Adenovirus (adenovirus) - ihe ọ bụ? Olee otú na-emeso adenovirus?

E nwere ọtụtụ na-efe efe na nwere ike ime ka ọrịa dị iche iche na ụmụ mmadụ. Otu n'ime ha a pụrụ iche n'ebe a na-ji site adenovirus. Olee ụdị microorganism, nke akụkụ ọ na-emetụta, otú ya ọgụ? Ọtụtụ ndị mmadụ nụrụ nke ndị dị otú a causative gị n'ụlọnga.

Adenovirus - ụdị organism?

The ọrịa bụ ndị ezinụlọ adenovirus ochie mastadenoviruses. Ugbu a, e nwere ihe iri anọ serotypes. Dị ka akụkụ nke ọ bụla nke virus nwere DNA molekul na-atụle ga-a akụkụ pụrụ iche nke ndị ọzọ akụkụ okuku ume na-anọchite anya.

Ọ na-ike na adenoviruses - a microorganism * Tụkwasị na udi na a dayameta nke 70-90 nm. O nwere a dị mfe nzukọ.

pathogens na-akpa kewapụrụ tonsils na adenoids na-arịa ọrịa na nwa ke 1953. Gasịrị, mgbe iteto Microscopy na ọrịa na nnukwu akụkụ okuku ume malitere ịrịa ọrịa na-achọta adenovirus. Gịnị bụ nke a omimi ọrịa? Ma, ọ na-ekpughe, na ọrịa na mgbaàmà nke gbara gharịị oyi baa na mmepe nke conjunctivitis.

Olee otú ọ na-ebute site ná

Nje malitere ịrịa nje nwere ike airborne na Nsị-onu ụzọ, site na onye ọrịa ihe, nri, mmiri na-emeghe mmiri ma ọ bụ na igwu ọdọ mmiri. Adenovirus - bụ ọrịa na-akpali dị ka a onye na ẹdude mgbaàmà, na virus ụgbọelu, adịghị ihe ọ bụla ihe ịrịba ama nke ọrịa.

The ọrịa bụ eguzogide gburugburu ebe obibi mgbanwe, na-adịghị ebibi ikuku na mmiri na-adịgide ruo ogologo oge na ọgwụgwọ na-eji maka ọgwụgwọ na ophthalmology.

The ebe iwebata nke virus bụ mucous membranes nke akụkụ okuku ume na digestive usoro, conjunctiva. Abami n'ime epithelial mkpụrụ ndụ na Lymph, ọ na-amalite na ọtụtụ. Ọ bụ mmepe nke CPE na guzobe intranuclear inclusions. Na-emetụta mkpụrụ ndụ na-ebibi ma na-ala n'iyi, na virus migrates ala n'ọbara, ibunye ndị ọzọ akụkụ.

N'etiti ụfọdụ adenoviral serotypes okosobode oncogenic nnochite anya, na-eme ka e guzobere ịza aza etuto ahụ na ụmụ anụmanụ.

Dị ka a n'ihi nke adenovirus ọrịa epithelial anụ ahụ ka a nta ruo n'ókè ihe mgbochi ọrụ, nke na-ebelata dịghịzi ndu Jeremaya mere na ahu na nwere ike ime ka a concomitant mmepe nke nje na mbibi. Ọ na-adịghị nwere a pathogenic mmetụta ụmụ anụmanụ.

Nchedo re-ọrịa

Abụkarị ọrịa na-agbake site na adenovirus ọrịa, mepụtara a siri ike ọgụ, kama ọ bụ naanị na a kpọmkwem serotype adenovirus. Gịnị ka ọ pụtara? Ọ na-enyo na n'oge ụdi kọntaktị na a kpọmkwem virus na-adịghị na-arịa ọrịa ndị mmadụ.

Na mụọ nwa, nwa-enweta n'ezinụlọ ọgụ, nke kpamkpam mgbe ọnwa isii.

Iche adenoviral ọrịa

E nwere ma random na ọrịa ngosipụta nke adenoviruses, ihe ka ọtụtụ n'ime ụmụ otu. The ọrịa e ji a dịgasị iche iche nke ngosipụta, dị ka nje na-emetụta akụkụ okuku ume na usoro, mucous membranes, anya, eriri afọ, eriri afo.

Dị iche iche mmetụta na mmadụ adenoviruses. Nhazi ọkwa ọrịa na-agụnye:

• nnukwu akụkụ okuku ume malitere ịrịa ọrịa na Nchikota na fever (na-emekarị na-amalite na nwata);
• nnukwu akụkụ okuku ume malitere ịrịa ọrịa ịghọ okenye;
• malitere ịrịa ka oyi baa;
• nnukwu adenoviral rịaworo (karịsịa nkịtị ke ụmụaka n'oge okpomọkụ mgbe mmiri omume);
• pharyngoconjunctival fever;
• plonchaty conjunctivitis;
• mesadenitis;
• nnukwu follicular conjunctivitis;
• okenye ọrịa keratoconjunctivitis;
• nsia ọrịa (enteritis, malitere ịrịa afọ ọsịsa, gastroenteritis).

Na oge nke incubation oge si atọ ka ụbọchị itoolu.

njupụta nke ọrịa

N'etiti ihe niile e dere na-efe efe nke akụkụ okuku ume na usoro na a nta nke ndị adenoviral meriri akụkọ ihe n'etiti 2 to 5%. The kasị o kpughere mụrụ ọhụrụ na ụmụaka.

Si 5 na 10% nke malitere ịrịa ọdịdị nke ọrịa akaụntụ maka adenovirus. Gịnị ka nke na-egosi? Mbụ, eziokwu ndị a na-agba akaebe ya, obosara-ekesa, karịsịa na nwata (75%). N'ime ndị a, ruo 40% n'akparamagwa ụmụ n'okpuru 5 afọ, ma ndị fọdụrụ percentages na-ekesa n'agbata afọ 5 na afọ 14.

Adenoviral ọrịa nke akụkụ okuku ume na agwa

Malite ọrịa fever ruo 39 ° C, isi ọwụwa na izugbe malaise. Na ụmụaka dị iche iche na-eme adenovirus, mgbaàmà na-egosi nwayọọ nwayọọ na ụmụ ha, ha na-ji lethargy, enweghị agụụ, ala-ọkwa ahu okpomọkụ.

Ahụ ọkụ na-ewe ihe ruo ụbọchị iri. Ahu okpomọkụ pụrụ mgbe ahụ na-ada, mgbe ahụ ebili ọzọ, ọhụrụ mgbaàmà na-dere n'oge a.

Site n'ụbọchị ndị mbụ nke ọrịa na e dịghị òkè mkpọchi. N'echi bụ ukwuu mucous ma ọ bụ mucopurulent agbapụta n'ahụ, Bilie akọrọ ụkwara ime ugboro ugboro.

Ọ na-amalite na-afụ ụfụ ya akpịrị n'ihi nācha ọbara-ọbara nke akpịrị, tonsils na arches, akpatre na-abawanye na size.

Ịrịba ama nke airway mbufụt

Nke a na ụdị bụ ihe kasị nkịtị, ọ e ji mbufụt na karị. The isi ọrịa na-agụnye laryngitis, rhinopharyngitis, tracheitis, bronchitis na-agafeghị oke general igbu egbu.

Ịrịba ama pharyngoconjunctival fever

Ezighị ezi mmetụta na akpịrị nwere adenovirus. Mgbaàmà bụ n'ihi na-abawanye na mmeghachi omume okpomọkụ izu abụọ na mgbaàmà nke pharyngitis. Na-emekarị na e nwere a akpịrị na akpịrị na mgbe ụfọdụ agụụ ụkwara, na ọrịa anaghị agabigaghị akụkụ okuku ume na tract.

Mgbaàmà nke conjunctivitis plonchatogo

Kasị ata ahụhụ site na ndị okenye na ụmụaka na-eto eto. The ọrịa e mere site unilateral ma ọ bụ bilateral conjunctivitis na guzobere a film na mucosa nke ala nkuchianaya. E nwekwara a nnọọ ọkọ na nācha ọbara-ọbara nke anụ ahụ gburugburu anya, ihe mgbu, mụbara vaskụla bed na conjunctiva na fever. Na ọrịa a na akụkụ okuku ume na usoro dịghị infestation adenoviral ọrịa.

ịrịba ama tonsillopharyngitis

The ọrịa amalite na ụmụaka ụlọ akwụkwọ ọta akara afọ. A mara mma nke tonsillopharyngitis bụ mkpali mgbanwe ákwà akpụ pharynx na tonsils. Adenovirus, a foto nke a na-nyere n'okpuru ebe a, bụ ihe kpatara nke rịaworo.

Iche nsia forms

Ediyarade nke adenovirus ọrịa ke gootu jikọtara mmepe nke a agafeghị oke malitere ịrịa afọ ọsịsa na gastroenteritis. The virus na-akpata ọgbụgbọ, vomiting, afọ ọsịsa, enweghị adịghị ọcha, a nta na-abawanye na ahu okpomọkụ. Ke adianade nsia ọrịa na o kwere omume ọrịa nke akụkụ okuku ume na usoro, n'ihi na ihe atụ, rhinopharyngitis ma ọ bụ laryngotracheitis.

mesenteric adenitis

Ụdị ọzọ nke ọrịa, bụ nke abdominal mgbu na fever. Ọ bụ omume concomitant ọrịa nje na-achọ antimicrobial ọgwụ.

Olee otú ịmata ihe causative gị n'ụlọnga

E nwere kpọmkwem ụzọ nke adenoviruses kpebisiri ike. Microbiology eji dị ka ule na nsị ihe n'ahụ si gọzie gị amaokwu, akpịrị, anya conjunctiva. Iji guzosie pathogen Inoculation na-eji, nke a rụrụ na a omenala mmadụ epithelial mkpụrụ ndụ.

The laabu nchoputa iji immunofluorescence Microscopy ịchọpụta abụkwara on adenoviruses. Microbiology ya ngwá nwere ọtụtụ usoro ndị nwere ike ikpebi nke a bu oria. A na-agụnye ụzọ maka:

• RAC - serodiagnosis malitere ịrịa nje ruru ka zuo ezu-antibody mmeghachi omume IgG na IgM.
• Hai - Haemagglutination mmeghachi omume a na-ewere braking usoro maka njirimara nke virus ma ọ bụ-alụso ọrịa ọgụ na ọrịa ọbara plasma. Method na-arụ ọrụ site n'igbochi na malitere ịrịa abụkwara si dịghịzi ọbara-alụso ọrịa ọgụ mgbe nke furu efu ike nke nje ka agglutinate erythrocytic mkpụrụ ndụ.
• RN-usoro dabeere na mbenata cytopathic mmetụta nke virus dị ka a N'ihi nke na njikọ na kpọmkwem AT.

Iji chọpụta malitere ịrịa antigen nwere ike ịbụ site n'aka ngwa ngwa nchoputa. A ọ na-agụnye ndị dị otú ahụ nnyocha:

• Immunoassay analysis ma ọ bụ ELISA - laabu usoro immunological mkpebi siri ike nke qualitative ma ọ bụ quantitative e ji mara nke virus, dabeere na a kpọmkwem mmeghachi omume n'etiti antigen na ihe antibody;
• immunofluorescence mmeghachi omume, ma ọ bụ RIF, nke na-enye ohere nchọpụta nke-alụso ọrịa ọgụ na adenovirus ọrịa (ma ọ bụrụ na usoro a na-eji iteto, prestained e ji esiji ákwà);
• Analysis radioimmunoassay, Ria ma ọ bụ na-enyere tụọ ọ bụla ịta nke virus na ọmụmụ.

Olee otú agha ọrịa

Mgbe oruru nke ọma chọpụta tupu dọkịta na onye ọrịa bụ ajụjụ nke isi na-emeso adenovirus. Ọ na-kweere na kpọmkwem ọgwụ ọjọọ na-adịghị ugbu a na-adị.

Dabere na ogo nwere ike mere n'ụlọ na dọkịta gị ọgwụgwọ nke ọrịa ma ọ bụ na ndị ụlọ ọgwụ. Anaghị achọ ụlọ ọgwụ nwayọọ na agafeghị oke iche nke ọrịa, bụ uneventful. Siri ike ikpe ma ọ bụ nsogbu a ga-emeso na ụlọ ọgwụ n'okpuru nlekọta nke a dibịa.

Iji merie adenovirus ọgwụgwọ nke nwayọọ forms na-ebelata ka bed ike. Na ahu okpomọkụ n'elu 38 ° C paracetamol ndinọ na a dose nke 0,2 na 0.4 g nke 2 ma ọ bụ 3 ugboro n'ụbọchị, nke kwekọrọ na 10 ma ọ bụ 15 mg kwa 1 n'arọ nke ahu arọ kwa ụbọchị. Site adenoviral ọrịa ejighị acetylsalicylic acid.

Dabere na ụdị ọrịa symptomatic ọgwụgwọ antitussive, expectorant elekọta mmadụ nwere ike gwọọ "Stoptussinom" "glaucine," "Glauventom" "Mukaltin".

The inhalation aerosol were deoxyribonuclease. Ha na-2 ma ọ bụ ugboro 3 a ụbọchị 15 nkeji. Rhinitis kụnyere pụrụ iche imi tụlee.

Iji na-akwalite ọgụ iji vitamin okụre na amanyere bụ iwu nke ọdịnaya nke ascorbic acid, tocopherol, rutin, thiamine na riboflavin.

Ọ bụrụ na gburu anya adenovirus ọgwụgwọ a na-ebu ụmụ irighiri mmiri deoxyribonuclease enzyme na a 0.1- ma ọ bụ 0,2% ngwọta ọ bụla awa 2 na 3 tụlee. The dibịa nwere ike nye iwu ka Nde ọgwụgwọ nke conjunctivitis glucocorticoid ointments, interferon preparations, anya ointments na antiviral ma ọ bụ oxoline tebrofenom.

nchedo ọrịa

Iji gbochie adenovirus ọrịa ma belata omume nke nnukwu akụkụ okuku ume malitere ịrịa ọrịa na-eji ịgba ọgwụ mgbochi ọrịa na ndụ vaccines, nke gunyere attenuated malitere ịrịa mkpụrụ ndụ nke kasịnụ serotype.

Ejikarị ọgwụ ọjọọ eme ihe na adenovirus ụdị 4 ma ọ bụ 7 na-echebe ha si eriri afọ mgbaze pụrụ iche ntekwasa Capsule.

E nwere ndị ọzọ ọgwụ mgbochi na a ndụ na inactivated iche-iche, ma ha na-adịghị eji n'ihi na oncogenic ọrụ nke adenoviruses.