"Finoptinum": ntuziaka maka ojiji, mejupụtara, n'ezie na ogbo

Si obi na vaskụla ọrịa na-emetụta ọtụtụ ndị mmadụ. Ọzọkwa, na afọ, ihe ize ndụ nke dị otú ahụ na ọrịa na-ekwu na-ukwuu ụba. Iji belata ihe ize ndụ nke oké njọ Filiks ke idem, ndị dọkịta nwere ike ikwu na ojiji nke pụrụ iche ngwaọrụ. N'etiti ha bụ ndị karịsịa na-ewu ewu na- calcium ọwa blockers. Ha na-a heterogeneous ìgwè nke ọgwụ ọjọọ. Ha usoro nke edinam jikọtara ike inhibit penetration nke calcium ion si extracellular ohere na mkpụrụ ndụ na ọbara arịa nke obi. Mbenata ịta nke ndị a ihe, na-agwọ ọrịa na-akpa vasodilating edinam.

Ndị kasị dị irè ọgwụ ọjọọ dị otú ahụ na Njirimara bụ "finoptinum". Ntuziaka maka ojiji nke mejupụtara, analogs, na-egosi maka ojiji nke ọgwụ na ya mmetụta na-kọwara dịrị gaba n'ime ebe.

Ụdị, mejupụtara

Gịnị udi bụ ihe e ji mara nke ọgwụ "finoptinum"? Ntuziaka na ngwa na-ekwu na ya nwere ike zụrụ dị ka ntụtụ na mkpụrụ ọgwụ.

Dị ka nọ n'ọrụ mgwa nke a gị n'ụlọnga eme verapamil hydrochloride. Ọzọkwa na nkwadebe gụnyere dị iche iche inyeaka njikọ (dabere na ntọhapụ forms).

pharmacological mmetụta

Olee ihe ndị na pụta ụwa ọgwụ "finoptinum"? Ntuziaka maka ojiji, reviews-ekwu na ọ bụ a calcium ọwa blocker (nhọrọ) mbụ na klas. Ọ bụ a emepụta difenilalkilamina ma kpawa antianginal, antihypertensive na antiarrhythmic edinam.

Antianginal mmetụta nke a ọgwụ na-metụtara ya ike na-emetụta ndị myocardium na elu hemodynamics. Ndị ọzọ okwu, ọgwụ na-ebelata ụda olu nke akwara. Ke adianade do, ọ na-ebelata transformatsiiyu ATP ike nke na-na-ẹdude ke elu-ike mmekọrịta n'ime n'ibu ọrụ ma na-ebelata myocardial contractility.

Anyị ga na-ekwukwa na ihe a ọgwụ budata ebelata myocardial O2 na nwere a na-adịghị mma chronotropic, inotropic na vasodilatory mmetụta.

Njirimara nke ọgwụ

Ruru ya mejupụtara, nke agwọ ọrịa "finoptinum", analogues nke nke na-depụtara n'okpuru ebe a, suppresses ahụ automaticity nke imi ọnụ ebelata AV-conduction na-enwekwu ndị refractory oge.

Ịba ntụrụndụ ugboro diastolic ventricle (n'aka ekpe), a ọgwụ na-ebelata ihe tonus myocardial mgbidi, i.e. bụ inyeaka n'aka maka n'imeso okpo hypertrophic cardiomyopathy.

Ọ kwesịkwara kwuru na-ewere ọgwụ na-egosi na mgbochi arrhythmic Njirimara na supraventricular arrhythmias.

The kinetics nke ọgwụ

Nkwadebe "finoptinum" ntụziaka nke a kọwara n'okpuru ebe a, a na-etinye obi gị dum si digestive tract (ihe dị ka 90% nke dose). Ya mkpakọrịta na a protein bụ 90%.

The ọgwụ na-metabolized na Itie (mbụ) site na imeju. Nke a Nleta ndị dị otú ahụ a emepụta dị ka norverapamil na bụ obere hypotensive ọrụ karịa unmodified verapamil.

The ọkara ndụ oge nke ọgwụ n'elu nnata nke otu usoro onunu ogwu bụ 3-8 awa. Na ojiji nke ugboro ugboro doses nke agwọ ọrịa, nke a ogugu dịgasị (5-12 awa).

Ewepụtara ọgwụ site eriri afọ na akụrụ.

na-agba akaebe

Mgbe ụfọdụ, nye iwu ọgwụ "finoptinum"? Ntuziaka maka ojiji (mbadamba na injectable ngwọta nwere otu oké) na-ekwu na ngwá ọrụ a ga-eji na supraventricular tachycardia (gụnyere paroxysmal, syndrome Lown-Ganong-Levine na WPW-syndrome), ọrịa strok (voltaji, anụ enweghị vasoconstriction, anụ vasospastic), imi tachycardia, atrial flutter, atrial tachyarrhythmia, atrial arrhythmia, hypertensive nsogbu (maka igba ogwu n'akwara ochichi), ọbara mgbali elu, dị oké mkpa ọbara mgbali obere hvs na mgbasa, hypertrophic okpo cardiomyopathy.

contraindications

Mgbe bụghị inye "finoptinum"? Ntuziaka maka ojiji (injections na mbadamba nwere otu contraindications) na-egosi na ngwá ọrụ a na-aju maka ojiji na oké hypotension, sinoatrial nọchibidoro ma na-arịa ọrịa imi syndrome (ma e wezụga na ọrịa na a pacemaker), AV-mgbochi nke atọ na nke abụọ ogo syndrome Launa -Ganonga-Levin na WPW-syndrome na Nchikota na atrial fibrillation ma ọ bụ atrial flutter (ma e wezụga ndị ọrịa na a pacemaker), afọ ime, hypersensitivity ka verapamil, ara.

Drug "finoptinum": ntuziaka maka ojiji

The onunu ogwu nke ọgwụ na gbakọọ dọkịta n'otu n'otu.

Okenye ọrịa mbadamba na-ndinọ ọnụ na mbụ dose of 40-80 mg ugboro atọ n'ụbọchị. N'ihi na onunu ogwu iche-iche na a otu nyere ntọhapụ onunu ogwu ga-amụba, na ugboro nke ochichi - ala.

Kids noo 6-14 afọ, a ọgwụ na-atụ aro iji na-ego nke 80-360 mg kwa ụbọchị, na ruo 6 afọ - na a dose nke 40-60 mg kwa ụbọchị. The ugboro ole nke ochichi nke ọgwụ bụ anọ ugboro n'ụbọchị.

Ọ bụrụ na ọ dị mkpa, ọgwụ na ajụjụ nwere ike ndinọ intravenously (nwayọọ nwayọọ). N'ihi ya, ọ dị mkpa iji nyochaa ECG, ọbara mgbali na obi ọnụego nke onye ọrịa.

Disposable ngwọta onunu ogwu maka okenye ụmụ mmadụ bụ 5,10 mg. Ọ bụrụ na ndị ọgwụgwọ mmetụta anọghị ya, mgbe ahụ, mgbe 20 nkeji nkwadebe nwere ike re-banye (n'otu dose).

A otu onunu ogwu injectable ụdị ọgwụ maka ụmụaka 6-14 afọ bụ 2.5-3.5 mg maka ụmụaka 1-5 afọ - 2-3 mg, na ka nwatakịrị ruo otu afọ - 0.75-2 mg.

Ọrịa na oké imeju kwa ụbọchị dose ekwesịghị gafere 120 mg.

The kacha onunu ogwu nke ọnụ na nkwadebe kwa ụbọchị bụ 480 mg.

mmetụta

Nkwadebe "finoptinum" pụrụ ịkpata ndị na-esonụ n'akụkụ Jeremaya mere:

• ibu ibu, bradycardia, agranulocytosis, ma ọ bụ na-akawanye njọ obi ọdịda, hyperprolactinemia, tachycardia, na-akwụsị akwụsị ọnwụ nke ọhụụ, elu edema;
• Omume Mbelata ọbara mgbali, gynecomastia, galactorrhea, ogbu na nkwonkwo, rịaworo, arrhythmia, akpa ume edema, AV-ngọngọ nke atọ ogo, asystole, thrombocytopenia asymptomatic, ida;
• ọgbụgbọ, isi na ogwe aka ma ọ bụ ụkwụ, gingival hyperplasia, na-ada mbà, ike ọgwụgwụ, na-abawanye na agụụ, nchegbu, na-abawanye na imeju transaminases;
• akpụkpọ ọkụ ọkụ, dizziness, afọ ntachi ma ọ bụ afọ ọsịsa, isi ọwụwa, ịda mbà n'obi, ogwuura, extrapyramidal ọrịa, ike ọgwụgwụ, flushing nke anụ ahụ, na-ehi ụra, exudative erythema multiforme, pruritus.

ọgwụ interactions

Ọ ga-ekwe omume na ikpokọta na ndị ọzọ ọgwụ na nkà mmụta ọgwụ "finoptinum"? Ntuziaka na ngwa na-ekwu na Nchikota ndị a elekọta mmadụ na antihypertensive ọgwụ ọjọọ apụta emesi ha antihypertensive mmetụta.

Site igba ogwu n'akwara ochichi nke verapamil ka ndị na-adịbeghị anya natara a dose of beta-blockers, e nwere a elu n'ihe ize ndụ nke hypotension (ọbara) na asystole.

Mgbe ngalaba-ndinọ "finoptinum" ọgwụ ọjọọ na beta-blockers, ọgwụ maka inhalation anestetiiki na antiarrhythmic ọgwụ ọjọọ na-enwekwu ihe ize ndụ nke na-emepe emepe obi ọdịda, bradycardia, oké hypotension na AV-mgbochi.

Ọnụ na mbanye "Amiodarone" adịkwu bradycardia, ọjọọ inotropic mmetụta, AV-ngọngọ na conduction disturbances.

N'ihi verapamil egbochi isozyme CYP3A4, aka ke metabolism nke simvastatin, lovastatin na atorvastatin nwere ike ụfọdụ na mmekọrịta ngosipụta na-kpatara amụba kasịnụ nke statins ke iyịp. ikpe nke rhabdomyolysis nwere nakwa.

antianginal Njirimara "finoptinum" adịkwu mgbe jikọtara na nitrati.

Ọnụ na mbanye nke acetylsalicylic acid na-ụba na-agba ọbara oge ruru ka mmako antiplatelet edinam.

M ga-"Dizopiramid" ọnụ na ọgwụ ọjọọ, "finoptinum"? Ntuziaka maka ojiji na-akọ na a Nchikota nwere ike ịkpata ajọ hypotension na ida, karịsịa ndị na-decompensated obi bara ma ọ bụ cardiomyopathy.

Mgbe na-eji ma ndị mbadamba na ngwọta enwekwu ya ịta na ọbara na "imipramine", adịru n'ihe ize ndụ nke na-achọghị mgbanwe na ECG. Ọ kwesịkwara kwuru na verapamil enwekwu bioavailability nke "Imipramine", na-ebelata ya nwechapụ.

Na Nchikota ọgwụ ọjọọ na "carbamazepine" enwekwukwa edinam nke ikpeazụ, nakwa dị ka na-enwekwu ihe ize ndụ nke mmetụta si CNS.

N'otu oge na-ewere ọgwụ na "clonidine" e nwere otu obi odida na ndị mmadụ na ọbara mgbali.

Mgbe jikọta agwọ ọrịa na lithium carbonate ngosipụta nke ọgwụ interactions na-ejighị n'aka na weere. E nwere otu nke neurotoxicity, oké bradycardia, welie mmetụta nke lithium na Mbelata ya ịta ke iyịp.

Dị ka "Rifampicin" omume na ọgwụ ọjọọ, "finoptinum"? Manual na-ekwu na a Nchikota induces imeju enzymes, gaa ọsọ ọsọ metabolism nke verapamil. Nke a n'ikpeazụ na-eduga ná a gụnyere ya ná adakarị nrụpụta nke ọgwụ na-atụle.

kpọmkwem na-atụ aro

Ihe i kwesịrị ịma tupu eji ọgwụ "finoptinum" (40 mg)? Guide na-akọ na ngwá ọrụ a na-eji na-ekwesịghị mgbe AV-mgbochi nke mbụ ogo, oké aortic stenosis, bradycardia, myocardial infarction na ọnụnọ nke ekpe ventricular ọdịda, congestive obi ọdịda a-adịghị ala ala uwa, agafeghị oke ma ọ bụ nwayọọ hypotension, hepatic ma ọ bụ gbasara akụrụ insufficiency. Ọzọkwa ọma nke a ọgwụ na-atụ aro ndị agadi na umuaka.

Na nnukwu mkpa na a ga-rụrụ site na a Nchikota ọgwụ nke ọbara mgbali na rịaworo site verapamil na beta-blockers. Ma, ọ dị mkpa izere igba ogwu n'akwara ochichi nke ikpeazụ.

N'elu n'ikuku nke a pụtara onye ọrịa nwere ike ịzụlite dị otú ahụ Jeremaya mere dị ka iro ụra ma ọ bụ dizziness, nke nwere ike imetụta mmadụ ike ịrụ ize ndụ-arụ ọrụ.

Pregnancy na lactation

Ma ọ bụ na o kwere omume ga-eme n'ọdịnihu ọhụrụ nne kenyere ọgwụ "finoptinum"? Ntuziaka maka ojiji n'oge ime nwere ya na nke a pụtara mmetụta dị njọ n'ahụ nwa ebu n'afọ na mmepe. Ọ na-aga n'ime mmiri ara. Ya mere, n'okpuru ọnọdụ ndị a ọgwụ na-nditịm contraindicated.

Agwọ ọrịa "finoptinum": ogbo na-eri

The price nke ngwá ọrụ a nwere ike dị iche iche. Dị ka a na-achị, ọ na-adabere n'ụdị ntọhapụ nke ọgwụ, ya buru ibu ma ọ bụ akporo. The nkezi na-eri "finoptinum" bụ 100-170 rubles.

Ọ bụrụ na-ewere a ọgwụ ị na-contraindicated, ọ nwere ike dochie anya otu n'ime ndị na-esonụ n'aka: "Verapamil", "Verogalid" "Verapamil-OBL", "Kaveri", "Verapamil Sopharma", "Verapamil-Lect," "Verapamil-Verein" "verapamil-ratiopharm" "Isoptin", "verapamil-Escom," "Vero verapamil," "verapamil hydrochloride" "Lekoptin".

Nyocha nke dọkịta na-eji ọkụ

Ọkachamara na-ekwu na mbadamba na ngwọta "finoptinum" bụ irè na ọnụ ụzọ, bụ ndị e mere iji weghachi ọbara mgbali, ma melite ọma a na ọrịa ndị ọzọ obi na ọbara arịa.

Dị ka ndị ọrịa, ọtụtụ n'ime ha bụ nnọọ afọ ojuju na-arụpụta nke ọgwụgwọ na a n'ụlọnga. Mkpụrụ ọgwụ ma ọ bụ igba ogwu n'akwara infusion ngwọta mmemmem ngwa mkpochapu mgbaàmà nke ọbara mgbali na ndị ọzọ na ihe ịrịba ama nke ọrịa nke obi usoro.

Anyị ga na-ekwukwa na banyere ọgwụ na hụrụ na-adịghị mma na-akọ. Ha na-ekwu nke a ọnụ ọgụgụ buru ibu nke n'akụkụ Jeremaya mere na-erukwa na ozugbo iji ọgwụ. Ọzọkwa, ọtụtụ ọrụ mkpesa banyere ọtụtụ contraindications.