"Kaffetin Cold": ntụziaka iji mee ihe, mejupụtara, analogues

Kedu ọgwụ bụ "Kaffetin Cold"? A ga-atụle ihe mejupụtara na njirimara nke ọgwụ a n'okpuru. Ọzọkwa, anyị ga-agwa gị banyere otu esi aṅụ ọgwụ a na n'okpuru ọrịa ndị ọ na-ede.

Ụdị, nkwakọ ngwaahịa, mejupụtara

Aṅụ ọgwụ "Kaffetin Cold" na-ere ahịa n'ụdị mbadamba nkume oblong na biconcave (nke nwere ihe ize ndụ na otu akụkụ), kpuchie ya na-acha anụnụ anụnụ. A na-etinye ha na ọnya a na-ahụ anya, nke na-agụnye ihe nkiri aluminum na ihe nkiri okpukpu atọ, nke dị na kaadiboodu.

Kedu ihe ọgwụ dị ka "Kaffetin Cold" nwere? Ihe mejupụtara ọgwụ a bụ:

• Hydrobromide dextromethorphan (15 mg);
• Pseudoephedrine hydrochloride (30 mg);
• Ascorbic acid (60-62 mg) n'ụdị granulate nke nwere 97% nke vitamin C na 3% nke hydroxypropylmethylcellulose;
• paracetamol (500-555 mg) n'ụdị nsogbu dị iche iche esịnede 90% nke umi, nakwa dị ka inyeaka mmiri ka prozhelatinizirovanogo starch, stearic acid na povidone.

Ọ kwesịkwara kwuru na "Kaffetin Nzuzo" dị ka ndị ọzọ Efrata na-agụnye magnesium stearate, silica colloid, microcellulose, croscarmellose sodium na talc.

Film mkpuchi nke agwọ ọrịa ka nke-acha anụnụ anụnụ e ji esiji ákwà, macrogol, titanium dioxide, polyvinyl mmanya na talc.

Ọgwụ ọgwụ na ọgwụ

Kedu ihe bụ àgwà maka mbadamba "Kaffetin Cold"? Ntuziaka ahụ na-ekwu na onye ọrụ a nwere ike igosipụta ụdị analgesic na antitussive.

Usoro nke ime ọgwụ a bụ n'ihi ọnụnọ ya n'ime ihe ndị dị n'elu. Ka anyị tụlee atụmatụ ha ugbu a:

• Paracetamol na-eme n'ahụ anesthetizing na antipyretic. Nke a nwere ike igbochi COX na usoro nhụjuanya dị n'etiti. Nke a na-eme site na mmetụta ziri ezi na ebe mgbu na thermoregulation.

Ihe dị iche iche nke ihe a sitere na NSAID bụ enweghị njigide nke mgbochi mkpali. Paracetamol anaghị eme ka mịcosa nke akụkụ eriri afọ, ma ọ bụ na ọ na-emetụta nsị metabolism nnu, ebe ọ bụ na ọ nweghị mmetụta na-adịghị mma na njikọ nke prostaglandins n'ime anụ ahụ.

• Kedu ihe ọzọ dị ịrịba ama gbasara ọgwụ "Kaffetin Cold"? Mwepu nke pseudoephedrine nwere ike itinye mmetụta dị nkpa n'ahụ arịa ndị dị na mucosa nke pharynx na oghere ntụrụndụ. Nakwa, nke a na-ebelata ihe edema, si otú ahụ na-ebelata secretion na nasopharynx ma na-enye ume iku ume.
• Ascorbic acid, nke dị na ọgwụ a, na-enyere aka iweghachi vitamin C, nke a na-ahụkarị n'oge oyi.
• Dextromethorphan nwere mmetụta na etiti ụkwara. Ọ na-ebelata oke ụkwara ụkwara, nke ejikọtara na mgbakasị nke mucous nasopharynx maka oyi.

Ihe nketa kinetic

Kedu ka mmiri ọgwụ "Kaffetin Cold" si eme? Nzaghachi ndị ọkachamara na-egosi na absorption nke ọtụtụ paracetamol na-apụta n'ime eriri afọ. N'otu oge ahụ, a na-ahụ ọnọdụ kasị elu n'ime plasma ọbara n'ime 30-90 nkeji mgbe ọ gwụchara ọnụ.

Metabolism nke ihe dị na ajụjụ (ihe dịka 90-95%) na-eme n'ime imeju. N'ihi ya, a na-emepụta ihe mgbatị na-adịghị arụ ọrụ (n'ihi mmeghachi omume mmeri na glucuronic acid na sulfates). Ha nwere ike ịnwe mmetụta na-egbochi usoro usoro mmezigharị imeju, nakwa nke kpaliri ọnwụ nke mkpụrụ ndụ ha.

Ọkara ndụ nke akụrụngwa a sitere na ahụ mmadụ bụ awa 1-4. Paracetamol na ndị metabolites na-egbochi akụrụ. Na nká, enwere ike ibelata nkwụsị ịṅụ ọgwụ ọjọọ, yana mmụba na ọkara ndụ.

Mgbe dextromethorphan batara n'ime ahụ mmadụ, ọ na-etinye ya n'ime ọbara ozugbo. A na-ahụ ihe kachasị mma nke mmewere a na plasma na minit 130 mgbe o were mbadamba nkume ahụ. Ihe a na-emeju na imeju. A na-ejikọta ya na ndị na-amịkọrọ ya na urine.

Pseudoephedrine na-etinyekwa ngwa ngwa n'ime usoro mgbasa ozi mgbe ọ na-achịkwa ọnụ. A na-enweta ihe kachasị elu nke ihe a na plasma n'ihe dị ka awa 2. Ọkara ndụ nke pseudoephedrine bụ ihe dị ka awa isii. Ọ na-emeju na imeju (nke dị na ya), na-eme ka e guzobe ihe mgbapụta nke a na-esite n'anụ ahụ mejupụta urine.

Maka ascorbic acid, a na-etinyekwa ya na tract digestive ma na-ekesa ngwa ngwa na anụ ahụ niile. Akuku a bu ihe eji eme ka abuo si dihydroxyascorbic acid. N'otu oge ahụ, akụkụ ụfọdụ nke vitamin C, nke batara n'ime ahụ, na-etinye aka n'ime ihe a na-akpọ ascorbate-2-sulfate.

A na-ewepụ ihe a na ahụmịnụ.

Ntu

A na - eji ọgwụ "Kaffetin Cold" mee ihe maka nrịbama nke ọrịa influenza na oyi, gụnyere mgbe enwere ihe mgbaàmà dị otú ahụ dị ka isi ọwụwa, ụkwara akọrọ, mgbu ahụ mgbu, akpịrị akpịrị, imi imi, ọkụ, nchịkọta ntụrụndụ na nchịkọta aka .

Contraindications

A pụghị iji ọgwụ ọjọọ "Kaffetin Cold" nye ndị ọrịa n'ọnọdụ ọnọdụ ndị a:

• Ime ime;
• Mmetụta nke ọgwụ;
• Enweghi ike nke glucose-6-phosphate dehydrogenase;
• Ọrịa mgbali elu, ọrịa akwara ọbara, angina pectoris;
• Mmebi ukwu na-arụ ọrụ akụrụ na imeju, ịba ọcha n'anya;
• Ugboro oge iji antidepressants, monoamine oxidase inhibitors na ọgwụ ọjọọ eme ihe na-eji na antiparkinsonian ọgwụgwọ;
• Ọkụ;
• Afọ ruo afọ 12.

Kpachara anya, a na-atụ aro ọgwụ a maka:

• Arrhythmias;
• Hyperbilirubinemia nke dị ọcha;
• Hyperthyroidism;
• Ọrịa ịba ọcha n'anya;
• Hyperplasia nke prostate gland;
• Alcoholism;
• Ọrịa shuga shuga;
• Imebi ọrịa nje nke ọrịa na-adịghị ala ala;
• Ọrịa asthma;
• Ike ọgwụgwụ.

Ọgwụ "Kaffetin Cold": ntụziaka maka ojiji

A na-ezu ọgwụ a maka nchịkwa ọnụ.

Ọgwụgwọ nke ọgwụ maka ndị okenye na ndị nọ n'afọ iri na ụma site na afọ iri abụọ bụ 1 mbadamba nkume ugboro anọ n'ụbọchị. N'otu oge, a naghị ahapụ ihe karịrị 2 mbadamba.

Oge nkeji n'etiti iji ọgwụ eme ihe ekwesịghị ịbụ ihe na-erughị awa anọ. N'okwu a, usoro ọgwụgwọ kwa ụbọchị nke ọgwụ ekwesịghị ịfe 8 mbadamba.

Ọ bụrụ na a hụrụ ogo ahụ dị elu karịa ụbọchị 3 site na mmalite nke ọgwụgwọ, ụkwara akọrọ adịghị agafe maka ụbọchị 5, mgbe ahụ rịọ enyemaka enyemaka ahụ ozugbo.

Ihe a na-eme n'oge ụfọdụ

Mmeghachi omume na-adịghị mma mgbe ịṅụ ọgwụ na ajụjụ nwere ike igosipụta onwe ha n'ụzọ dịgasị iche iche, site na akụkụ niile nke anụ ahụ:

• Nausea, ọnụ ọkụ, nsogbu mgbu;
• Ụjọ, mgbakasị, mgbakasị, nkwụsị;
• Ndị na-arịa ọrịa ala n'ụdị akpụkpọ anụ, anụ ọkụ ọkụ, angioedema, hives;
• Ọbara mgbali elu, mmepe nke tachycardia;
• Anmia, thrombocytopenia, agranulocytosis, pancytopenia;
• nephrotoxic mmetụta, nke na-egosipụta gbasara akụrụ colic, mmepe nke papillary necrosis ma ọ bụ interstitial nephritis.

Ndozi ọgwụ

Mgbe ị na-aṅụ ọgwụ dị elu, onye ọrịa ahụ nwere ike ịnweta ọgbụgbọ, na-etigharị na ntị na mgbu na afọ. Ọzọkwa, mgbe usoro ọgwụgwọ ahụ gafeworo, akpụkpọ ahụ onye ahụ na-acha ọcha, njedebe ya na-abawanye ma obi ya na-abawanye elu.

Ihe ndị a kọwara na-achọ ime ngwa ngwa nke afọ. Ọzọkwa, a na-enye onye ọrịa otu mkpụrụedemede nke carbon kwekọrọ na ịdị arọ nke onye ọrịa ahụ. Ọ bụrụ na achọrọ, mgbe ahụ, a na-eme ọgwụgwọ symptomatic.

Mmekọrịta

Iji paracetamol mee ihe n'ọtụtụ dosịtị na-eme ka mmetụta nke anticoagulants dịkwuo.

Iji ọgwụ ọjọọ eme ihe na-inducers nke microsomal ọxịdashọn (e.g., "Phenytoin", ethanol, barbiturates, "Rifampicin", "phenylbutazone", tricyclic antidepressants), na hepatotoxic mmadụ budata enwekwu ndị guzobere nke nọ n'ọrụ hydroxylated metabolic ngwaahịa nke paracetamol, nke enwekwu likelihood nke oké igbu egbu Development , Na-agụnye mgbe ị na-ewere obere ọgwụ ọgwụ.

Ogologo oge ojiji nke nchịkwa na-ebelata irè paracetamol.

Ngwakọta nke paracetamol na salicylates na-eme ka ohere nke ịrịa ọrịa ma ọ bụ akụrụ akwara na-amụba.

Ruo ogologo oge iji NSAID na paracetamol akwalite omume analgesic nephropathy, gbasara akụrụ papillary necrosis na dị nso na njedebe-ogbo gbasara akụrụ odida.

Ojiji nke "mmepu" na-eduga ná mmetụta ọgwụ ọjọọ nke ọgwụ ọjọọ.

Ntughari uzo nke pseudoephedrin na ndi ozo n'enye aka na ha puru itinye aka na nsogbu nke ihe ojoo, ma nweekwa ihe omuma. Nchikota nke akuko a na ndi ozo na-ebute oxidase monoamine na-eduga n'inwe nsogbu nsogbu hypertensive. N'ebe a, a na-ekwe ka iji ọgwụ ahụ eme ihe na-ekweghị tupu ụbọchị iri anọ na anọ mgbe a kwụsịrị ịchịkwa ndị na-egbochi monoamine oxidase.

N'iji ya tụnyere "Propranolol" na-eme ka mmetụta nrụpụta ahụ dịkwuo, nke na-apụta ịbụ pseudoephedrine. Tụkwasị na nke ahụ, site n'iji nke ikpeazụ eme ihe, mmetụta dị egwu nke ndị ọrụ dịka "Methyldopa", "Reserpine", "Mekamilamin" na ihe ndị yiri ya nwere ike ibelata.

Ozi puru iche

Ugbu a ị maara ihe ọgwụ dị ka "Kaffetin Cold" bụ.

A na-ahụkarị na Pervitine. Ọ bụ psychostimulant ma na-eme ka mmadụ bụrụ onye dị elu, bụ nke a na-ekwu na ọ bụ ihe akọrọ. Ụfọdụ ndị na-agbalị iwepu mpaghara a site na ọgwụ "Kaffetin Cold". A na-emetọ ọgwụ ọjọọ n'ọtụtụ ụzọ. Ọfọn ya na-ebute ụbụrụ na n'otu oge ahụ na-emebi usoro niile na akụkụ mmadụ.

Na usoro ọgwụgwọ, ọgwụ ahụ a na-atụle ga-eleba anya na ọnọdụ ahụ nke imeju onye ọrịa ahụ, yana ndị na-egosi ọbara ọbara.

N'oge ọgwụgwọ dum, a na-egbochi onye ahụ ịṅụ ihe ọṅụṅụ na-aba n'anya, n'ihi na nke a nwere ike iduga mmetụta ọgwụ ọjọọ nke ọgwụ. Otu ihe a na-emetụta ngwaahịa na ngwaahịa caffeine.

Ọgwụ a na-atụle na-emetụta mmetụta nke onye ọrịa ahụ iji jikwaa ịkwaga ma na-eme ihe ọ bụla ọzọ nke chọrọ ka ụba elebara anya.

Ọgwụ ọjọọ "Kaffetin Cold": hapụ ụlọ ọgwụ

N'ihi eziokwu ahụ bụ na a na-ejikarị ọgwụ a eme ihe dịka ọgwụ ọgwụ ọjọọ, a na-ahapụ ya naanị mgbe e gosipụtara dọkịta ahụ. Site n'ụzọ, ọ na-esi ike ịchọta ọgwụ dị otú ahụ na ụlọ ọgwụ. A na-enyekarị ya mgbe edechara ya.

Ọgwụ ndị yiri ya

E nwere ọtụtụ ụzọ a pụrụ isi jiri ọgwụ a mee ihe. Otu n'ime ndị kasị ewu ewu bụ ihe ndị a: Amitsitron Forte, Antigrippin, Bol-Run Premium, Vokasept, Grippo, Grippold-N, Gripotsitron Forte, Gripflu, Dolaren, Cold-N, Coldrex, Coldfreak, Lemsp Lemon, Novalgin, Panadol Extra, Rinza, Tamipul, Pharmacitron na ndị ọzọ.