Ọgwụ "Roxithromycin": ntuziaka maka ojiji, nkọwa, analogs, reviews

Na ụfọdụ ọrịa ndị dose kenyere "Roxithromycin"? Ntuziaka maka ojiji nke mbadamba ga-akọwara dịrị gaba n'ime ebe. Ọzọkwa si isiokwu ị ga-amụta otú ihe ndị a ọgwụ, ma ọ bụrụ na o nwere ọ bụla analogues, ihe bụ mmetụta na contraindications.

Mejupụtara, nkọwa, ọgwụ ụdị

Mbadamba "Roxithromycin" film mkpuchi, na-acha ọcha na gburugburu na biconvex udi kanyere "164".

The n'ọrụ mgwa nke ọgwụ bụ roxithromycin. Ke adianade do, ọgwụ na-agụnye inyeaka mmiri dị ka giproloza, povidone K30, poloxamer, magnesium stearate, colloidal silica, ọka starch na talc.

Banyere film mkpuchi, na ọ nwere hypromellose, dextrose, propylene glycol na titanium dioxide.

The ire ọgwụ ọnọ ke ọnya Ukwu na katọn karị.

The pharmacological e ji mara ọgwụ nje mbadamba

Gịnị bụ mmetụta na ozu na nkà mmụta ọgwụ "Roxithromycin"? Ntuziaka maka ojiji nke na-ekwu na bụ a semisynthetic ogwu mgbochi, nke ìgwè nke macrolides, nke nwere a dịgasị iche iche nke ọgwụ nje ọrụ.

The agwọ ọrịa nwere bacteriostatic edinam. Ọ na-ejikọ na 50s ribosomal subunit, onye na-adịghị ribosome protein njikọ, na-egbochi transpeptidation mmeghachi omume na translocation, nakwa dị ka usoro nke bonding n'etiti peptide yinye na amino asịd. Ndị dị otú ahụ pụrụ isi kwuo akwalite mgbochi nke ibu na mmeputakwa nke bacteria.

Ọgwụ nje "Roxithromycin" penetrates ọma ma na ngwa ngwa n'ime mkpụrụ ndụ, nke ana achi achi na ya elu nrụpụta megide intracellular pathogens.

Pharmacokinetics nke ọgwụ

Ebe absorption nke "Roxithromycin" ọgwụ ọjọọ? Ọbịa ọkachamara na-akọ na mgbe onu ochichi nke agwọ ọrịa a na-etinye obi gị dum na eriri afọ tract.

Mbadamba bụ ufọk ufene ke acidic na gburugburu ebe obibi nke afo. Food, ọgwụ site ¼ awa mgbe agwọ ọrịa enweghị mmetụta na ya absorption.

Mgbe anata ya kacha ọgwụ ịta enweta mgbe ọkara awa abụọ.

Iji nke ọgwụ na awa 13 na otu nkeji ekwusi achọrọ kasịnụ nke ọgwụ na ọbara n'ụbọchị.

Communication na plasma-edozi bụ 95,5%. Na nke a, ọgwụ n'ime akpa ume, prostate Gland na tonsils. Ọzọkwa e nwere ya sel (macrophages) na dị iche iche na mmiri ahụ.

"Roxithromycin", ego nke nke na-depụtara n'okpuru ebe, fọrọ ọ dịghị banye ọbara-ụbụrụ mgbochi na ọ na-anyụpụ na mmiri ara naanị obere obere. N'agbanyeghị nke a, were nke a ọgwụ ọjọọ n'oge ndị dị otú ahụ bụ ihe amachibidoro.

The ọgwụ na-ikpe metabolized na imeju. Ya kasị ukwuu hà (banyere 50%) na-anyụpụ agbanweghi agbanwe na eriri afọ na site na akụrụ (ihe dị ka 12%) na ìhè (15%).

The ọkara ndụ-nke nọ n'ọrụ umi mgbe a otu dose bụ mkpokọta 13 awa.

kacha ịta na ọkara ndụ nke ọgwụ na-abawanye na ndị ogbenye na imeju ọrụ.

egosi ogwu mgbochi

N'ihi na ihe na nzube kenyere "Roxithromycin" mbadamba? Ntuziaka maka ojiji na-ekwu na nke a gị n'ụlọnga irè na-emeso na-efe efe na-kpatara susceptible pathogens na-arụsi ọrụ ike umi.

Adult ọgwụ kenyere ikom:

• tonsillitis, pharyngitis, nnukwu Sinusitis;
• adụ anụ ahụ na-efe efe, na akpụkpọ;
• oyi baa, bronchitis;
• urinary tract-efe efe;
• na-efe efe na dentistry (ezé na onu oghere).

"Roxithromycin" kenyere ụmụ:

• pharyngitis, tonsillitis, nnukwu Sinusitis;
• oyi baa, bronchitis;
• adụ anụ ahụ na-efe efe na akpụkpọ.

Contraindications na ojiji nke ọgwụ nje gị n'ụlọnga

Mgbe ụfọdụ, ọrịa na-adịghị nye iwu ọgwụ "Roxithromycin"? Ntuziaka maka ojiji dị ka ndị na-esonụ ukpan:

• Mụbara uche na-enwe ndidi macrolides roxithromycin ma ọ bụ na dum, nakwa dị ka ndị ọzọ bekee nke Nwa;
• porphyria;
• n'oge ime;
• Imekotaotuugbo n'ikuku na "cisapride", "terfenadine," "pimozide" na "Astemizole";
• arọ ahụ erughị 40 n'arọ;
• ara;
• mgbagwoju were vasoconstrictive ergot alkaloids (ergotamine na dihydroergotamine);
• afọ 12 afọ.

Nlezianya ochichi nke mbadamba

Drug "Roxithromycin", nke analogues ga-ọkọnọ n'okpuru, na ịkpachara anya kenyere ndị na hepatic ma ọ bụ gbasara akụrụ insufficiency, agadi ọrịa, na ọrịa na ọnọdụ na-eme ka obi n'afọ iri na ụma na-anaghị ekwe, na congenital prolongation nke QT oge.

The onunu ogwu nke ọgwụ ndị okenye na ụmụaka

Mbadamba kenyere n'ime tupu a nri. N'ihi na ndị okenye na ụmụaka okenye karịa afọ 12, ọkọlọtọ onunu ogwu bụ 150 mg nke ọgwụ ugboro abụọ n'ụbọchị na etiti oge nke 13 awa ma ọ bụ 300 mg dose (n'ihi na ndị okenye).

Ndị agadi ndị na kwa ụbọchị ma na a otu dose ọgwụ adịghị agbanwe. Ọrịa na gbasara akụrụ insufficiency ọgwụ na-ndinọ na a dose nke 150 mg ugboro abụọ n'ụbọchị.

Ọrịa na mmebi imeju onunu ogwu na-belata ọkara (150 mg otu ugboro n'ụbọchị).

Na oge nke ọgwụgwọ nke ndị okenye na ụmụaka

Ogologo oge ọ ga-ewe ọgwụ "Roxithromycin"? Na oge nke ọgwụgwọ na-adabere na-egosi, nakwa dị ka a microorganism nke mere ka ọrịa, na ogo nke ọrịa.

Okenye, ọkọlọtọ ọnụego nwere ike buru banyere 5-10 ụbọchị. Na-efe efe na-mere site na beta-hemolytic streptococcus, ọgwụ ga-adịru dịkarịa ala ụbọchị 10.

N'ihe gbasara ụmụ, oge nke N'ezie ha na-5-10 ụbọchị.

Overdosing agwọ ọrịa

Na elu doses nke ọgwụ a ndidi nwere ike ụba dose metụtara mmetụta. Dị ka ọgwụgwọ nke ọnọdụ ndị dị otú iji symptomatic ọgwụ na gastric lavage.

mmetụta

Mgbe na-ewere echiche nke ọgwụ na onye ọrịa nwere ike na-egosipụta na-esonụ mmetụta:

• ọgbụgbọ, abdominal mgbu, vomiting, afọ ọsịsa, pseudomembranous afọ, pancreatitis;
• ụba ọrụ nke imeju transaminases, nnukwu hepatocellular ma ọ bụ cholestatic ịba ọcha n'anya;
• paraesthesia, dizziness, mgbanwe uto, isi ọwụwa, disturbances ísì, na-anụ na ọnwụ bụ ruo nwa oge, ịmụ anya arọ nrọ, vertigo, Gipoakuzija;
• nācha ọbara-ọbara, ihe ọkụ ọkụ, purpura;
• angioedema, bronchoconstriction, urticaria, eosinophilia;
• anaphylactic ujo, erythema multiforme ;
• superinfection, candidiasis.

kpọmkwem na-atụ aro

Ndị na-imeju ọdịda ọgwụ họpụtara na oké ịkpachara anya.

Na mmepe nke nfụkasị Jeremaya mere na superinfection ọgwụ ga-kwụsịrị na onye ọrịa na-enweta ọgwụgwọ kwesịrị ekwesị.

Mgbe anata ọgwụ, nakwa dị ka abụọ ka izu atọ mgbe omume, onye ọrịa nwere ike ịzụlite afọ ọsịsa mere site pseudomembranous afọ.

Drug "Roxithromycin" na-aba n'anya na-aju ikpokọta.

ọgwụ interactions

E lee ya anya ọgwụ na-adịghị ndinọ na ọgwụ ọjọọ na-ebu ergotamine, dihydroergotamine, ma ọ bụ, dị ka ọ nwere ike ime ka ọbara spasm.

Ejila "Roxithromycin" na a "terfenadine" ruru ka na-amụba ihe ize ndụ nke nsogbu nke obi usoro.

Ọnụ na mbanye nke ọgwụ na "digoxin" nwere ike ntọt ya absorption, nke ga-eduga mmepe nke glycoside igbu egbu.

The Nchikota "Cyclosporine" ma ọ bụ "theophylline" na "Roxithromycin" nwere ike ime ka ụba plasma kasịnụ nke ikpeazụ.

Analogs agwọ ọrịa

The kasị ewu ewu na analogue "Roxithromycin" bụ "Erythromycin". Guide na-ekwu na nke a nkwadebe bụkwa ihe ude.

Ya mere nke a ngwaọrụ mma? Tụnyere "erythromycin" "Roxithromycin" nwere ihe ndị ọzọ mma pharmacokinetic Njirimara. Ịgbaso onu ochichi, ọ bụ nnọọ ihe ngwa ngwa etinye obi gị dum na eriri afọ tract.

Na elu ndị ọzọ bioavailability, nke bụ weakly dabere na nri oriri, ọgwụ ahụrụ n'ime ọbara ugbua na ¼ awa mgbe.

Ọ kwesịkwara kwuru na ọgwụ "Roxithromycin" Nleta a ọzọ gbara ọkpụrụkpụ na-na a pụrụ ịdabere ịta, bụghị naanị na mmiri ahụ na anụ ahụ, ma na-na ọbara ọbara.

N'ihi ya, ọ nwere ike n'enweghị-ahụ kwuru na mbụ ọgwụ abụọ ta njọ. "Erythromycin", nke ntụziaka a na-agbakwunyere na a kaadiboodu igbe, bụ gharazie ịba uru ude.

Ke adianade kwuru n'aka, ọgwụ ọjọọ, "Roxithromycin" nwere ike dochie anya na ndị dị otú ahụ ọgwụ ọjọọ eme ihe dị ka "Brilid", "Esparoksi" "Vero Roxithromycin", "Elroks", "Ksitrotsin", "Rusbrikar", "Remora", "Rulitsin", " Rokseptin "," Rulid "," RoksiGEKSAL "," Romik, "" Roksid "," Roksolit "," Roksilor "" Roxithromycin DS "," Roksimizan ".

price ọgwụ

Ole bụ ọgwụ nje "Roxithromycin"? The price nke a ọgwụ bụ nnọọ elu. Ịzụta ya na pharmacies nwere ike ịbụ n'ihi 550-600 rubles.

Nleba banyere nkà mmụta ọgwụ

Ọgwụ nje "Roxithromycin" - a mara mma na-ewu ewu ọgwụ n'etiti ọrịa. Ya mere, e nwere nnọọ ọtụtụ kwuru banyere ngwá ọrụ a. Ọtụtụ ndị na-akọ na ọgwụ na-akpa àgwà dị ka a nnọọ irè ogwu mgbochi ọgwụ. Nchikota na ọgwụ ndị ọzọ ọ na-akpata ịlụ ọgụ dị iche iche na-efe efe nke elu na nke ala akụkụ okuku ume na tract (tonsillitis, pharyngitis, nnukwu Sinusitis), na urogenital tract, adụ anụ ahụ na akpụkpọ.

Yana mma nzaghachi si ngwá ọrụ a dị na-adịghị mma. Ọtụtụ mgbe, ndị ikpeazụ metụtara na mmetụta na-erukwa na ọrịa na-anata ọgwụ na-atụle. Ụfọdụ ọrịa mkpesa nke ọgbụgbọ, oké afọ ọsịsa, isi ọwụwa, vomiting, pancreatitis nkpasu-iwe na ọkụ ọkụ.

Mgbe ị na-ahụ ndị a mgbaàmà, ndị dọkịta nwere ike ikwu na-ekweghị anabata mbadamba na-ahụ a dọkịta, bụ onye na iwu ji ya nye ndụmọdụ a odi mfe ọgwụ.

Ọ kwesịkwara kwuru na e nwere ndị a otutu reviews na ọgwụ nwere ihe ebu na-eri. Ọrịa na-ekwu na analogues nke a pụtara na e nwere ọtụtụ dị ọnụ ala karịa na mgbe ọ bụghị nnọọ ala karịa ya irè.