Ọgwụ "Gynestril": ntuziaka maka ojiji, analogs na reviews

Olee na-ọgwụ ọjọọ, "Gynestril"? Ntuziaka maka iji nke a na nkà mmụta ọgwụ ga-kọwara na ihe ndị a n'isiokwu a. Na ya, anyị na-ewetara Ibọrọ nke ọrịa, ọgwụ, ya pharmacological àgwà, na-egosi na contraindications.

The mejupụtara, udi

Gịnị mmiri na-agụnye ọgwụ "Gynestril"? The Regulations weghaara ka nke a pụtara, ọ bụ na ya nọ n'ọrụ mgwa bụ mifepristone. Ọzọkwa na agwọ ọrịa mejupụtara ọzọ Efrata n'ụdị nduku starch, lactose, microcrystalline cellulose, povidone, magnesium stearate na sodium carboxymethyl starch.

Zụrụ a ọgwụ nwere ike ịbụ na mbadamba, nke na-packaged ke Ukwu nke kaadiboodu.

Pharmacological e ji mara ọgwụ

Ị maara na bụ ọgwụ "Gynestril"? Ntuziaka maka ojiji ga-enyere gị aka ịghọta ụkpụrụ nke ihe nke a ọgwụ, na ga-agwa gị na ọ bụghị na-egosi nke ya ojiji na ọgwụ na ahụ ike omume.

E lee ya anya agwọ ọrịa bụ a steroid gị n'ụlọnga antigestagens bụghị. The ọgwụgwọ nrụpụta ọrụ nke ọgwụ ruru ya mejupụtara.

N'elu nnata nke mifepristone n'ime ahụ mmadụ ọ na-egbochi mmetụta nke progesterone, ma ọ dịghị igosipụta progestational ọrụ.

Ndị ọkachamara kwuru na adomokoro nke ọgwụ n'ihi mpi glucocorticoid nkịtị na ihe nnabata larịị.

Dị ka a maara, isi ọrụ ke guzobere eriri akpa nwa leiomyoma nyere nwaanyị homonụ, karịsịa progesterone. Na nke a, mifepristone nwere ike kenyere a ndidi igbochi progesterone ihe nnabata. Dị ka a N'ihi nke a ọgwụgwọ na-ewe ebe akpụ ibu na-egbu oge, nakwa dị ka mbenata size of fibroids , na eriri akpa nwa.

The pharmacokinetic Njirimara nke ọgwụ

Olee ihe nwere pharmacokinetic ọgwụ "Gynestril"? Ntuziaka, reviews nwetara na dọkịta ekwuo na mgbe onu ochichi kasị elu ịta nke ọgwụ na-hụrụ banyere 80 nkeji. Ọzọkwa, ya bioavailability bụ 69%.

Plasma na-edozi na-ewere ọgwụ na-ejikọ na 98% (na albumin na Alfa-1 acid glycoprotein).

Mgbe nkesa na-adọ na-adị ngwa ngwa iwepụ na-adọ. Na ọbara ịta nke ọgwụ na-belata ọkara (n'etiti 15 na awa 72).

Mkpochapu ọgwụ bụ ngwa ngwa, na a oge nke 18 awa.

egosi

Site na nke ọgwụ ọjọọ, "Gynestril" nwere ike na-kenyere? Ntuziaka maka ojiji, ezigbo ndị ọkachamara na-atụ aro ndị na-esonụ na-egosi:

• ọgwụgwọ nke eriri akpa nwa leiomyoma;
• nchupu intrauterine ime ruo 42 ụbọchị;
• itinye n'ọkwa (ma ọ bụ mmalite) nke oru (gụnyere na okwu);
• mberede igbochi afọ (postcoital) maka unreliability eji ogwu, na oge mgbe unprotected mmekọahụ.

contraindications

"Gynestril" ọgwụ maka ite ime na-ekwesịghị-eji mgbe:

• clinically unconfirmed ime;
• ime ectopic ime;
• ime nke bilie mgbe ndọrọ ego nke mmiri ọgwụ ogwu n'aka, ma ọ bụ site na iji ihe intrauterine ogwu;
• ime mgbe 42 ụbọchị.

Mgbe leiomyoma a ọgwụ na-aju ekenye ndị na-esonụ mgbe:

• ịtụkwasị na submucous myoma ọnụ;
• na ovarian etuto ahụ;
• endometrial hyperplasia;
• ma ọ bụrụ na leiomyoma uru bụ nnukwu.

"Gynestril" Mbadamba maka itinye n'ọkwa nke oru na-adịghị eji na:

• oké preeclampsia;
• ndiiche nwa ebu n'afọ na ngosi;
• tupu eclampsia;
• eclampsia;
• preterm ma ọ bụ post-okwu dị ime;
• imbalances size nke nwa ebu n'afọ na isi nne na pelvis;
• undiagnosed spotting si Genital tract n'oge gestation.

Ò general contraindications ọgwụ "Gynestril"? Ntuziaka enye ajụjụ a kemkwenye. Ndị a machibidoro iwu na-agụnye ndị na-esonụ ọnọdụ:

• porphyria;
• ogologo oge ọgwụ na glucocorticoids;
• oké anaemia;
• gbasara akụrụ ma ọ bụ mmebi imeju (n'ụdị ọ bụla);
• mebiri hemostasis (gara aga anticoagulant ọgwụgwọ);
• extragenital oké njọ okike;
• daa ọrịa nke nwanyi omumu usoro, nke bụ ihe mgbu agwa;
• hypersensitivity (gụnyere akụkọ ihe mere eme);
• nikotinozavisimost, karịsịa mgbe afọ nke 35.

Ihe ókè ịkpachara anya mgbe aṅụ ọgwụ a:

• okpo akpa ume ọrịa na (adịghị ala ala agwa);
• obi odida;
• ọbara mgbali;
• arrhythmia;
• bronchial ụkwara ume ọkụ;
• obi n'afọ iri na ụma disturbances.

Drug "Gynestril": okwu

N'ihi na nchupu nke afọ ime (ndidi reviews nke agwọ ọrịa ga-atụle a bit n'ihu), a ọgwụ kwesịrị inye naanị a warara ọkachamara. Na na-na-ewere mbadamba nkume ndị a naanị na ọnụnọ nke a ọkachamara n'ọrịa ụmụ nwanyị.

Ebe ọ bụ na ọgwụ ọjọọ "Gynestril"? Ntuziaka maka ime nchupu na-ekwu na ọ dị mkpa iji otu dose nke 600 mg.

The ọgwụ na-adia 1-1.5 awa mgbe nri na asa ala na 100 ml mmiri.

Dịkwuo nrụpụta nke ọgwụ nwere ike n'ihu nzube 400 mg misoprostol (i.e., a sịntetik prostaglandin E1).

Mgbe anata mbadamba ndidi ga-chịkwara obstetrician dịkarịa ala awa abụọ. Mgbe 1.5 ụbọchị ma ọ bụ 2 rụrụ ultrasound. Ọbụna mgbe 1-2 izu kụziere ndị na-adakarị nnyocha na ugboro ugboro ultrasound na-elele ọbara etoju nke HCG iji gosi a ime ọpụpụ.

Na ikpe, ma ọ bụrụ na ọgwụ ọ bụghị aka (ie, afọ ime na-aga n'ihu), dọkịta na-atụ aro a agụụ ọchịchọ n'ihu ọmụmụ (histology) pụta nke usoro.

Na-akpali ndị ọnyà eme, ọgwụ ozugbo ndinọ na a onunu ogwu nke 200 mg. Ha na-eme nke a na ọnụnọ nke a ọkachamara n'ọrịa ụmụ nwanyị. Mgbe otu ụbọchị, ndị dose nke ọgwụ na-ugboro ugboro n'otu dose.

Mgbe 2-3 ụbọchị, na-eme atụmatụ mgbasa nke ọmụmụ kanaal. N'ihi ya ikpebi ekwe omume nke n'ihu eji "Oxytocin" ma ọ bụ prostaglandins.

Ma eriri akpa nwa leiomyoma ọgwụ ọjọọ "Gynestril"? Guide na-ekwu na mgbe ndị dị otú ahụ nchoputa nkwadebe na-emekarị ndinọ na a otu dose of 50 mg. Ọgwụ e ji ọnụ na ọnwa atọ.

Banyere post-coital igbochi afọ, ndị dọkịta nwere ike ikwu na ojiji nke na-atụle agwọ ọrịa ke ichekwa 10 mg maka ụbọchị atọ mgbe unprotected mmekọahụ (n'agbanyeghị ịhụ nsọ na-adọ). Inweta ọgwụ na nke a na ọ na-achọsi ike ruo awa abụọ tupu ma ọ bụ mgbe nri.

ikpe nke ovadozu

Jiri nke ọgwụ na a dose nke ọ bụla karịrị abụọ grams nke na-akpata nke ọ bụla mmetụta ọjọọ. Mgbe na-eji ihe karịrị kpọmkwem ego nke ọgwụ a ndidi nwere ike na-etolite adrenal insufficiency, nke na-achọ symptomatic ọgwụ.

mmetụta

Ịnata agwọ ọrịa "Gynestril" na-akpatakarị dị otú ahụ mmetụta dị ka isi ọwụwa, ọgbụgbọ, dizziness, vomiting, ihe ọkụ ọkụ, afọ ọsịsa, amenorrhea, lohiometra spotting, eriri akpa nwa subinvoljutcija, hyperthermia, emmeniopathy, adịghị ike, ịda mbà n'obi nke mbufụt nke akpanwa na ejiji, erughị ala na ihe mgbu na afo. Ọ bụrụ na ị na-enwe ndị a mgbaàmà, jide n'aka na ịkpọ onye dọkịta.

ọgwụ interactions

Ọ na-adịghị na-atụ aro na-ọgwụ ọjọọ, "Gynestril" ke ukem na NSAIDs. Ọ kwesịkwara kwuru na na Nchikota na glucocorticoids dị mkpa ka iwelie dose, ma naanị mgbe n'ịgakwuru dọkịta gị.

kpọmkwem na-atụ aro

Ọ na-adịghị atụ aro iji na-na nkà mmụta ọgwụ dị ka a mgbe nile ogwu.

Mgbe ị na-eji "Gynestril" Ime mgbe niile kwesịrị agwa onye ọrịa banyere ndị ọzọ nhọrọ nke a usoro, karịsịa ma ọ bụrụ mgbe izu abụọ nke afọ ime na-aga n'ihu ma ọ bụ na e nwere onye na-ezughị ezu ime na (na o kwere omume ize ndụ nke abnormalities na nwa ebu n'afọ).

Price na analogues ego

Analogs "Gynestril nlekọta" nke ọgwụ ndị na-esonụ ọgwụ: "Ginepriston", "Penkrofton", "Agesta" "Mifepristone", "Zhenale", "Mifolian", "Mifegin", "Mifepreks", "Miropriston".

Price atụle ọgwụ ọjọọ dị nnọọ elu na ana 5000-6000 rubles.

Nyocha nke agwọ ọrịa

Doro nnọọ anya na kpọmkwem ebughi comments banyere "Gynestril" ọ dịghị nkwadebe. Ma, ọtụtụ ndị ọrịa nabatara banyere ngwá ọrụ a. Ha na-ekwu na ọ bụ nnọọ irè na mma maka n'ikuku.

Ọ kwesịkwara kwuru na ụfọdụ ndị mmadụ, na Kama nke ahụ, na-emekarị hụrụ na mmepe nke mmetụta.

All ndị a reviews-atụ aro na oriri nke a ọgwụ ga-eme nanị mgbe oge na dọkịta.