Uric acid: ya ọnụego ke idem

Otu n'ime ihe ndị dị mkpa ọcha bụ purine bases na-akụkụ nke mmadụ DNA na RNA (ribonucleic acid na deoxyribonucleic mara akwụkwọ) maka kwesịrị ịrụ ọrụ nke ahu. Ugbu a, anyị agaghị na-aga n'ime n'ụlọ akwụkwọ na-akọwa onye ọ bụla umi - otu page bụ ezughị, anyị ga-eji nkenke oge na-akọwa na ndị a mgbagwoju organic asịd ịrụ nyefe nke mkpụrụ ndụ ihe nketa koodu na-abuana ke protein njikọ.

Nke a bụ iji na-aghọta mkpa nke ọrụ organic ogige - enweghị ịdị adị nke purines bụ omume ka ewere ndụ nke agbụrụ ụmụ mmadụ dị ka a ndu bi. The decomposition na njikọ nke a substrates - mgbe nile Biochemical Jeremaya mere na-ewere ọnọdụ na ahụ nke ọ bụla otu onye n'ụwa. Anyị imeju emee oge purine metabolism, na ngwaahịa ndị a Filiks bụ uric acid. The norm nke acid àmà site 0,35 mm.

Nke a umi e mbụ chọpụtara na ndu ọmụmụ, nke mere na ọ nwetara aha ya. Mgbe gbasara akụrụ uric acid anyụpụ si ahụ, na-ebelata ya nke ngafe nitrogen nke di na ọtụtụ akụkụ: obi, imeju, na ụbụrụ. Na plasma a acid a na-ekesa na ụdị sodium urate, ọ na-adabere na ịta larịị nke microcell. Mgbe ego nke sodium urate ọbara uric acid kwukwara karị. The norm nke ọdịnaya, ka nke a ga-gafere 0,35 mmol (kwa liter ọbara).

Ọ bụrụ na nke a oke na-ụba, e nwere deposition nke crystallized urate na anụ ahụ nke ahụ. N'eziokwu larịị nke a acid ịta na ọbara na-adịghị anya ya crystallization fọrọ, si otú amụba ya nwetụrụ omume akpasu siri ike ịkpali - mesịakwa ọ debe anyị ahu.

E nwere ọtụtụ dị iche iche ihe ndị na-eduga na ụba ọdịnaya nke urate, ọ pụrụ ịbụ a nri ọgaranya organic bases, ọbara, akụrụ, obi na cancer na anabata Filiks, na ọbụna a ike ụtụtụ ọrịa n'oge ime. Ọtụtụ mgbe isi na-akpata urate deposition nke uric acid ka bụ ịṅụ mmanya na-aba n'anya. Kristal pụrụ kpụrụ niile esịtidem akụkụ, ma ọtụtụ mgbe, ha na-edebe na nkwonkwo. Ha guzobere na-eme ọrịa ndị dị ka gout.

Mgbe Ịchọpụta Otú Nsogbu a onye nwere gout na akpa ebe e debere ezi ihe kpatara nke ọrịa. Nke a ga-bụghị naanị ekwe ọgwụgwọ kwesịrị ekwesị, ma na-chọpụta ọnụnọ nke ọrịa ndị ọzọ, nke nwere ike na-eje ozi dị ka a akpalite maka omume nke gout. On isi gout ịrịba ama na-egosi ndị na-esonụ: na-abawanye nke uric acid njikọ ma ọ bụ excretion ya mkpụmkpụ.

Secondary gout na-chọpụtara site ọnụnọ nke ọzọ ọrịa - ọnụego nke uric acid n'ime ọbara na ụdị nile nke ọrịa ga-amụba. Mesoo, ọ bụ nke mbụ dị mkpa ọ bụghị nanị nkwonkwo, nakwa dị ka na-elekwasị anya nke mbufụt - gout mgbe irè ọgwụ ga-apụ n'anya na ha onwe ha. Ma na mgbakwunye na gout nwere ike iputa urolithiasis, nke na-ebilite ke ikpe mgbe ahụ uric acid ụtụtụ. Norma urate plasma sharply enwekwu na-eduga ná ọrịa.

N'otu oge ahụ na eriri afo ma ọ bụ akụrụ ekara siri ike ọdịda, mgbe mgbe, na-eduga na urinary njigide. Ndị a concretions nwere ike a na-akpata mkpali nsogbu na pụrụ ọbụna imebi elu nke esịtidem akụkụ nke ha na-emi odude. The na-achọpụta ọrịa uru a na-ebelata uric acid. ya ọnụego ekwesịghị ịbụ n'okpuru 0,15 mm.

The ala ịta nke uric acid nwere ike na-egosi na ọnụnọ nke enwetara ma ọ bụ ketara ọrịa. Mgbe achọpụtara na plasma nke na-abụghị nnabata udu nke uric acid kwesịrị, na mbụ, inyocha nri, ewepu kọfị, na mmanya, chocolate, na-agụnye ke menu nke ọhụrụ na akwụkwọ nri (akwụkwọ nri, radishes, asparagus).