Subleukemic myelosis - na benign variant nke-adịghị ala ala leukemia

Subleukemic myelosis bụ otu n'ime otu ìgwè nke onye na-adịghị ala ala ọrịa kansa ọbara, ebe ihe na-akpata ọrịa na-aghọ a enweghị nchịkwa mgbanwe precursor mkpụrụ ndụ myelocyte. N'out oge na mkpọchị maturation nke hematopoietic mkpụrụ ndụ na ọrịa a usoro mepụtara reactive fibro-sclerotic ọnya na ọkpụkpụ nke ọkpụkpụ na a concomitant mkpakọ nke ụmị ọkpụkpụ na proliferative mgbanwe splin na imeju na. Ọ bụ ya mere subleukemic myelosis kwuru na dị ka myeloproliferative leukemia.

Ihe Kpatara myelofibrosis na variants nke ọrịa

N'ọnọdụ ka ukwuu, ọrịa emee na ndị ọrịa bụ afọ 50 na ndị okenye, ya mere, a ụfọdụ uru mmasị mkpụrụ ndụ ihe nketa malfunction nke nuclear ihe onwunwe azuokokoosisi progenitor sel, autoimmune ọrịa, malitere ịrịa ọrịa. Morphological mkpụrụ-aghọ mieloza ịgbanwe niile atọ izizi hematopoiesis - granulocytic, megakaryocytic na erythroid. Ọ bụ ka ogo ndị a na-anaghị ekwe na-adabere maka ọrịa na prognosis.

N'ọnọdụ ka ukwuu subleukemic myelosis retara kama benign, na e nwere a kpọmkwem mmekọrịta dị n'etiti ndidi afo n'oge mmalite nke ọrịa na prognosis - ndị na-eto onye ọrịa bụ, ike ya myelofibrosis emee. Na ọnụ nkebi nke ọrịa, nke nwere ike ịzụlite mgbe 5-15, na ọbụna afọ 20 mgbe nchọpụta nke mbụ mgbaàmà, ọrịa nwere ike gbawara nsogbu. Mgbe ọrịa na-ewe ke atụmatụ nke nnukwu leukemia: a ọnụ ọgụgụ buru ibu nke fụrụ egosi na elu ọbara. Mgbaàmà nke ndị dị otú ahụ a na mmepe nke ọrịa na-ahụ ọkụ, ihe ịrịba ama nke igbu egbu, ụkọ ọbara na hemorrhagic syndrome. Ọ bụ mgbe ụba splin na imeju na. Na ụfọdụ ndị ọrịa, ikekwe ngwa progression nke ọrịa na n'oge ọdịdị nke syndrome nke ọbara na-agba onye ọrịa ahụ anemizatsiey.

The adakarị picture subleukemic mieloza

Ọtụtụ mgbe ọrịa na-echegbu owụt general adịghị ike, arọ ke afo, nke enwekwu na ije na karịsịa mgbe nri (na ọ bụ n'ihi na a ịrịba abawanye na splin na imeju na). E nwere mkpesa nke isi ọwụwa, ihe mgbu na ọkpụkpụ na ọkpụkpụ azụ. Nnọọ adịkarịghị, na ọnụ na ogbo nke ọrịa, ọrịa ike ịzụlite oké sensory disturbances. The dibịa ga-abụrụ ewepu myelosis funicular - a-enweghị nchịkwa na ọnọdụ nke ụjọ usoro na-adị mgbe ụfọdụ megaloblastic anaemia. Nke a ọnọdụ abụkarị na anaemia, nke pụtara na ọrịa na erighị ihe na vitamin B12 ke idem.

Ọzọkwa, thrombosis mgbe ime, nke na-aghọ ihe na-akpata nke ọnụ ọgụgụ ka elu nke platelet na elu ọbara n'ozuzu, na krovi.Poslednee coagulation ọrịa nwere ike mere site na a morphological obere nwa ọbụna nnọọ a ọnụ ọgụgụ buru ibu nke platelet. Mee elu mee ala, thrombocytosis-eduga ná mmepe nke splenomegaly, ma na splin na-amalite na-gbarie bụghị naanị platelet kamakwa mkpụrụ ndụ ọbara uhie, nke na-akpata mmepe nke anaemia.

The echetakwa mmemme na ọgwụgwọ nhọrọ maka ọrịa

Diagnosis "subleukemic myelosis" kwesịrị itinye bụghị na ndabere nke na-adakarị ọbara ule, na-arụpụta nke sternal mgbapu ọ bụ iliac trepanobiopsy. Mgbanwe ọbara ule bụ n'ụzọ na-abụghị kpọmkwem na naanị na njirimara nke na-abawanye ma ọ bụ ọnụ ọgụgụ nke mkpụrụ ndụ ọbara na-agbanwe ha percentages-apụghị chọpụtara "subleukemic myelosis".

Ọgwụgwọ nke ọrịa na-dabere na steeti ụmị ọkpụkpụ na dị ọkpụkpụ Ọdịdị abnormalities. Mgbe ụfọdụ, ezuru ike chọpụtara nke ndidi, ebe ngwa ngwa na-enwe ọganihu myelofibrosis kwesịrị nhọpụta nke ọgwụ ọjọọ eme ihe.

Na ọnụ ogbo nke ọrịa na ụfọdụ, mkpa na-ata radieshon ọgwụ, oke oru nke na-anara ọgwụ maka nnukwu myeloid leukemia usoro ọgwụgwọ, mwepụ nke splin - ma nke ọ bụla ọ na ọrịa ọgwụgwọ ọrịa ga-ahọpụta a eru hematologist.