"Indomethacin" (mbadamba): ntuziaka maka ojiji, n'ezie na

Otu n'ime ihe ndị na-anọchite anya nke ìgwè nke ndị so ná ndị mgbochi mkpali ọgwụ ọjọọ bụ ọgwụ "Indomethacin" (mbadamba). Ruru ya mgbochi mkpali, analgesic na antipyretic mmetụta nke ya iji maka ọgwụgwọ nke mkpali oria, dochie ihe mgbu, belata ọzịza na iji weghachi nkwonkwo agagharị.

Description of nkwadebe

Isi nọ n'ọrụ mgwa nke ọgwụ bụ indomethacin, nke metụtara indole acetic acid emepụta. Inside nkwakọ agwọ ọrịa "Indomethacin" na-akọwa dị ka mbadamba ndu ọcha na a na-echebe enteric mkpuchi nke na-enye ohere nọ n'ọrụ gị n'ụlọnga na-wepụtara na eriri afọ, na-eleghara afo. Udi nke gburugburu mbadamba, biconvex, n'elu kpuchie a ìhè-agba aja aja shei.

Mbadamba bụ multiple Dosages: 25 mg, 50 mg na 100 mg nke indomethacin. Dị na 10 ma ọ bụ 40 iberibe kwa mkpọ.

All onunu ogwu forms

Ọzọkwa mbadamba, e nwere ụdị ndị ọzọ nke "Indomethacin" nkwadebe maka onu iji, n'ihi na ihe atụ a nyere ntọhapụ Capsule onunu ogwu nke 75 mg. N'ihi rectal ochichi, suppositories na-eji na a dose nke 50 mg. N'èzí ngwa kere ude 5% na 10% na 3% jel.

usoro nke ihe

The agwọ ọrịa bụ a ndị so ná ndị antiinflammatory gị n'ụlọnga systemic edinam, nke nwere antiinflammatory, decongestant, analgesic na antipyretic mmetụta. Mmasị ka ọgwụ ọjọọ, "Indomethacin" (mbadamba) ndu usoro mejupụtara a nkọwa nke ya na ime ndị nọ n'ọrụ mgwa metụtara na a ọnụ ke cyclooxygenase ọrụ nke ụdị 1 na nke 2. N'aka nke ya, nke a enzyme nwere a ntakiri mmetụta arachidonic acid nke na-ebelata ya akakabarede prostaglandin. Ndị bekee ka mbufụt na ihe mgbu.

Indomethacin ngosi antiplatelet mmetụta, mbenata platelet clumping nke mkpụrụ ndụ ọbara. Umi attenuates mgbu na nkwonkwo mgbu a nwayọọ na mobile ala, na-ebelata ụtụtụ isi na ọzịza, enwekwu nso nke ngagharị. Action indomethacin iji na mbenata mbufụt. The kacha mmetụta e nyere ụbọchị nke asaa nke ọgwụgwọ, ọgwụ mbadamba.

na emeso

Dabere na usoro nke-eme ihe, "Indomethacin" mbadamba ntụziaka ntuziaka na-atụ aro na ojiji maka systemic ọgwụgwọ:

• articular syndrome;
• mkpali oria nke nweekwa usoro mere site ọrịa ogbu, psoriatic, ọrịa, ntorobịa ogbu na nkwonkwo, na friji ubu, ankylosing spondylitis, nkwonkwo ọrịa deforming osteitis na uretrookulosinovialnom syndrome;
• degenerative ọrịa nke nweekwa usoro mere site osteochondrosis na radicular syndrome, osteoarthrosis nke nkwonkwo, ma e wezụga ndị hip na intervertebral arthrosis;
• agbasa ọrịa, na-ekpuchi connective anụ ahụ;
• rheumatism;
• suppurative mkpali ọnya nke periarticular na akpa na akwara;
• nnukwu mgbu mgbaàmà ke ala azụ na n'akụkụ ndị ọzọ nke ọkpụkpụ azụ mgbe sciatic neuralgia na ndị ọzọ na akwara, mbufụt nke uru ahụ;
• traumatic mbufụt na adụ anụ ahụ ma ọ bụ na nkwonkwo.

Ọ pụrụ inyere gị aka ịnagide isi ọwụwa, ịhụ nsọ, eze mgbu, ụkwara nta.

Dị ka ihe inyeaka gị n'ụlọnga maka nje na mkpali ọrịa ndị dị ka pharyngitis, tonsillitis, otitis eji agwọ ọrịa "Indomethacin" (mbadamba). Egosi gụnyere ọgwụgwọ nke cystitis, adnexitis, prostatitis.

The ọgwụ bụ irè n'ihi na mwepụ nke febrile syndrome metụtara Hodgkin ọrịa, lymphoma, metastatic etuto ahụ, mgbe bụghị eme paracetamol na acetyl salicylic acid.

Olee na-

"Indomethacin" na nkà mmụta ọgwụ na mbadamba na-ndinọ onye ọrịa na a akpan akpan onunu ogwu dabeere ogo ọrịa. N'ozuzu, ndị okenye na-amalite na-anata a dose nke 25 mg ugboro atọ n'ụbọchị mgbe nri.

Ọ bụrụ na mmetụta nke ọgwụgwọ bụ ezughi oke akpọ abụọ onunu ogwu 50 mg 3 ugboro kwa ụbọchị. Oke allowable dose ekwesịghị gafere 200 mg indomethacin. Mgbe a dị ịrịba ama mma mere site usoro ọgwụ, ọgwụgwọ ga-akwụsị nanị mgbe 4 izu iji gara aga mgbe ọ bụ a belata dose. Ọ bụrụ na ọrịa na-ewere ọgwụ n'ihi na a ogologo oge "Indomethacin" ntụziaka ntuziaka na-atụ aro a dose nke 75 mg nke nọ n'ọrụ mgwa kwa ụbọchị.

ọgwụgwọ nke ụmụ

N'ihi na a na nwa kwa ụbọchị dose gbakọọ amụba 2.5 ma ọ bụ 3 mg na-aru-ya uka, ọ na-e maka 3-4 ugboro. N'ihi na onye ọ bụla afọ otu nyere ojiji nke mbụ kwa ụbọchị dose:

• ụmụ 3 7 afọ ndinọ si 50 mg 75 mg, nke kwekọrọ 2 ma ọ bụ 3 mbadamba;
• ụmụ 7 ruo 12 afọ: si 75 mg 100 mg, nke kwekọrọ na nke 3 ma ọ bụ 4 mbadamba;
• Children isua 12 kenyere site na 100 mg na 125 mg, nke kwekọrọ 4 ma ọ bụ 5 mbadamba.

Ke akpa ụbọchị ole na ole, ị ga-ahụ otú ọgwụ na ahụ nwatakịrị ahụ, ya mere, iji obere dose ọgwụ. Na oge nke ọgwụ na "Indomethacin" (mbadamba) ntụziaka na-apụta, dị ka oge site 6 7 ụbọchị.

atụmatụ n'ikuku

Na nke a, na e nwere a-ekwe omume nke oghom mmetụta na nnata pụtara "Indomethacin" na mbadamba, ọ bụ mma ghara iji maka ọgwụgwọ nke nnukwu rheumatic fever na nwata. Etinyewe n'ime mmiri ara, na-arụsi ọrụ ike mgwa odụk nwa ọbara, enwekwu n'ahụ jaundice na nwa ọhụrụ na-emeri nke imeju mkpụrụ ndụ. Iji zere nke a, kagbuo ara.

Ndị agadi, ọrịa na-arịa ọrịa imeju, akụrụ, digestive tract, dyspeptic mgbaàmà, ọbara mgbali elu, congestive obi odida mgbe ịwa ahụ, ọrịa Parkinson, àkwụkwụ, ime na m na II trimester mgbe ekenye Indomethacin ọgwụgwọ a chọrọ iji nyochaa ọnọdụ nke organism. Ọ dị mkpa ịchịkwa ọrụ nke mfịna akụkụ, ozugbo ọ bụla 7 ụbọchị na-enyocha elu ọbara.

Ọ bụrụ na n'oge gara aga na-asọ ndị na-abụghị steroidal mgbochi mkpali ọgwụ ọjọọ, ọgwụ ọjọọ, "Indomethacin" (mbadamba) họpụtara na oké ikpe.

Anyị adịghị ike ikwu na-eme ihe ize ndụ na-arụ ọrụ na ọgwụgwọ, dị ka ndị na-esogbu ntị ma na psychomotor ọrụ.

Mgbe ị na-apụghị iri

E nwere ọrịa na nke ọgwụ contraindicated "Indomethacin" (mbadamba). Ya iji bụ ekwe omume:

• hypersensitivity ka indomethacin;
• na ọnụnọ nke erosive na ọnyá ọnyá nke digestive usoro na nnukwu-adọ;
• mgbe "aspirin chi atọ n'ime", ji ekweghị ibe nọrọ na acetylsalicylic acid, ọ dịghị òkè polyps na bronchial ụkwara ume ọkụ;
• na hemodyscrasia;
• mgbe akpọ mgbanwe nke imeju na-na akụrụ;
• na a na-egbu oge nke salts na mmiri na-ekwe omume elu edema;
• oké ala ala ọdịda agwa nke myocardium;
• na elu mgbali;
• bronchial ụkwara ume ọkụ;
• na mbufụt nke pancreas;
• na III trimester nke gestation nke nwa;
• ara;
• na ụmụaka na-erubeghị afọ 3.

oghom Jeremaya mere

The ọgwụ "Indomethacin" (mbadamba) nwere ike na-metụtara ndị oghom ihe na-ezighị ezi na-emetụta ọnọdụ nke ahụ mmadụ. N'ihi na nkịtị oghom Jeremaya mere na-agụnye agbọ onunu, anorexia, ihe mgbu ke afo, bloating, afọ ntachi, afọ mgbu.

Na obere okwu, mmetụta nwere ike ime erosive na ọnyá ọnya, na-agba ọbara na perforation nke afo na nsia mgbidi ya; applasticheskoy ma ọ bụ hemolytic anaemia, leukopenia, thrombocytopenia, agranulocytosis, ọkụ ọkụ, ntutu isi ọnwụ, anụ itching, ọdụdọ, angioedema, bronchospasm.

Ihe ịrịba ama nke na-egbu egbu epidermal necrolysis, nnọọ adịkarịghị hụrụ anaphylactic ujo, erythema nodosum.

N'oge ọgwụgwọ nwere ike imebi ọrụ excretory gbasara akụrụ na imeju, nke enwekwu ego nke bilirubin, hepatic transaminases.

Ogologo oge eji ọgwụ ọjọọ, "Indomethacin" (mbadamba) anaghị ewepu oghom Jeremaya mere metụtara na ụra n'ọgba aghara, dizziness, elu neuropathy, isi ọwụwa, n'ahụhụ, ahụ mgbakasị, ike ọgwụgwụ. Ha na-ji clouding nke cornea, conjunctivitis, ikpe impairment, tinnitus, ọbara mgbali elu, edema.

Nyocha

Ọ dị mkpa na-eso niile iwu nke ọgwụ, ewepu niile contraindications.

Na-agwakọta na mbanye nke "Indomethacin" ọgwụ reviews. Mbadamba nwere ihe mmetụta karịa onunu ogwu forms maka mpụga were. Ọzọkwa, ifịk ifịk ọgwụ akọ inhibitors nke cyclo-oxygenase 1 na nke 2, nke na-ahụta ka obere irè na-eme ka a ọnụ ọgụgụ nke ekwesighi Jeremaya mere nke gastro-nsia tract.

Rheumatologists na ha na-agwọ, dọkịta na-awa na-nye iwu ọhụrụ ọgwụ ọjọọ eme ihe si na ìgwè nke oxicams. Ha inhibit cyclooxygenase ụdị 2 naanị, na-enweghị na-emetụta ndị enzyme ụdị 1, nke ana achi achi na mmepụta nke prostaglandins ndị na-echebe digestive usoro. Ọ bụ ya mere oxicams eme obere ojoo afo karịa ọgwụgwọ "Indomethacin" (mbadamba). Ntuziaka na-ezighị ezi nzaghachi agụnye a nkọwa nke mmetụta, ma nke a apụtaghị na ọgwụgwọ ha mkpa ka a gosiri. Ihe niile na-adabere na àgwà nke organism.

Ọtụtụ ndị ọrịa, nke a pụtara na-azọpụta site na azụ mgbu, myalgia, intercostal neuralgia, mgbe ọgwụ ndị ọzọ na-adịghị aka. A mmetụta ọjọọ nta adịghị ibili si ọgwụgwọ nke "Indomethacin" ọgwụ ọjọọ. Nyocha nke mbadamba natara ọrịa rụpụtara ezi. Ọ bụ ezie na ihe ize ndụ bụ mgbe nile, na na dọkịta nwere ike nye iwu ka n'ikuku nke ndị dị otú ahụ a oké njọ ọgwụ.

analogs

Mbadamba na-arụsi ọrụ ike umi Indomethacin na-emepụta site na ọtụtụ ndị mba ọzọ na anụ ụlọ ụlọ ọrụ, dị ka ụlọ ọrụ "Sopharma", "Ludwig Mekle" "Nycomed", "Farmahim", "Berlin Chemie Menarini," "Altfarm". Nani onye ọ bụla ọgwụ ya ahia aha, ya mejupụtara inyeaka mmiri. All na-enyocha otu na-egosi maka ojiji, mmetụta, contraindications.

The kasị ewu ewu na ọgwụ ọjọọ, "Indomethacin Sofarma" (mbadamba). Emepụta a dose nke 50 na 100 mg site "Sofarma" (Bulgaria). Ọ na-ezo aka a na-abụghị steroidal mgbochi mkpali ọgwụ ọjọọ.

Ọzọ ụzọ nke na-erughị mara analogues - ọgwụ "Indomethacin 50 mg nke Berlin-Chemie" na "Indomethacin 100 mg nke Berlin-Chemie". Emepụta abụọ Dosages (50 na 100 mg) site Italian ụlọ ọrụ "Berlin-Chemie Menarini".

Na nkwadebe "Indomethacin" (mbadamba) nwere analogues na Russian mmepụta. Ha bụ ndị dị na iche iche onunu ogwu iche-iche. bụ isi ogbo:

• "Indomethacin-Acre" Chemical-Pharmaceutical Plant JSC "Akrikhin";
• "Indomethacin-Altfarm", LLC "Altfarm";
• "Indomethacin-Biosynthesis", JSC "Biosynthesis";
• "Vero Indomethacin", OJSC "Veropharm".