"Poliglyukin": ntuziaka maka ojiji, contraindications, reviews

"Poliglyukin" - antishock plazmozameshchath agwọ ọrịa mmemmem replenishing nke Bcc. N'ihi ya, na ojiji nke ọgwụ ọjọọ na-gbochiri adhesion nke platelet na mkpụrụ ndụ ọbara uhie.

Mejupụtara gụnyere "polyglukin"

Ndabere nke ọgwụ - dextran. Na karama nwere 200 na 400 ml nke nkwadebe n'ụdị otu okenye ihe ngwọta. The ọgwụ mejupụtara nwere sodium chloride na mmiri ogwu ogbugba.

pharmacodynamics

"Poliglyukin" ntụziaka na ngosipụta dị ka a na nkà mmụta ọgwụ na-enwe antiagregatnym na hemodynamic mmetụta. The ọgwụ bụ a hydrophilic polysaccharide nkịtị mmiri. Mgbe iji ọgwụ Bcc weghachiri a obere oge n'ihi na eziokwu na ọ na-amịkọrọ mmiri zuru ezu.

N'ọrụ akụrụngwa nwere a dịtụ elu molekụla ibu, otú ke n'ọbara ọ bụ ugbu a n'ihi na a ogologo oge, na na na-adọ nwayọọ nwayọọ na-aga site na arịa mgbidi. Atụmatụ nke ọgwụ ngwa ngwa dịkwuo na ogologo na-ọbara mgbali nkịtị. "Poliglyukin" ebelata anụ ahụ edema, eweghachi Bcc eliminates spasm, nke pụtara na elu arịa.

Suspension kwụsie ike na-akakwa mma ọbara mgbe omume "Poliglyukin" ntụziaka na-egosi na ọgwụ na-eme ka ọbara na-erughị viscous. Na ụmụ mmadụ, normalized ọgụgụ, agbajikwa n'ihi na mmepe nke ujo: microcirculation, ọbara na anụ ahụ.

Pharmacokinetics

Excretion nke agwọ ọrịa na-emepụta si ahụ tumadi site na akụrụ ya. Ele Mmadụ Anya n'Ihu mwepụ a rụrụ n'ụbọchị. "Poliglyukin" wepụrụ emebibeghị, ntakịrị òkè-ya nile abatakwa sel nke reticuloendothelial usoro na na-edebe e ji nwayọọ nwayọọ na-adị gbawara agwọ ọrịa. N'ihi na nke a usoro, glucose na-emepụta, nke a na-emeghị ihe dị ka isi iyi nke ike. Little "polyglukin" odụk digestive tract.

na-agba akaebe

"Poliglyukin" ntụziaka na ngwa-enye gị ohere ekenye mgbe agbajikwa capillary ọbara. The ọgwụ kwesịrị ekwesị maka ọgwụgwọ nke na-ekwu nke ujo na Mgbochi (septic ujo, na-egbu egbu, Burns, arụmọrụ, traumatic). A ọgwụ eji na nnukwu ọbara na ọnwụ nke mere n'oge ectopic afọ ime, na-amụ nwa ma ọ bụ dị ka a n'ihi nke trauma ngwa ngwa weghachi Bcc. Ngwọta bụ hypovolemia, nke bụ na ya pụta nke plasma leakage (ogige syndrome, Burns). Irè nke ọgwụ a hụrụ na mmejuputa mgbochi iji na-egbochi embolism (preoperative, postoperative).

contraindications

Tupu ọgwụgwọ ọ dị mkpa ntị ka contraindications, nke nwere ihe mgbakwunye na owuwu "Poliglyukin" ntụziaka ntuziaka. Contraindications maka ọgwụgwọ na mgbochi nke nkwadebe a dị ka ndị a:

• ọrịa ụbụrụ strok;
• High ICP;
• na-ekwu na nke iwebata mmiri na nnukwu quantities bụ ekwesighi;
• ọrịa so site gbasara akụrụ ọrịa (anuria, oliguria);
• oké ọbara mgbali;
• obi odida;
• ọrịa nke homeostasis, coagulation;
• nọgidere na ọbara ọgbụgba (isịneke - ọbara mgbali n'okpuru 60 mm HG ..).

Ọnụọgụ ọgwụ ọgwụgwọ

A ngwọta maka igba ogwu n'akwara ochichi. N'ọnọdụ ebe ọbara na ọnwụ na-ewere nnukwu, ọ kwere na ojiji nke intra-ọbara ọgwụ. Ọnụego nke ọgwụ ochichi na-kpebisiri ike n'otu n'otu na-adabere na izugbe ọnọdụ onye ọrịa, ya obi ọnụego, ọbara mgbali na hematocrit.

Site ujo na-ekwu, "Poliglyukin" ntụziaka ntuziaka aro ndinọ bolus igba ogwu n'akwara ụzọ. The chọrọ otu dose of mmadụ dị otú ahụ ikpe bụ ihe na-erughị 400 ma ọ bụghị ihe karịrị 1200 ml. N'ọnọdụ ụfọdụ, ọ dị mkpa ka iwelie dose ọgwụ ruo 2000 ml. Ọ bụrụ na arụmọrụ nke BP dị ka a n'ihi nke ochichi nke ọgwụ ike ime ka nkịtị, a ntughari ka iwebata ọgwụ ụmụ irighiri mmiri.

Na ịrịba ọbara ọgbụgba, nke kwekọrọ na 500 ml na ndị ọzọ, nakwa dị ka ọnụnọ nke oké anemizatsii ma e wezụga na-eji "polyglukin" ihe ngwọta na-rụrụ mịnye. Dị ka a mgbochi ụfọdụ iji gbochie ujo n'oge ịwa ahụ ọgwụ ndinọ na-atasị mgbe nsogbu adawo - ugboelu. The nkọ iju ke ọbara mgbali 60 mm HG. Art. na n'okpuru-achọ iwebata "polyglukin" na a olu adịghị aka 400 ml intraarterially. Mgbe n'ịrụ arụmọrụ-eji nke a na nkà mmụta ọgwụ mepụtara mgbochi, ikwe iji gbochie mmepe nke na-akpata.

ngwọta na a na-eji na a ịta nke 6% ifịk umi, ma na-emetụta "Poliglyukin 33" na ụfọdụ. Ntuziaka maka ojiji na-egosi na Nwa na a ịta nke dextran bụ inyeaka reagent mgbe ịlele ndakọrịta nke nnata ma na-enye onyinye.

Mgbe ọ dị mkpa iji kpochapụ apa ọkụ ujo, n'ụbọchị mbụ na onye toro eto na-ndinọ site 2 puku. Puku na 3. ml ngwọta, na-etinyere na ụbọchị nke abụọ nke karịa 1.5 puku. Ml nkwadebe. Na ndị ufodu mgbe ujo dị mkpa iji wepu nwa, ọ na-mbụ ndinọ 40-50 ml / n'arọ n'aka, n'ụbọchị nke abụọ ndị dose kwa kilogram arọ ahụ na-ebelata ka 30 ml. Dị ka a mgbochi ụfọdụ, iji kpochapụ-ekwe omume nke ujo, na umu-ịme ntapu igba ogwu n'akwara ụzọ. The chọrọ dose maka a nwa àmà site 10 ruo 15 ml / n'arọ "Poliglyukin" nkwadebe. Ntuziaka maka ojiji maka ụmụ anụmanụ, kwa, na-eme ka o kwe omume na-eme na ọgwụgwọ, dabeere na iwebata "polyglukin". N'ihi na ndị a na nzube ngwọta dose nke 15 na 20 ml / n'arọ. The kasị kwesị ekwesị dose nke ọgwụ kpebisiri ike site dọkịta.

mmetụta

N'ihu iji ngwaahịa "Poliglyukin 'ntuziaka maka ojiji, Ibọrọ na-ume iji nyochaa omume mmetụta. Abụkarị nsogbu adịghị ibili, ahụ nke ọrịa anabata nke ọma ọgwụ. Mgbe ụfọdụ, ọ pụrụ hụrụ n'ụdị nfụkasị Jeremaya nke anaphylactic ujo, ọzịza, itching na ihe ọkụ ọkụ. Na ụfọdụ ndị ọrịa, ndị sternum e a mmetụta nke mkpakọ, e nwere ihe mgbu. Nwere ike ugbu fever, belatara ọbara mgbali, osooso nke obi ọnụego. Ị nwere ike nwere nsogbu na-eku ume, dizziness na ọnụnọ acrocyanosis development. N'ihi ovadozu rụrụ extra ibu na obi, machibidoro gafere na-atụ aro dose pụtara "Poliglyukin" ntụziaka ntuziaka. Mbadamba na ọgwụ ndị ọzọ nke onye ọrịa na-ewere, nwere ike ịkpaghasị ihe nke ngwọta.

Analogs reviews

Nnọchi agwọ ọrịa nwere ike "HyperHAES", "Reoglyumanom" ma ọ bụ "Hai-akpali mmasị". Ihe ngwọta na-eji maka otu nzube dị ka "Poliglyukin" na-agụnye "Sterofundin", "Reopoligljukin", "Stabizol".

Dochie "Poliglyukin" ntuziaka maka ojiji ikwe n'ebe ndị ọrịa anaghị dabara a owuwu. N'ihi substitutions ike ga-eji "gelofusin", "Refortan N», «Sorbilakt". A mmetụta yiri nwere ike ịbụ "Albunormom" na "Neorondeksom".

Nyocha na-egosi na ọtụtụ ọgwụ na-enyere na iwepu nsogbu. Ma ebe ọ bụ nke ọ bụla bụ dị iche iche, na ihe ya ochichi nwere ike dị iche iche. Ọtụtụ na-adabere ọrịa na-arịa. People n'ihe ize ndụ nke ghara iji "Poliglyukin" na ha onwe ha, n'ihi na ihe ize ndụ nke na-ezighị ezi ochichi nke ego na mmepe nke mmetụta.

Ọrụ ya ngwọta "Poliglyukin" anamde, ma ọgwụgwọ, nakwa dị ka mmejuputa mgbochi, ọ bụghị irè na emewo ka nsogbu ndị ọzọ, ndị dose nke ọgwụ ga-họọrọ site dọkịta n'otu n'otu. Naanị a ọkachamara nwere ike dọọ ọgwụ ka a nkịtị onye ga-enwe ike n'ụzọ ziri ezi chọpụta chọrọ dose na kwesịrị ekwesị ụzọ nke ochichi nke ọgwụ. Oké doses nke ọgwụ ọjọọ dị ize ndụ obi, n'ihi ya, anaghị iri ihe ize ndụ, na onwe-medicate.