Medicine "primidone": ntuziaka maka ojiji na nzaghachi

Modern ọgwụ na ụlọ ọrụ ndị na-emepụta a ọnụ ọgụgụ buru ibu nke antiepileptic ọgwụ ọjọọ. Olee otú ịghọta dịgasị iche iche nke ọgwụ ọjọọ eme ihe? Iji mee nke a, na-echigharịkwuru ahụmahụ ọkachamara. Ọ ga-enwe ike ịhọrọ ihe ị kasị dị irè na nkà mmụta ọgwụ, nke ga-eme ka ịrịba onyinye nke onye ọrịa.

The kasị ewu ewu na antiepileptic ọgwụ n'etiti ọrịa na dọkịta bụ ọgwụ "primidone". Ntuziaka maka ojiji nke si ọgwụ ọjọọ, ntọhapụ ụdị na ya Njirimara ga-ọkọnọ a obere ka e mesịrị.

The mejupụtara, na udi ma na nkwakọ

Ịzụta ọgwụ "primidone" nwere ike ịbụ na abụọ dị iche iche iche-iche. Ọ bụ dị ka a ntụ ntụ na a na-packaged ke a sọrọ-oyi akwa plastic akpa na kaadiboodu igbe, karị. Ọ pụtakwara na ị pụrụ ịzụta n'ụdị mbadamba ọnya Ukwu na katọn.

N'ọrụ mgwa a ọgwụ eme primidone. Ọzọkwa ya mejupụtara auxiliaries (dabere na ntọhapụ forms).

The edinam nke ọgwụ

Gịnị bụ ọgwụgwọ maka "primidone"? Ntuziaka maka ojiji na-egosi na nke a antiepileptic ọgwụ. Ọ na-eme ka nwayọọ hypnotic mmetụta, ma ebelata excitability nke akwara ozi na-emi odude ke akwụkwụ na-elekwasị anya.

Olee ihe ndị ọzọ Njirimara pụta ụwa na agwọ ọrịa "primidone"? Mkpa tremor mgbe ọ na-eliminates ọbara ịta nke 12 .mu.g / ml.

kinetic Njirimara

Drug "primidone" (mbadamba na ntụ ntụ) pụtara ngwa ngwa ma ọ fọrọ nke nta n'ụzọ zuru ezu etinye obi gị dum na eriri afọ tract. The kasị elu ịta nke ọgwụ enweta mgbe awa atọ. The bioavailability nke a ọgwụ bụ 90-100%. N'ime ọbara ya ejikọ na-edozi ubé (ihe dị ka 20%).

Ọkara ndụ-nke a na gị n'ụlọnga bụ 7-15 awa.

Na imeju, na agwọ ọrịa bụ ikpe converted ka phenobarbital (banyere 20%) na feniletilmalonamid. Ndị a metabolites nwere antiepileptic ọrụ. Ha anyụpụ site na akụrụ ya.

The ọrịa ọbara dị mkpa ịnọgide na-enwe a na ọgwụgwọ ọgwụ ịta nke 12 ug / ml. Ọ bụ ndị a na-egosi na-eme ka slowing ọdịdọ. Mgbe ụdị ndị ọzọ nke Akwụkwụ na-adọ (e.g., na-abụghị convulsive forms of polymorphous ọdịdọ na ndị ọzọ), mmetụta nke ọgwụ na-bụghị mgbe niile na-enweta. Na nke a, mgbagwoju ọgwụgwọ.

Egosi maka ojiji nke ọgwụ

Mgbe ụfọdụ, ọrịa na-kenyere ọgwụ ndị dị otú ahụ dị ka "primidone"? Nyocha kọrọ na ngwá ọrụ a n'ụzọ dị irè na-emeso Akwụkwụ na-adọ nke dị iche iche si malite, nakwa dị ka ele mmadụ anya n'ihu na generalized ọdịdọ. Na mmepe nke Baịbụl hiwere isi n'ebe, myoclonic na akinetic ọdịdọ a na nkà mmụta ọgwụ na-erughị irè.

Contraindications ọgwụ

Mgbe ụfọdụ, adịghị idepụta ọgwụ "primidone"? Ntuziaka maka ojiji nke na-akọ na a machibidoro iwu iji n'aka na ọnụnọ nke a hypersensitivity (gụnyere barbiturates), nakwa dị ka anaemia, imeju na-na akụrụ odida, afọ ime, radieshon na ara.

Medicine "primidone": ntuziaka maka ojiji

Na ihe onunu ogwu na-kenyere a ọgwụ anyị na-atụle? Ọ na-e jikwa ọnụ mgbe nri oriri na a otu otu oge dose of 125 mg. Mgbe ahụ, ọ bụla ụbọchị atọ, kwuru na ọtụtụ ọgwụ mụbara site 250 mg maka okenye ọrịa na 125 mg maka ụmụaka ndị ruru afọ 9.

Nke a ọgwụ na-aga n'ihu ruo mgbe mkpuruedemede N'ihi.

The kacha kwa ụbọchị dose maka ụmụaka 1 g (ná nkebi abụọ) na ndị okenye - 1.5 g

mmetụta

Dị mwute ikwu na, tupu anyị antiepileptic ọgwụ na-akpatakarị ekwesighi mmetụta. A na-agụnye oké ụra, isi ọwụwa, dizziness, nchegbu, lethargy, ọgbụgbọ, anaemia, vomiting, leukopenia, nfụkasị Jeremaya, na lymphocytosis.

Nnọọ adịkarịghị ifịk agwọ ọrịa nwere ike ime ka nystagmus, ataxia, "lupus" syndrome, psychotic Jeremaya mere, arthralgia, megaloblastic anaemia, na ruo ogologo oge iji - ọgwụ na nduzi.

ikpe nke ovadozu

Inweta nnukwu doses nke ọgwụ nwere ike ime ka mgbaàmà ndị dị otú ahụ dị ka dizziness, ataxia, ọgbụgbọ, na ịda mbà n'obi nke Central ụjọ usoro ọrụ. Maka ọgwụgwọ nke ọnọdụ ndị dị otú ọrịa na-asa afo, rụọ ọrụ unyi na symptomatic ọgwụgwọ.

Ndakọrịta na ndị ọzọ ọgwụ ọjọọ eme ihe

Nkwadebe "primidone" emepụta potentiates mmetụta nke cyclophosphamide, methotrexate na sulfonylureas nakwa dị ka hypnotics. Ọ na-accelerates metabolism, enwekwu ọrụ nke microsomal imeju enzymes, ebelata mmetụta nke corticosteroids, acetaminophen, ISS, tricyclic antidepressants, anticoagulants, "Chloramphenicol", "DTIC", "Cyclosporin" gbasara obi glycosides "disopyramide", "Levothyroxine", "Doxycycline "" theophylline "," metronidazole "," Quinidine "," mexiletine "nke vitamin D,« fenoprofen, "caffeine" Aminophylline "na" oxtriphylline. "

E lee ya anya agwọ ọrịa enhances CNS ịda mbà n'obi na Nchikota na-esi a Central depremiruyuschim edinam na-aba n'anya.

Drug "amphetamine" slows ala absorption nke phenobarbital.

Nchikota na carbonic anhydrase inhibitors adịkwu osteopenia.

Nke a na-ebelata ihe absorption nke griseofulvin gị n'ụlọnga na-ebelata ya antifungal ọrụ. Ọ na-enhances nsí mmetụta "enflurane", "methoxyflurane" na "halothane".

"Methylphenidate" akwalite mgbochi nke metabolism na primidone ntọt ya ịta ke iyịp.

"Leucovorin" nnukwu doses ebelata mmetụta nke anticonvulsant primidone. The otu na-emetụta ọgwụ "phenylbutazone".

kpọmkwem na-atụ aro

Drug "primidone" nwere ike ga-eji na mgbagwoju anticonvulsant ọgwụgwọ. Kagbuo na nnọchi nke ọgwụ bụ nwayọọ nwayọọ.

Na oke-elekọta, a họpụtara ya na ndị agadi na immunocompromised ndị mmadụ. Na mmepe nke megaloblastic anaemia agwọ ọrịa kagbuo na idepụta ọgwụgwọ na vitamin B12 ma ọ bụ folic acid.

Isiokwu gị n'ụlọnga na-ebelata mmadụ psychomotor Jeremaya mere. Ya mere, ọ na-adịghị nye iwu ndị ọkwọ ụgbọala nke ugbo ala na ndị na-arụ ọrụ e jikọtara ya na ize ndụ ígwè.

Na-elekọta a ọgwụ na-eji na ụmụ.

yiri n'aka

The ọgwụ nwere ike dochie anya "primidone"? Analogues nke ngwá ọrụ a nwere ike zụrụ n'oge ọ bụla ahịa ọgwụ ma ọ bụ iji site na World Wide Web.

Dị ka ọkachamara, nwere yiri Njirimara ndị dị otú ọgwụ dị ka "hexamidine", "Benzonal" na "Phenobarbital".

nleba

Bụghịkwa ndị na-ewere antiepileptic ọgwụ ndị dị otú ahụ dị ka "primidone" ahapụ ya naanị mma nzaghachi. Dị ka ha na-akọ, ọgwụ si anagide ọma na ya ọrụ. Ọ na-egbochi omume nke ele mmadụ anya n'ihu na generalized ọdịdọ. Ọzọkwa, a na nkà mmụta ọgwụ na-enyere aka belata ihe mgbaàmà nke Akwụkwụ na-adọ.

Ma ihe ndị na-ezighị ezi reviews, fọrọ nke nta niile ha na-ezo aka n'eziokwu ahụ bụ na ngwá ọrụ a na-eme ka ntoputa nke a ukwuu nke mmetụta. Ya mere, itinye dị otú ahụ a usọbọ kwesịrị ịbụ naanị n'ihi na ndị dọkịta na oru.