"Kalchek": ntuziaka maka ojiji, analogs, reviews

Ihe i kwesịrị ịma tupu eji a ọgwụ, dị ka "Kalchek"? Ntuziaka maka ojiji nke si ọgwụ ọjọọ chọrọ ịgụ. Na ya na ị ga-ahụ na-egosi na contraindications maka ojiji nke a ọgwụ, nakwa dị ka ịchọpụta ma ọ bụrụ na ha nwere ihe ọ bụla analogues na mmetụta.

N'ụdị nkwadebe, mejupụtara na mbukota

Ị maara na ụdị nke ị nwere ike ịzụta ọgwụ "Kalchek"? Ntuziaka maka ojiji na-agwa anyị na ọgwụ dị naanị na mbadamba ụdị. The mejupụtara nke agwọ ọrịa na-agụnye nọ n'ọrụ mgwa dị ka amlodipine besylate (5, 2,5 na 10 mg). N'ihe gbasara ndị ọzọ bekee, mgbe ha na-agụnye dibasic calcium phosphate, ọka starch, sodium starch glycolate, ọcha talc, colloidal silica na magnesium stearate.

The mbadamba na-ọnya (10 PC.), Nke na-enịm ke a igbe mere nke kaadiboodu.

The pharmacological Njirimara nke a na ngwaọrụ ụlọọgwụ

Olee otú ọgwụ "Kalchek"? Ntuziaka maka Iji na-ekwu na ọgwụ bụ a nhọrọ calcium ọwa blocker nke 2nd klas. O nwere antianginal, antihypertensive, vasodilating, na antispasmodic mmetụta. Medicinal ihe gụnyere ke mejupụtara nke a nhọrọ, nwee ike nke igbochi eruba nke calcium ion n'ime vaskụla ezigbo muscle mkpụrụ ndụ.

Anti-hypertensive Njirimara nke ọgwụ ruru ya kpọmkwem izuike mmetụta vaskụla ezigbo muscle. Banyere mgbochi anginal mmetụta, na agwọ ọrịa na ajụjụ bụ ike mụbaa arterioles (elu). Mgbe e mesịrị, a na-eduga ná a ọnụ ke elu vaskụla eguzogide, nke n'aka nke na-eduga ná a ọnụ ke myocardial ina O ₂ (oxygen).

Otú ọ dị, ọ ga-kwuru na mgbe ụfọdụ ihe nke a pụtara na ọkọnọ nke oxygen, on Kama nke ahụ, mụbara. Nke a bụ n'ihi mmụba nke akwara akwara (e.g., vasospastic rịaworo).

Ọ ga-kwuru na mbadamba "Kalchek" ọ dịghị oghom mmetụta na lipid mejupụtara ọbara. Ha nwere antithrombotic na antiatherosclerotic ọrụ, dịkwuo filtration ọnụego (glomerular), na na-enwe na a bland natriuretic mmetụta.

Na-arịa ọrịa shuga nephropathy ọgwụ adịghị ike nke na-amụba microalbuminuria.

The pharmacokinetic Njirimara nke ọgwụ

Ebe absorption nke ọgwụ "Kalchek"? Ọbịa ọkachamara na-atụ aro na absorption nke ọgwụ na-ewepụtara digestive tract (banyere 90%). Ya kasị ukwuu ịta n'ime ọbara mgbe 7-12 awa. The bioavailability nke ọgwụ bụ banyere 63-65%.

N'ọrụ ọgwụ umi penetrates ọbara-ụbụrụ mgbochi a na ọ na-anyụpụ na mmiri ara. Amlodipine biotransformed na imeju (adịghị ejekwa metabolites ii).

Na-agbanweghi agbanwe mmepụta nke na-erughị 10% nke Nwa. Banyere na-adịghị ejekwa metabolites, ha na-egosipụta na ihe ego nke 60% na mmamịrị, na banyere 20-25% site na nsia na ọnụ na bile.

egosi

Na ihe ọrịa a ndidi mkpụrụ ọgwụ "Kalchek" nwere ike na-kenyere? Ntuziaka maka ojiji (yiri ngwá ọrụ e gosiri n'okpuru)-enye ihe ọmụma ndị na-esonụ na-egosi:

• mụ rịaworo;
• ejighị n'aka rịaworo;
• Ọbara mgbali elu (eji dị ka a monotherapy ma ọ bụ na Nchikota ọgwụ na Ace inhibitors, thiazide diuretics, beta ma ọ bụ Alfa blockers);
• rịaworo angiospastic (ma ọ bụ na-akpọ Prinzmetal rịaworo).

contraindications

Na ọnụnọ nke ọ bụla ọnọdụ onye ọrịa na-ekwesịghị kenyere mkpụrụ ọgwụ "Kalchek"? Ntuziaka maka ojiji e dere ihe na-esonụ contraindications:

• ọbara hypotension;
• Hypersensitivity isi nọ n'ọrụ umi ọgwụ.

Ọ kwesịkwara kwuru na ọgwụ ike ga-eji nke ndị ọrịa nwere a hypersensitivity ka dihydropyridine emepụta.

Drug "Kalchek": ntuziaka maka ojiji

Mbadamba "Kalchek" rịaworo na ọbara mgbali na-ndinọ na a onunu ogwu nke 5 mg kwa ụbọchị. Ọ bụrụ na ọ dị mkpa, nwere ike mụbara ka 10 mg.

Ọrịa na chọpụtara dị ka dilated cardiomyopathy, ọgwụgwọ na-butere na Dosages nke 2.5 mg kwa ụbọchị. Ọ bụrụ na ọgwụ a na-dịtụ ọma anabata, ọ bụ omume na-eji nwayọọ nwayọọ dịkwuo dose (adịghị nnọọ 10 mg kwa ụbọchị ahụ).

Na ngwa nke mbadamba dị ka akụkụ nke Nchikota ọgwụ na beta-blockers, thiazide diuretics ma ọ bụ Ace inhibitors ukpụhọde nke dosing Usoro a chọrọ.

Ịrịba ama nke ovadozu na ọgwụgwọ usoro

Gịnị bụ ihe ịrịba ama nke ovadozu-eme mgbe ndị na-ezighị ezi dose ọgwụ "Kalchek"? Analogues na ọgwụ onwe ya nwere ike ime ka akpọ hypotension. Dị ka ọgwụgwọ ọrịa e kwesịrị a kehoraizin ọnọdụ, na ubé ebuli ya ụkwụ. Ke adianade do, ọ dị mkpa ka na-akwado ndị na-arụ ọrụ nke obi na ọbara arịa, nlekota egosi nke akpa ume ọrụ nke usoro, akara nke diuresis na Bcc.

Iji weghachi vaskụla ụda ndidi e nyere a vasoconstrictor ọgwụ ọjọọ. Iji kpochapụ mmetụta nke calcium ọwa mgbochi ahụ, onye ọrịa na-ndinọ (i.v.) calcium gluconate.

ọgwụ interactions

N'otu oge mkpụrụ ọgwụ "Kalchek" na "Warfarin" ọgwụ adịghị ime ka ịrịba mgbanwe prothrombin oge na ike na-anọchite anya nke ike inwe mmekọahụ.

Mgbe ị na-eji ma na-atụle agwọ ọrịa na ọgwụ "Digoxin" Enweela dịghị mgbanwe ọbara ịta nke ikpeazụ, na ya gbasara akụrụ nwechapụ.

N'otu oge ochichi nke ọgwụ ọjọọ "Kalchek" na "Cimetidine" enweghị mmetụta na pharmacokinetic Njirimara nke amlodipine.

Pregnancy na lactation

Ma ọ bụ na o kwere omume n'oge lactation na gestation omume n'ikuku "Kalchek" mbadamba? Ntuziaka maka ojiji, ezigbo dọkịta agwa na nrụpụta na nchekwa nke a ọgwụ n'oge ime na ara-udia nwa gị na-agaghị.

Mmetụta nke ọgwụ

Gịnị mmetụta nwere ike ime ka mkpụrụ ọgwụ "Kalchek"? Ntuziaka maka eji ngwá ọrụ a na-akwado eziokwu ahụ bụ na ya oru nwere ike ime ka na-achọghị Jeremaya mere ke idem. emekarị bụ ndị ha na-na-esonụ:

• Arịa na obi, mkpụmkpụ nke ume, palpitations, na-ekpo ọkụ flushes.
• The ụjọ usoro (elu na etiti): ọnọdụ mgbanwe, dizziness, muscle cramps, isi ọwụwa, bịara ikiri ọhụụ, iro ụra, asthenia, ike ọgwụgwụ, paresthesia na myalgia.
• Digestive tract: abdominal mgbu, dyspepsia, cholestatic jaundice, ọgbụgbọ, na-abawanye na transaminases (imeju).
• Skin: erythema multiforme, pruritus, ihe ọkụ ọkụ.
• Ndị ọzọ: gingival hyperplasia, gynecomastia, mụbara ugboro ole nke urination, enweghi ike na ọzịza.

Special ntuziaka maka inweta ọgwụ

Olee ụdị nuances atụle ọgwụ kwesịrị ịma tupu ị na-ebu on ewere mbadamba "Kalchek"? Ọbịa ọkachamara na-ekwu na nke a ọgwụ ga-eji na oké ịkpachara anya ka ndị mmadụ na mkpọchị imeju ọrụ, nakwa dị ka obi ọdịda (adịghị ala ala) na aortic stenosis.

Imekotaotuugbo n'ikuku nke ọgwụ "Kalchek" na-abụghị steroidal mmadụ, nitrates, ọgwụ nje na hypoglycemic ọgwụ (onu) bụ omume.

Ahụmahụ nke na-adakarị ojiji nke ọgwụ na-eto eto ụmụ na-efu efu.

Mbadamba "Kalchek" enweghị mmetụta na onye ọrịa nwere ikike iji ụgbọala a ụgbọ ala.

Usoro na ọnọdụ nke nchekwa nke ọgwụ

Nkwadebe "Kalchek" (5, 10 na 2,5 mg) ga-echekwara na a jụụ, akọrọ, ọchịchịrị ebe nke iru nke obere ụmụaka. Adị ndụ nke na mbadamba bụ 2 afọ.

Nyocha nke ọgwụ ngwaahịa, na-eri nke ya analogues

Gịnị nwere ike dochie a ngwá ọrụ ndị dị ka "Kalchek"? Analogs nke a ọgwụ ndị dị na fọrọ nke nta niile drugstores. Otu n'ime ihe ndị kasị nkịtị mmadụ na-agụnye ndị na-esonụ ka ọgwụgwọ: "Agen", "Tenoks" "adipic", "Stamlo", "Akridipin", "Omelar Cardio", "Amlo", "normodipin" "Amlodipine" "Norvasc" "Amlovas", "Amlorus", "Norvadin", "Amlodigamma", "Cordy Cor", "Amlodhi", "Korvadil", "Amlodifarm", "Karmagip", "Amlokard-Sanovel", "cardilopin", "Amlong" "Vero Amlodipine", "Amlotop", "Amlonorm".

Gịnị bụ ndị na-eri ego? The nkezi price nke ọgwụ bụ 175-190 Russian rubles (5 mg, 30 mbadamba).

Banyere kwuru nke ọrịa, ha na-mma n'ihi na ọtụtụ akụkụ. Dị ka ndị na-ebi etinyere na nkà mmụta ọgwụ, ọ dị irè ọgụ na rịaworo na ọbara mgbali. Ọ kwesịkwara kwuru na a ọnụ ọgụgụ buru ibu nke ndị ọrịa obi ụtọ na eziokwu na nke a ọgwụ ọjọọ na-dịtụ ọma anabata ha. Ọ bụ ezie na ụfọdụ ndị Erere "Kalchek" ka eme ka mmetụta ndị dị otú ahụ dị ka isi ọwụwa, abdominal mgbu, dizziness, ọgbụgbọ na nfụkasị Jeremaya na akpụkpọ.