Nkwadebe "Prosulfin": ntụziaka maka iji, nyocha na analogues

Medicine "Prosulpin 'ntuziaka maka ojiji na-positioned dị ka a dị ike antipsychotic ọgwụ na-eji na ọgwụgwọ nke dị iche iche na-anaghị ekwe nke ụjọ usoro na ọrịa ndị ọzọ. More nkọwa banyere n'elu nkwadebe, na-agụ na.

Short nkọwa nke nkwadebe

A ọgwụ bụ ìgwè nke nnọchianya -benzenamine. Ụzọ ọzọ, anyị nwere ike ikwu na a bụ ahụkarị antipsychotic ọgwụ "Prosulpin". Ọbịa ọkachamara na-ekwu na ya edinam iji na igbochi dopamine anabata (D2i D3). N'ihi na e hotara na mbụ antipsychotic ọgwụ na-arụpụta a ọgwụgwọ mmetụta.

50 ma ọ bụ 200 mg nke otu mbadamba nwere sulpiride "Prosulpin" nkwadebe.

Mmetụta mgbe na-ewere ọgwụ, N'ezie, ime na ụfọdụ. Ya mere, a ọrịa n'oge ọgwụ n'elu antipsychotic kwesịrị n'okpuru ike ike na-elekọta.

Nke a na nkà mmụta ọgwụ nwere ọtụtụ iche-iche. Na ọ bụ dị mbadamba ụdị na ụdị capsules, a ngwọta maka intramuscular nlekọta na mmiri mmiri maka ingestion.

The ọgwụ kwesịrị echekwara na nkịtị ụlọ okpomọkụ ma ọ bụghị dị elu karịa 25 degrees Celsius. The ebe ga-ọma-echebe site na ìhè na mmiri. Fọrọ nke nta ka afọ abụọ nke adị ndụ "Prosulpin" ọgwụ ọjọọ. Analogues ọ bụghị ike ịchọta. Ọgwụ na ahịa a dịgasị iche iche nke ndị nọ n'ọnọdụ n'elu-e kwuru na ọgwụ ọjọọ.

The pharmacological edinam nke hotara na mbụ ọgwụgwọ gị n'ụlọnga

Medicine "Prosulpin" onye foto a nyere n'okpuru, bụ ihe antipsychotic gị n'ụlọnga na bụ a neuroleptic. sulpiride umi ruru igbochi nke dopamine anabata na tuberoinfudibulyarnoy region akwalite a ịrịba ama mmụba na prolactin etoju. Ọ ga-kwuru na na nso 60-80% ogo dịgasị igbochi dopamine anabata.

Nke ikpeazụ dị iche zuru ezu elu myirịta na benzamide, nke bụ ihe e ji mara ndị dị otú a mma ka bifazicheskoe utịp ke ọgụgụ akwara mbufe ozi dopamine usoro. Ọzọkwa, ha na-egbochi ndị na-abawanye na synaptic dopamine njikọ region, i.e. idomokoro presynaptic auto ihe nnabata D2 D3.

Ọ ga-kwuru na n'elu Nwa bụ moderately neuroleptic ọrụ. Nke ikpeazụ na-achọkwa na ọzọ timoanalepticheskim na-akpali akpali ihe nke ngwá ọrụ.

The n'elu ọgwụ nwere ndị na-esonụ pharmacological mmetụta:

• antiemetics (dopamine ihe nnabata mgbochi a rụrụ akpalite na vomiting center mpaghara);
• antidepressant;
• antipsychotic.

Sulpiride egosi antidepressant mmetụta na doses ruo 600 mg. N'elu ndokwa a esesịn a hụrụ antipsychotic mmetụta nke a ọgwụ na ahu.

Ke adianade do, ọgwụ ọjọọ, "Prosulpin" ntụziaka na-egosi na ọ na-amị a nhọrọ utịp ke hypothalamus, mgbaàmà nke gastric ọnyá afọ na gastroduodenitis. N'ihi ya ewute elu excitation emmepe nke ọmịiko ụjọ usoro, mma inweta ọbara afo, accelerated proliferation nke granulation anụ ahụ, Filiks nke imi secretion na afo, na-kpụrụ regenerated epithelium, mmụba nke capillaries mma anụ ahụ.

Ònye kwesịrị ibute a usọbọ?

Gịnị bụ ọgwụ "Prosulpin" na-egosi maka ojiji? Maka ọgwụgwọ nzube, na n'elu ọgwụ ọjọọ na-eji ndị dị otú ahụ ọrịa:

• psychosomatic ọrịa;
• nchegbu ọnyá nke digestive tract;
• symptomatic ọnyá;
• gastroduodenitis;
• afo ọnyá afọ;
• agbakasị bowel (colon);
• medicated ọnyá;
• nonspecific ọnyá afọ;
• Ịda mbà n'obi dị iche iche etymology;
• neuroses;
• reactive ịda mbà n'obi;
• dysphoric aghara;
• isi mgbaka;
• -adịghị ala ala ọrịa uche ;
• migraine;
• nnukwu nsogbu uche;
• vertigo dị iche iche etymology (vestibular neuritis, vertebrobasilar insufficiency, basilar, Meniere ọrịa, otitis media).

Drug "Prosulpin" ntuziaka maka ojiji na-enye na-etinye maka ọgwụgwọ nke akparamàgwà ọrịa na psychoses na-eto eto na-arịa ọrịa, ie ụmụ. Nke a ọrịa ndị dị otú ahụ dị ka onwe-bie ugwu, n'ahụhụ, stereotypes. Ọzọkwa na nkà mmụta ọgwụ "Prosulpin" ntuziaka maka ojiji insistently adụ ọdụ iji dị ka akụkụ nke a N'ezie nke ọgwụ nke ụmụaka autism. Nke a na ngwá ọrụ e ji na-emeso nwa ọrịa noo 6 afọ.

Contraindications ojiji nke hotara na mbụ ọgwụ

Drug "Prosulpin 'ntuziaka maka ojiji na-adịghị akwadoro ma ọ bụrụ na onye ọrịa nwere mgbaàmà nke na-esonụ ọrịa:

• hypersensitivity ọgwụ;
• hyperprolactinemia;
• prolaktinzavisimye etuto ahụ (ara cancer, pituitary prolactinoma);
• ọrịa uche;
• nnukwu nsi ọṅụṅụ na-ebu na-aba n'anya;
• ime ihe ike;
• pheochromocytoma;
• Nnukwu nsi site ọgwụ ọjọọ ma ọ bụ ọgwụ ọgwụ ụra;
• manic psychosis.

All ndị a na-ekwu bụ na nlezianya contraindications. Ọzọkwa na nkà mmụta ọgwụ "Prosulpin" ntuziaka maka ojiji na-amachibido inye ndị inyom ndị ara na-eri nri nwa ọhụrụ ha, ụmụ n'okpuru afọ 18 (n'ihi na 200 mg ọgwụ), na-eto eto ndị ọrịa ruo 6 afọ (50 mg ọgwụ).

Ke adianade do, ọ ga-eti, na-ekwesighi iji ọgwụ "Prosulpin" congenital erughi nke lactose, glucose-galactose malabsorption, lactose ekweghị ibe nọrọ. Contraindications na ojiji nke n'elu ọgwụgwọ mmadụ na-emetụtakwa ụmụ nwaanyị dị ime. Jiri ya maka ndị dị otú ahụ ọrịa na-kwere na ọ bụrụ na ndị na-atụ anya uru nke ọgwụ ga-abụ nnọọ elu karịa nwere ihe ize ndụ ka nke nwa ebu n'afọ si ya.

mmetụta

Mgbe inweta "Prosulpin" nkwadebe (ntuziaka na-egosi nke a), i nwere ike na-enweta ụfọdụ mmetụta:

• na na akụkụ nke endocrine usoro - galactorrhea, dysmenorrhea, amenorrhea, frigidity, enweghi ike;
• si akwara - ogwuura, mara jijiji, dizziness, n'oge dyskinesia, extrapyramidal syndrome, somnolence, akinesia na muscular hypertonicity, akathisia, moto excitation;
• ntọt ke ọrụ nke enzymes (si mgbaze);
• hemolytic anaemia, leukocytosis, aplastic anaemia, granulocytosis, purpura, thrombocytopenic ime na elu doses "Prosulpin" nkwadebe (site n'oru nke ọbara na Lymph systems);
• tachycardia, orthostatic hypotension, ebelata ma ọ bụ na ụba ọbara mgbali, amụba nkeji QT, na ụfọdụ na mmepe nke dị ize ndụ ọrịa ndị dị ka torsade des pointes syndrome (obi na ya usoro).

Ọzọkwa ime ka ndị ọzọ mmetụta a ọgwụ. Drug "Prosulpin" (ntụziaka nzaghachi dọkịta na ndị ọrịa Ibọrọ na-agba akaebe na nke a) pụrụ ịkpasu ndị dị otú ahụ wetara phenomena ka tardive dyskinesia, nke e ji ịsụ rhythmic mmegharị nke ihu ma ọ bụ ire (na a ogologo ọgwụgwọ N'ezie neuroleptics niile iche iche), hyperthermia. Ndị ọkachamara na-adọ aka ná ntị na ná ngwụsị ikpe dị mkpa karịsịa oge iji kagbuo n'elu n'aka, ebe ọ bụ na okpomọkụ ịrị elu ike indicative nke ndị dị otú ahụ dị ize ndụ ọrịa ndị dị ka neuroleptic ajọ syndrome.

Ibu ibu, mụbara sweating, anụ ọkụ ọkụ na itching - a niile mmetụta nwekwara ike ime ka ịṅụ ọgwụ ọjọọ "Prosulpin". Ntuziaka, kwuru ndị ọkachamara nwere ike ikwu na otú ahụ ikpe na-akwụsị na-ewere n'elu ọgwụ na-achọ ozugbo abiausọbọ maka enyemaka na ndụmọdụ.

Jiri n'oge ime n'elu ọgwụgwọ gị n'ụlọnga

Teratogenicity nke ọgwụ na a hụrụ dị ka a n'ihi nke anụmanụ nwere. Ụfọdụ ndị inyom bụ ndị na-eji nkà mmụta ọgwụ mgbe gị afọ ime, na ha edebeghị n'elu-e kwuru mmetụta. Ma ndị ọrịa a natara ala-dose putara "Prosulpin". Ntuziaka maka ojiji, ezigbo ndị ọkachamara na-adịghị kpọmkwem ozi banyere iji a elu ego nke a umi dị ka sulpiride. E nwekwara mba data na mmetụta nke hotara na mbụ Nwa maka mmepe nke nwa ebu n'afọ na ụbụrụ.

Dị ka a akpachara anya ọkachamara adịghị nye ndụmọdụ iji nke a ọgwụ maka ndị inyom na steeti. Ọ bụ ezie na mgbe ụfọdụ, ka kwere ka ọgwụgwọ nke n'elu-e kwuru nkwadebe nke ọrịa, ha na-atụ anya a nwa, ma nditịm na ntakiri doses.

Ndị ọkachamara kwuru na ọ bụrụ na nne na-anata neuroleptics ọgwụ ruo ogologo oge mgbe, a mụrụ nwa ọhụrụ crumbs nwere nsogbu na digestive tract ọrụ (eg bloating).

Ọ bụrụ na a nwaanyị na-eji ọgwụ ọjọọ n'oge tupu nnyefe, na-achịkwa ya na ahu na mmepe nke nwa ebu n'afọ site na a dibịa bụ amanyere bụ iwu.

Ọ ga na-ahụ na-echeta na-aga n'ime mmiri ara ọgwụ "Prosulpin". Ntuziaka maka ojiji, n'ezie ọkachamara adịghị ike ikwu na-ewere ya n'oge lactation.

Olee na-ọgwụ ọjọọ, "Prosulpin"?

Guide awade ọrịa na-eji n'elu antipsychotic 8 ọ bụla awa na a otu Erere. Adịghị atụ aro ka na-na nkà mmụta ọgwụ mgbe 16,00, dị ka ya ọrụ bụ ezigbo enwekwu n'oge a. Ọ ga-kwuru na-eji n'agbanyeghị nke nri na asa ala na a zuru ezu ego nke a mmiri mmiri nkwadebe "Prosulpin".

Mbadamba na-ebu 200 mg nke sulpiride, anabatara nnukwu mgbaàmà nke isi mgbaka, delirious psychosis na ịda mbà n'obi. The ọgwụ nwere ike iwere na kewara doses. Ya kacha kwa ụbọchị dose bụ 100 mg, ma ọ bụ banyere 5 mkpụrụ ọgwụ.

Mbadamba, nke na-agụnye 50 mg nke sulpiride, awade ntụziaka na-, ma ọ bụrụ na onye ọrịa nwere mgbaàmà nke neurosis, nchegbu. N'ime 4 izu, ndị ọrịa a na-eri ihe a kacha nta nke otu na a kacha nke 3 mbadamba a ụbọchị.

Ọzọkwa, mkpụrụ ọgwụ ndị a nwere ike iwere maka ụmụaka na oké-akpa àgwà ọjọọ. The afọ nke ndị dị otú ọrịa mgbe niile kwesịrị ịbụ elu karịa 6 afọ. The kacha kwa ụbọchị dose maka ọrịa a, Atiya bụ site 5 na 10 mg kwa 10 n'arọ ahu aro.

ovadozu

Manual na-egosi na ovadozu sulpiride ọmụma dị nta. Ndị na-esonụ mgbaàmà nwere ike hụrụ ọnọdụ a na a ọrịa:

• ire protrusion;
• dyskinesia na spasmodic torticollis;
• bịara ikiri ọhụụ;
• akọrọ ọnụ;
• kwere omume mmepe nke NSAs;
• extrapyramidal mgbaàmà;
• ụba sweating;
• ọgbụgbọ;
• ogwuura;
• gynecomastia;
• Ọrịa Parkinson;
• ntọt ke ọbara mgbali.

Ọgwụgwọ nke n'elu ala nke onye ọrịa a rụrụ dị ka ndị a:

• saa afo nke onye ọrịa ahụ;
• họpụtara ndị ọrụ carbon;
• a Ịhazi ọgwụ.

Ọ bụrụ na ọ dị mkpa, na oké ikpe, ndị dibịa nwere ike nye iwu ka ọzọ aghụghọ, dị ka diuresis infusion ngwọta nke alkali ma ọ bụ nyochaa mkpa aru ọrụ.

Ọ ga-kwuru na nke a nkwadebe na-ewepụtara nwere obere na hemodialysis.

Ụfọdụ na edemede nke ọrịa ga-pụrụ iche anya mgbe eji "Prosulpin" ọgwụ ọjọọ. Nke a na-emetụta isi inyom na oge ufodu oge, ọrịa na oké hypotension na ọbara mgbali.

Ọ dịkwa mkpa ka ọrịa na Akwụkwụ na-adọ mbido electrophysiological na-adakarị nnyocha. Ọ ga-eti na ọgwụ "Prosulpin" lowers fọrọ maka ọdịdọ ọrụ.

Ọzọkwa, mgbe ụgbọala iga chọrọ pụrụ iche na-elekọta n'oge ọgwụgwọ na n'elu ọgwụ ọjọọ. Ọ dịkwa mkpa amachi eme ihe ndị chọrọ ngwa ngwa psychomotor Jeremaya mere na akwa ịta.

Mmekọrịta ndị ọzọ ọgwụgwọ mmadụ

Ntuziaka na-adịghị erube nnọọ na-atụ aro na n'elu-e kwuru ọgwụ na jikọtara ọgwụ na levodopa. The abụọ arụ ọrụ bekee na-akụ ọkpọ. Ọ bụrụ na a-enwe ndidi, na-arịa ọrịa Parkinson, na-ewe levodopa, ndị dibịa bụ gị n'ụlọnga ga-ahọrọ nwere a ntakiri extrapyramidal mmetụta.

Arrhythmias dị ka torsades de pointes nwere ike mere site na a Nchikota "Prosulpin" ọgwụ ọjọọ na:

• antiarrhythmic ọgwụ ọjọọ, nke nwe klas IA (ọgwụ ọjọọ "Dizopiramid" "quinidine");
• ọgwụ ọjọọ "pimozide," "Haloperidol", "thioridazine" "Cisapride", "Pentamidine" imipraminovymi antidepressants;
• antiarrhythmic ọgwụ ọjọọ na-gụnyere ke klas nke atọ (pụtara "Sotalol", "Kakamiodaron");
• ọgwụ na-eme ka ihe mgbaàmà nke ọrịa ndị dị ka bradycardia (beta-blockers, calcium ọwa blockers);
• ọgwụ ọjọọ na-eme ka ọdịdị nke ihe ịrịba ama nke hypokalemia (laxatives na-stimulatory, hypokalemic diuretics, tetracosactide, glucocorticoids);
• dopamine akụ ọkpọ (antiparkinson): "apomorphine", "Amantadine" "Lisuride", "Ropinirole", "Entacapone" "Bromocriptine", "selegiline" "Pramipexole" "Piribedil");
• antipsychotic ọgwụ ọjọọ nwere ike na-eme ka ihe mgbaàmà nke torsades de pointes ( "Chlorpromazine" "Amisulpride," "Tsiamemazin" "pimozide," "Droperidol" "levomepromazina" "tiapride," "Sertindole" "Veraliprid" "Sulpiride") ;
• ọgwụ ọjọọ na-ebu lithium (nke ikpeazụ nke ukwu enwekwu ihe ize ndụ nke extrapyramidal ọrịa).

Ọzọkwa, ọ bụla ikpe, ọgwụ "Prosulpin" kwesịghị eji na njikọ na-aba n'anya. Ikpeazụ potentiates na ogwuura utịp neuroleptics.

Ke adianade do, ma ọ bụrụ na anyị na-n'elu-e kwuru ọgwụ na Nchikota na centrally na-akpali akpali bekee (mgbochi asthmatics, anorectics), onye ọrịa nwere ike mgbaàmà nke ike excitation, ịma jijiji, nchegbu, nchegbu.

Ọ ga-eti na antipsychotic ọgwụ lowers larịị nke irè nke ropinirole.

Nọ n'ọnọdụ "Prosulpin" ọgwụgwọ gị n'ụlọnga

Analogs nke n'elu antipsychotic:

• "Betamak T100";
• "Vero Sulpiride";
• "Betamax T50";
• "Depral";
• "Betamax";
• "The malitere izi ozizi nke";
• "Betamax T200";
• "Sulpiride";
• "Eglonil";
• "Sulpiril";
• "Eglek".

Ma gbanwere enweghị tupu oge na dọkịta adịghị ike ikwu "Prosulpin" ntụziaka ntuziaka. Ya analogues nwekwara ha n'otu n'otu mmetụta. Ha nwere ike mee ka oké nsogbu na ọrịa ahụ ike.

Ibọrọ nke ọgwụ na ahụ ike pụtara "Prosulpin"

Nyocha nke n'elu na nkà mmụta ọgwụ na-akasị mma. A ọtụtụ ndị ọrịa na-ewere ya na obi dara ya mbà na-ekwu. Ha na-ekwu na ngwá ọrụ a na-enyere aka iwepụ ihe ndị mgbaàmà nke ọrịa bụ fọrọ nke nta 100%.

Ọzọkwa, ọtụtụ ndị ọrịa zuru ezu na-azaghachi, nke na ọrịa ndị dị ka isi mgbaka, enterocolitis, afọ, psychosis, enteritis, ọnyá ọrịa, agbakasị bowel syndrome, were ọgwụ "Prosulpin". Nyocha nke na-egosi na mgbe nile, na ngwá ọrụ na-arụpụta ihe ịrịba na-agwọ ọrịa mmetụta. Ke adianade do, ọrịa na-akọ na mmetụta ime nnọọ adịkarịghị.

The n'elu ọgwụ nwere oké njọ mmetụta, n'ihi ya, jiri ya na-enweghị tupu oge na dọkịta na-nditịm ajuru aju.