Gịnị bụ Addison ọrịa?

Addison ọrịa na-adị mgbe ndị malfunction nke adrenal cortex. Ọrịa a na-chọpụtara na ma ndị ikom ma ndị inyom, na-akasị katatụrụ (30 40 afọ). Ọ bụ obere ọrịa, nke na-aha na otu onye kwa 100 puku. Population. Addison Biermer ọrịa nwere ike ịzụlite n'ihi autoimmune Filiks, na-efe efe (syphilis, ụkwara nta na ọrịa ịba adrenals), na na amyloidosis na ịza aza etuto ahụ. Na 70% nke ọrịa, ọrịa emee ka a n'ihi nke ọdịda ke dịghịzi usoro (-alụso ọrịa ọgụ na-amalite na-mkpụrụ ndụ maka mba ozu, awakpo na-ebibi ha). Na mbibi nke adrenal cortex mkpụrụ ndụ mbelata njikọ gluco na mineralocorticoids (cortisol, 11-deoxycorticosterone, aldosterone). Ọkà mmụta sayensị egosiwo na glucocorticoids mezie iche iche Biochemical Filiks na ahu (achịkwakwa ọbara mgbali, insulin ịta, na-agụnye ụkpụrụ nke protein njikọ, lipids na carbohydrates).

Gipokortitsizm mgbe hụrụ ọrịa emeso ya na homonụ nke adrenal cortex. N'ọnọdụ ka ukwuu, na etiology nke ọrịa ka na-anọgide na-amaghị ama. Adrenal insufficiency nkewa bụ isi na sekọndrị. Primary ọdịda amalite na mmeri nke adrenal anụ ahụ, na nke abụọ - ruru ka ezughi oke mmetuta nke adrenocorticotropic hormone.

Addison si Disease Mgbaàmà

Clinical ihe ịrịba ama nke ọrịa mere site erughi na organism ịnweta ma glucocorticoids. The kasị mara ndị na-adịghị ike, hypotension, dysfunctional eriri afọ (ọgbụgbọ, ọnwụ nke agụụ, vomiting, afọ ntachi, afọ ọsịsa bụ nke na-anọchi). Ụfọdụ ọrịa hypochlorhydria.

Addison ọrịa na-esonyere ụba ogwe ma ọ bụ ndị dara mbà n'obi na ọnọdụ, Ugboro isi ọwụwa na ehighị ụra nke ọma. X-ray nke obi na-egosi na a ọnụ ke obi size. The ngwá detụrụ ihe ịrịba ama nke hyperkalemia (elu potassium ịta n'ime ọbara). Skin pigmentation adịghị na-egosipụta ịdị njọ nke ọrịa, Otú ọ dị, na-abawanye ma ọ bụ ibelata ya na ọgwụgwọ nke na-egosi na irè nke ọgwụgwọ ihe.

Addison ọrịa e ji mbido nke abụọ mgbaàmà obere oké. Nnọọ adịkarịghị ọrịa na-egosipụta onwe enweghị pigmentation (ka aha "ọcha Addison"). Isi kpatara nke a na ọrịa bụ ụkwara nta adrenals. Na enweghị ọgwụgwọ kwesịrị ekwesị Addison ọrịa mgbagwoju anya. Clinical ihe ịrịba ama na-adịkwu: ọgbụgbọ, vomiting, afọ ọsịsa, ọbara mgbali tụlee sharply, na-amụba ịta nke potassium ke iyịp. Na elu ọbara nke mmapụta nitrogen enwekwu ọnụ ọgụgụ nke mkpụrụ ndụ ọbara uhie, haemoglobin. Ya mere, ọ bụrụ na oge nke nsogbu addisonicheskogo ọrịa anaghị enye adọ aka, na ọ nwụrụ anwụ na ihe ịrịba ama nke gbasara akụrụ na ọrịa obi.

Ihe kacha mkpa ime nnyocha parameters maka nchoputa bụ ọdịnaya nke 17 na-OCS na plasma na 17-KS na mmamịrị, nakwa dị ka a ọnụ ke ọbara glucose etoju. Morphological nnyocha nke ọbara na-egosi lymphocytosis, eosinophilia na ESR egbu oge.

Addison ọrịa na-ọdịiche dị n'etiti ndị na-esonụ ọrịa: ọla-arịa ọrịa shuga, pellagra, nsi arsenite na Bismut Argentum. The ọrịa na nwere a-adịghị ala ala N'ezie na oge peaking. Addison Biermer ọrịa ogo kpebisiri ike site ogo nke isi ihe ịrịba ama nke ọrịa, nakwa dị ka site na ọnụ ọgụgụ nke ọgwụ ndị na-mkpa iji chefuo adrenal insufficiency.