Nditre - ihe bụ nke a? atụmatụ

Ọ dịwo chere na afo na gburugburu ebe obibi, dịtụ akpali mmasị ebe obibi ya microflora. Na afo, na ya esịtidem content - acid, ma ọ bụ nanị na-adị ndụ a otu organism. Nchọpụta nke Helicobacter pylori na eriri afọ tract gbanweworo echiche nke ọdịdị nke eriri afọ ọrịa: mgbu, duodenitis, gastric ọnyá afọ na duodenal ọnyá, eriri afọ cancer na ọgwụgwọ ha. N'isiokwu a anyị na-atụle n'ụzọ zuru ezu ihe nditre. Ọ bụ a kpọmkwem usoro ọgwụgwọ na aghọwo nnọọ ewu ewu na-adịbeghị anya.

Njem mmụta n'ime akụkọ ihe mere eme nke Helicobacter pylori

N'ezie, na nje bacteria chọpụtara a ogologo oge na ọ bụghị otu ugboro. N'ihi na oge mbụ a mere na njedebe nke ikpeazụ nke narị afọ. Ọ bụ 1886. Jagiellonian University Prọfesọ V. Yavorsky ịchọpụta bacteria e ji mara gburugburu udi gastric ihe onwunwe. O nyere aha nke nje bacteria Vibrio rugula, na-atụ aro na ọ na-arụ ọrụ na mmepe nke gastric ọrịa.

Otú ọ dị, n'ihi na anya bụghị Yavorsky ọrụ na ahụ ike na obodo. Mgbe afọ asaa gasịrị, na Italian ọkà mmụta sayensị D. Bidzodzero sere dị microorganisms si digestive tract nke nkịta. The ọzọ, bụ ndị e kwuru na ọnụnọ nke nje bacteria na afo mkpụrụ ndụ si ejikwara ọnyá ọrịa bụ Prọfesọ Morozov Moscow. Na ọ bụ na ọgwụgwụ nke 70s nke ikpeazụ nke narị afọ.

Ọzọkwa mgbalị n'ụzọ ụfọdụ na-akọwa, were, na-eto eto na laabu na-enyocha amaghị na nje bacteria na e na-eme na 1979 na 1981 Australia Marshall na Warren. Na ha ịga nke ọma. Marshall ẹkenịmde ọma ahụmahụ nke onwe onye na-oria nke Helicobacter pylori na-agwọ ọrịa nke helicobacter mgbu enwetara site na a izu abụọ ọgwụgwọ na "metronidazole" na bismuth salts.

Nke a na usoro Nleta ndabere nke oge a na nditre Helicobacter pylori. A obi ike nchọpụta na 2005 natara Nobel chọr'inwe na Medicine.

Aha Helicobacter pylori organism bụ na 1989, nakwa dị ka a zuru ezu nkọwa na nhazi ọkwa. Gburugburu na nje bacteria ebe obibi họọrọ "nche ọnụ" nke afo ( "pylori" - si Greek "nche ọnụ") infects niile ebe nke duodenum na afo. Na a ịrịba pasent nke niile mgbu, duodenitis, nsia ọnyá afọ na duodenal ọnyá ruo mgbe ha cancer bụ ikpe mara nke a microorganism.

Ihe ize ndụ nke ibute ọrịa na Helicobacter pylori?

Helicobacter pylori, bi na eriri afọ tract nke mmadụ ma ọ bụ anụmanụ na pores na-akpa àgwà dị. Na nwetụrụ ọdịda ke dịghịzi usoro ma ọ bụ site na cumulative mmetụta nke erighị ma ọ bụ adịghị mma àgwà ọrụ na nje bacteria na-aghọ ike ike. Gịnị ka ọ bụ dị ize ndụ? Ibi na mucous akpụkpọ ahụ nke esịtidem akụkụ - afo na duodenum - pathogenic microorganism-eme omume ya.

Starts ụba ntọhapụ nke nzuzo, nke dị njọ na-emetụta ndị eriri afọ anụ ahụ. Mucous ha na-rụrụ, agbajikwa, e nwere ihe dị ukwuu nanị ire ọkụ ebe e guzobere onya. Adịghị ala ala mgbu mere site pathogenic microorganism Helicobacter pylori otu, n'adịghị ot n'ibu mgbu, na-adịghị amenable iji gwọọ site ot ụzọ.

Helicobacter pylori penetrates niile miri n'ígwé nke anụ ahụ, si otú unaffected ọtụtụ ọgwụ nje (ọgwụ nje na-ejighị n'aka na acidity). Dị otú ahụ vandalnye omume ya ime ka irreversible Filiks ke mucosa, n'ihi na ihe atụ, a precancerous ọnọdụ, na, ozugbo, mmepe nke oncology. Iji zere nke a, tinye nditre Helicobacter.

Diagnosis nke Helicobacter pylori na eriri afọ tract

Ọ bụrụ na onye ọrịa ọdọhọde nke ọgbụgbọ na afọ mgbu, nrekasi obi, ihe mgbu, na nsogbu na-a oche, a na-egbu mgbu erughị ala na epigastric region - a kpọmkwem na-egosi na-anwale n'ihi na ọnụnọ nke organism Helicobacter pylori. Eneme mgbazinye bụ:

• ọbara, n'ozuzu analysis nke antibody, gụnyere ọnụnọ nke H. pylori;
• stool analysis n'ihi na ọnụnọ nke bacteria n'efu;
• ume ule dabeere mkpebi siri ike nke amonia ịta na ume e kupụrụ ekupụ;
• cytologic analysis.

Ndị kasị pụrụ ịdabere na usoro nke Ịchọpụta Otú Nsogbu ọrịa bụ a anụ ahụ biopsy nke gastric mucosa na duodenal ọnyá afọ. The ákwà na-weere analysis site endoscopy.

egosi nditre

Ka ugbua kwuru n'elu, na nditre - bụ a ụzọ obibi gastric akpata.

Nditre rụrụ na-arịa ọrịa ndị dị otú ahụ pathologies:

• ọnyá mgbaàmà na afo na duodenum;
• ọnọdụ post resection (ịwa ahụ iji wepụ cancer);
• precancerous ekwu na ozu anụ ahụ atrophy;
• lymphoma.

Na n'ihe ize ndụ bụ ndị ikwu ahụhụ ọrịa cancer. Na-atụ aro nditre ọgwụ na na ọrịa na gastroesophageal reflux ọrịa na ọtọ dyspepsia.

nditre ụzọ

Nditre - bụ mbibi, nditre (English nditre.). Nke a na ezu, e mere ibibi ọrịa na Helicobacter pylori eriri afọ tract. The usoro ọgwụgwọ na-owụt ke ọrịa na oké gastric ọnyá afọ ma ọ bụ duodenal ọnyá afọ. Ya kachasi mkpa idu ke N'ezie oriri nke ọgwụ na a kpọmkwem ụkpụrụ.

Tupu mmalite nke N'ezie na-mụụrụ n'ihu ọmụmụ gastric mucosal anụ ahụ n'ihi na ọnụnọ nke ịza mkpụrụ ndụ.

Helicobacter pylori nditre nwere ọtụtụ ụdị:

• mono, ebe ọdabara na ọgwụgwọ nke naanị otu na-anata n'aka, na-emekarị ka ọgwụgwọ dabeere na bismuth salts, ma ọ bụ ọgwụ nje;
• Duo, sọrọ ọgwụ (vismutosoderzhaschee umi plus ọgwụ nje);
• triplet, dị ka aha-apụta, a ọgwụgwọ na atọ ọgwụ ọjọọ (bismuth, ọgwụ nje na a nnọchiteanya imidazole otu);
• kvadriplet, na-etolite a anọ, nke a mgbagwoju triplet kwukwara mba ọgwụ (blockers nke hydrochloric acid).

Mono-nditre - a na-fọrọ nke nta mgbe eji ọgwụgwọ usoro n'ihi na nke adịghị irè (n'okpuru 50%). Ọ nọ na-ewu ewu na chi ọbụbọ nke oghere na mbụ nwere helikobakterialnoy emeso ọrịa.

Nditre iji abụọ ọgwụ nwere arụmọrụ nke mkpofu helicobacter banyere 60%, na kwa nta taa eme eme. Gịnị bụ na-eji taa nditre? Ọgwụgwọ regimens na-eji.

Tripletoterapiya agụnye a bismuth compound, ọgwụ nje (amoxicillin na-esiwanye eji klaritomitsin) na imidazoles (a ọgwụ).

N'ezie nke anọ ọgwụ - niile dị n'elu formulations plus proton mgbapụta inhibitors (otu a antiulcer ọgwụ iji na mbenata gastric acid mmepụta). Ụzọ ya arụmọrụ bụ arụmọrụ indices 90% na 95% karị. Lee ụfọdụ irè nditre Helicobacter pụrụ.

Ọgwụ na-eji maka nditre

N'ihi na acidic na gburugburu ebe obibi nullifies mmetụta nke ọtụtụ ọgwụ nje, a ndepụta ọgwụ ikpochapụ nnọọ obere:

• ọgwụ nje;
• antiinfectives;
• vismutosoderzhaschie ọgwụ ọjọọ;
• proton mgbapụta inhibitors;
• probiotics na prebiotics.

Ọgwụ nje na-akacha eji na nditre ọgwụ

Olee na-amalite nditre? Ọgwụ nje ndị na-esonụ:

• "Amoxicillin" ma ọ bụ "Flemoksin Soljutab" - penicillin otu, na-adabara ọtụtụ ná ndị ọrịa na-adịghị na-atụ aro maka ojiji n'oge ime, gbasara akụrụ odida.

• "Amoxiclav" - a Nchikota amoxicillin na kavulonovoy acid, na broadest ụdịdị dị iche iche nje na-atụ aro ndị dị akọ nke ahu were ya na akụrụ onye ọrịa ahụ pathologies, n'oge ime na ọgwụ nje na-akpata oké dysbiosis.
• "Clarithromycin" ma ọ bụ "Klatsid" - ala na-egbu egbu nje erythromycin otu dịgasị iche iche nke ndị kasị ewu ewu maka nditre, na-contraindicated na ụmụ ọhụrụ ruo ọnwa isii, ụmụ nwaanyị dị ime, eji na-ekwesịghị na ọrịa na gbasara akụrụ ma ọ bụ hepatic insufficiency.
• "Azithromycin" - onye ọzọ "Klaritomitsinu" na di ntakiri mmetụta, Otú ọ dị, ọ bụ obere irè megide helicobacter pylori.

Ọgwụ nje "tetracycline" na "Levofloxacin" na-eji obere mgbe n'ọnọdụ ndị ahụ ebe n'elu-e kwuru ọgwụ ọjọọ na-adịghị chọrọ N'ihi. Formulations tetracycline otu ngosi ike ike edinam na okwu nke mmetụta mgbe nditre Helicobacter, ya mere adịkarịghị eji.

Antibacterial na mgbochi infective ọgwụ maka nditre

"Metronidazole" - mgbochi infective chemotherapeutic gị n'ụlọnga nitromidazolovoy otu, nnọọ na-egbu egbu, nditịm ekwekọghịkwa mmanya na machibidoro iwu n'oge ime.

"Makmiror" ma ọ bụ "Nufuratel" - ihe antibacterial ọgwụ, ọ na-eji bụrụ na nke ọdịda nke "Metronidazole".

Vismutosoderzhaschie ọgwụ

"De-Nol '- nke a bụ ihe na nkà mmụta ọgwụ gosiri kasị elu ogo iche n'ebe Helicobacter. "De-Nol 'dissolves na-abatakwa bile slime sikwa ele n'ígwé nke emetụtara ngwa. Na-adịghị mma mmetụta nwere fọrọ nke nta ọ bụla, nakwa dị ka contraindications (ma e wezụga, omenala, ime).

Naa na-eji na ọgwụgwọ nke Helicobacter nnu bismuth ogige:

• bismuth subsalicylate;
• bismuth subnitrate.

Preparations dabere na bismuth salts eji maka ọgwụgwọ nke eriri afọ ọrịa, n'ihu oghere nke Helicobacter pylori. A ogige na-eguzogide ọgwụ na acidic na gburugburu ebe obibi nke afo. Bismuth ogige na mucosa mebiri emebi elu na-etolite a na-echebe film si corrosive gburugburu ebe obibi, ibelata acidity na-akwalite n'oge n'ichihịa nke metụtara na-ebupụta.

Mgbe ị mepee Helicobacter pylori bismuth ogige gosiri a pụtara utịp ke suppression na mbibi nke a akpan akpan bacteria.

Formulations olulu otu eji maka nditre

proton mgbapụta inhibitors (PPIs) dị oké mkpa na mgbagwoju mmetụta Helicobacter pylori. Mba ọgwụ ọjọọ nwere nke antacid mmetụta, ebelata ihe ike nke acid gburugburu ebe obibi. Nje bacteria Studies gosiri na nke acidic gburugburu ebe obibi ya na-anwụ. N'ihi ya, mba ike na-apụghị ịnagide ọnọdụ ala adị nke bacteria na a mgbagwoju na bismuth, "metronidazole" na ọgwụ nje na-abawanye ihe ịga nke ọma nditre Helicobacter pylori 95% na n'elu. A ọgwụ na-agụnye:

• "Omez" ( "omeprazole");
• "Nolpaza";
• "Rabeprazole";
• "Pantoprazole" na otú pụta.

ya bụ "Omez" kenyere ọzọ mgbe. Blockers ma ọ bụ proton mgbapụta mba slows ala-arụ ọrụ nke secretion nke digestive glands.

Normalisation nke digestive tract microflora mgbe nditre Helicobacter

N'ebe ọgwụ nje ọtụtụ mgbe, bụ detrimental ka eriri afọ na afo. Ya mere, mgbe nditre usoro mkpa iwelata mmebi kpatara nke ahu. Iji mee nke a, e nwere uru ngwaahịa ndị dị otú ahụ dị ka probiotics ma ọ bụ prebiotics, e gosiri na dysbacteriosis, flatulence, afọ ọsịsa, wdg a na-agụnye .:

• "Laktoferon";
• "Linex";

• "Hilak Chiefs";
• "Bifidumbacterin";
• "Atsipol" na otú pụta.

Probiotics na Prebiotics - a fundamentally dị iche iche omenala, n'otu complementing onye ọ bụla ọzọ ọrụ. Òtù abụọ ndị nwere a mmetụta bara uru na organism site normalizing nsia osisi. Ihe dị iche n'etiti ha bụ na probiotics - bi omenala bara uru microorganisms. Prebiotics otu - organic chemical ogige. The mbụ na-na "na-eto eto" a nwụrụ anwụ microflora, nke abụọ - mepụta mma ọnọdụ maka nke a. Ha maa mkpa iji mgbe nditre.

ọrịa mgbochi

Helicobacter pylori latent ụgbọelu nwere ike ọ bụla. The microorganism bi na afo, eriri afọ na onu oghere nke a mmadụ ma ọ bụ anụmanụ ihe karịrị afọ na-adịghị na-egosipụta onwe.

Ebighị nke bacteria emee ruru otu dịghịzi ọdịda n'okpuru nchegbu, na-emerụ àgwà (mmanya, ise siga), ekwesịghị nri na epigastric mgbu-egosipụta onwe ya. Ufodi Helicobacter pụrụ imetụta imeju.

ọgwụgwụ

Ofufe site media ọrịa emee site na kọntaktị ma ọ bụ site n'iji nke ụlọ isiokwu. Ị ga-akpachara anya na-eso iwu nke idebe onwe ha ọcha, iji iwelata ofufe nke a na-atọ ndị ọzọ ahụ. Mgbe ahụ, ọ na-adịghị achọ nditre Helicobacter pylori.