara angionefrotichesky ọkọ n'oge ọgwụgwọ ọzọ Ace inhibitor).
• Mgbe kwuru na ụmụ mmadụ na imeju ọrụ.
• Na cardiogenic ujo.
• Mgbe digestive tract ọrịa.
• Mgbe kwuru na ụmụ mmadụ na akụrụ ọrụ ọnọdụ mgbe transplantation nke ngwa, bilateral stenosis nke akwara, azotemia, hyperkalemia, na isi hyperaldosteronism.
• Ọ bụrụ na hypotension.
• Na immunological ọrịa.
• Mitral stenosis na aortic stenosis.

Ke adianade do, ọgwụ ọjọọ, "Captopril" analogues nke a ọgwụ na-adịghị na-atụ aro ka nwanyị dị ime, ụmụ n'okpuru afọ 18, nakwa dị ka nwa ara na nne.

Drug "Captopril": ntụziaka, na price nke ọgwụ

Dị ka mmasị ntuziaka, ọgwụ kwesịrị iwere banyere 1 awa tupu nri. Na oge nke ọgwụ na onunu ogwu Usoro ọgwụ ọkọnọ ga-kọwaa naanị dibịa n'otu n'otu, na-adabere n'ụdị na eruba n'ime ẹdude ọrịa.

Ya mere, otú na-ọgwụ ọjọọ, "Captopril"? Dose (mbụ) nke agwọ ọrịa na nchoputa nke ọbara mgbali bụ 12.5 mg ugboro abụọ n'ụbọchị. Na nnukwu mkpa maka otu oge ike ga-eji maka nkwadebe nke 2 mbadamba 25 mg. Ma na nke a n'ikuku bụ na-achọsi ike ka a ga-ekewa n'ime 3 ugboro. The kacha kwa ụbọchị dose nke ndị dị otú a agwọ ọrịa bụ 150 mg.

Ọ bụrụ na dọkịta gị edepụtaraghị mmezi ọgwụ ndị a ogologo oge, ọgwụ "Captopril", onye na-agba akaebe na anyị enyocha dị n'elu, ga-akpa mbadamba (25 mg) ugboro atọ ma ọ bụ ugboro abụọ n'ụbọchị.

Mgbe renovascular ọbara mgbali na gbasara akụrụ mbụ onunu ogwu nke agwọ ọrịa bụ 6,25 mg ugboro atọ n'ụbọchị. Aka ọgwụ kwesịrị ịgụnye a 1 mbadamba Nwa (25 mg) ugboro atọ n'ụbọchị.

Ọ bụrụ na ị na-chọpụtara na-adịghị ala ala obi odida na e nwere ụfọdụ n'ime akụrụ, mbụ onunu ogwu kwesịrị 12.5 ma ọ bụ 6,25 mg ugboro atọ n'ụbọchị. N'ihi ya ọ bụla 2-3 izu ga-ada ka ya mmezi dose of 25-50 mg, na otu ugboro. The ndibọbọ usoro postinfarction oge nke agwọ ọrịa yiri.

Ace ìgwè nke ọgwụ ọjọọ na ndị agadi na-kenyere naanị na therapist. Na nke a, na ọgwụgwọ ga-ndị mmadụ. Nabata "Captopril" ndị a ndị mmadụ ga-abụ nke kacha nta dose. Ke adianade do, ọ na-adịghị atụ aro ntọt ofụri ọgwụgwọ. Mgbe oké mkpa, i nwere ike ọzọ na-eji a loop mamịrị.

Ma ihe ndị price, mgbe ahụ, 40 mbadamba nke ngwaahịa a ị ga-akwụ banyere 50-60 Russian rubles. Dị ka ị pụrụ ịhụ, pụtara "Captopril" bụ a dịtụ ego ọgwụ na ihe n'ụzọ dị irè ala ọbara mgbali na a ike.

Iwere na oké ịkpachara anya

Ọkọnọ ọgwụ kwesịrị iwere na oké ịkpachara anya mgbe:

• mgbochi nke ụmị ọkpụkpụ ọbara ekesa;
• oké autoimmune ọrịa;
• arịa ọrịa shuga;
• ọrịa ụbụrụ ischemia ;
• ịrịa ọrịa obi.

mmetụta

Dị ka ntụziaka, mgbe ọgwụ "Captopril" nwere ike ime ná ndị ọrịa na-esonụ n'akụkụ Jeremaya mere:

• bronchospasm, bronchitis, iku ume ọkụ ọkụ, akọrọ-adịghị amị mkpụrụ ụkwara;
• CNS ịda mbà n'obi, isi ọwụwa, ọdụdọ, ataxia, dizziness, tingling ke elu na nke ala na nsọtụ, nakwa dị ka a mmetụta nke nkụnwụ, mgbagwoju anya, na-enwe nsogbu nke isi na ọhụụ, ike ọgwụgwụ, ịda mbà n'obi;
• exfoliative dermatitis, itching, anụ ọkụ ọkụ, photodermatitis, pemphigus, angioedema, urticaria, anaphylactic ujo, na-egbu egbu epidermal necrolysis, alopecia;
• obi n'afọ iri na ụma na-enwe nsogbu, rịaworo pectoris, orthostatic hypotension, myocardial infarction, tachycardia;
• uto nsogbu, flatulence, ọnwụ nke agụụ, stomatitis, ọgbụgbọ, afọ ntachi, glossitis, ọnyá ọnyá nke gastric mucosa na ọnụ, afọ ọsịsa, vomiting, xerostomia, abdominal mgbu;
• paresthesia, ogbu na nkwonkwo, elu neuropathy;
• neutropenia, hyperkalemia, thrombocytopenia, agranulocytosis, eosinophilia;
• oliguria, proteinuria, isi ọrụ nke akụrụ;
• cholestatic ịba ọcha n'anya, pancreatitis, cholestasis, hepatocellular necrosis.

Dị ka Ibọrọ na-ahapụ na-eji ọkụ nke a ọgwụ, mmetụta nwere ike ime ọtụtụ ihe ndị ọzọ ma ọ bụrụ na, mgbe na-ewere ọgwụ na-soro obere nnu ma ọ bụ nnu-free nri.

Drug "Captopril": ovadozu

Na ovadozu data pụtara ọrịa pụrụ igosipụta mmetụta ndị dị otú ahụ dị ka myocardial infarction, na kwupụtara a ngwa ngwa dobe na ọbara mgbali, nnukwu nsogbu nke ọrịa ụbụrụ mgbasa ma na thromboembolic nsogbu.

precautionary jikoro

Dị ka ndị ọkachamara, ọ na-adịghị na-atụ aro na-ọgwụ na potassium-ịhapụ diuretics, na ọgwụ ọjọọ ndị ọzọ na budata dịkwuo ịta nke potassium n'ime ọbara plasma. Ọ bụrụ na anyị na-eleghara a Council, e nwere oké ihe ize ndụ nke hyperkalemia.

Ke adianade do, ọgwụ ọjọọ, "Captopril" ga-eji ihe ókè ịkpachara anya na n'otu oge n'ikuku pụtara "Procainamide", "" allopurinol "," Azathioprine "ma ọ bụ ndị ọzọ immunosuppressants, karịsịa na-anaghị ekwe nke gbasara akụrụ ọrụ.

Na asị ibe connective anụ ahụ ọrịa, nakwa dị ka ala ala obi ọdịda, ọgwụ ekwesịghị naanị iwere n'okpuru nso ọgwụ na ahụ ike na-elekọta.

Ọ kwesịkwara kwuru na, dị ka ọgwụ na ahụ ike ọrịa na reviews, ndị hypotensive mmetụta nke agwọ ọrịa ebelata ọgwụ "Indomethacin" na estrogens.

nchekwa ọnọdụ

Drug "Captopril" na-ezo aka ọgwụ ọjọọ List B. Nke a na ọgwụ a na-wepụtara na-ere ọgwụ ígwè na na ndenye ọgwụ nke dọkịta. Ya adị ndụ bụ 3 afọ si ụbọchị nke rụpụta. Dị otú ahụ nkejikotara ọkacha mma na ọchịchịrị na akọrọ ebe, na okpomọkụ adịghị nnọọ 25 ° C.

ọgwụ analogues

Dị ka nọ n'ọrụ mgwa nwere ndị na-esonụ bughi analogs nke a ọgwụ:

• "Captopril Verein";
• "Angiopril-25";
• "Captopril Acre";
• "Alkadiene";
• "Captopril Sandoz";
• "Vero Captopril";
• "Captopril UBF";
• "Blokordil";
• "Captopril Akos";
• "Captopril hexane";
• "Capoten";
• "Captopril FPO";
• "Captopril SAR";
• "Katopil";
• "Aegis Captopril";
• "Epsitron";
• "Captopril STI."

Dị ka ị na-ahụ, osụk na nkà mmụta ọgwụ nwere nnọọ ole na ole pụrụ iche. Ya mere, ndị ọrịa na-ewelite ajụjụ nke ihe dị mma - ọgwụ "Captopril" ma ọ bụ "Capoten". The isi ihe dị iche n'etiti ha. Ha si dị iche na onye ọ bụla ọzọ na site na emeputa. N'ihi nke a, ọ pụtara "Capoten" bụ uru 3.5 ugboro ọzọ dị oké ọnụ ọgwụ ọjọọ, "Captopril".

Nyocha nkwadebe

N'agbanyeghị ala price, na agwọ ọrịa "Captopril" irè lowers ọbara mgbali. Ọrịa ndị na-ugboro ugboro-eji nke a ọgwụ na-ekwu na mmetụta ya na-apụta ìhè n'ime 1-3 awa mgbe ingestion.

Onye nfụkasị Jeremaya mgbe ngwa nke gị n'ụlọnga eme banyere 5-8% nke ndị mmadụ. Ọtụtụ na-ekwu na a ọgwụ na-akpata oké ọzịza. Ọ bụ ya mere tupu iji, jide n'aka na ịkpọ dọkịta gị. Ọ bụrụ na ndị isi "Captopril" bụ dịkarịa ala otu akụkụ mmetụta, ọ na-achọsi ike na-ajụ ya ma na-aga na a na-agwọ ya maka ọbara mgbali elu si ọzọ ìgwè.

E nwere nnọọ ọtụtụ nke reviews na "Captopril" ọgwụ "Capoten" na ndị ọzọ analogues ndị a ego n'ụzọ dị irè na-enyere tufuo ọbara mgbali agadi. Ma tupu ndị dị otú ahụ a na Usoro, jide n'aka na ịkpọ dọkịta gị. Ke adianade do, onye na agadi iji kpochapụ ọbara mgbali elu na ọrịa ndị ọzọ na-atụ aro iji naanị kasị ala dose ọgwụ.

Ọ dị mma na-eji ọgwụ ọjọọ?

Na ndabere nke na mpaghara ụlọ ọgwụ dị na Rivne (Ukraine) na 2010, a E duziri ọmụmụ ugboro ole nke mmetụta si ewere ọgwụ "Captopril". Na a usoro, gara site na ndị mmadụ na-nwayọọ na agafeghị oke ọbara mgbali elu. N'ihi ya, nke 500 na-achị mere mkpesa nke mmetụta naanị 73 ndị mmadụ. N'ime ndị a, 53 - kwụsị ịṅụ ọgwụ ọjọọ, ma ndị fọdụrụ 20 - aka iso, dị ka ha hụrụ na ọ na-eweta a otutu ihe ọma karịa nsogbu ahụ ike.