"Klivas": ntuziaka maka ojiji, n'ezie na

Na-abawanye na cholesterol bụ nchegbu bụ isi, karịsịa ma ọ bụrụ na onye ahụ ọ na-ata ahụhụ site ọrịa obi. Drug "Klivas" ntụziaka ntuziaka nke na-akọwa n'ụzọ zuru ezu na iwu nke na-ewere ọgwụ na-na-enyere aka belata cholesterol nkịtị na-akawanye ọrịa na-arịa na-eme n'ọdịnihu.

Structure na mejupụtara

Nkwadebe "Klivas" (ntuziaka maka ojiji mmasị ka ọgwụ ọjọọ) dị na mbadamba ntekwasa na a na-acha ọcha shei. Mkpụrụ ọgwụ nchọ na aluminum ọnya nke iri. The katọn nwere ike ịbụ otu ma ọ bụ atọ blisters.

Mbadamba dị na 10 mg na 20 mg. N'ọrụ umi eme rosuvastatin.

pharmacology

Rosuvastatin akọ Nhọrọ inhibitors nke HMG-CoA reductase enzyme. Atọghata HMG-CoA ka mevalonate, predmestnik cholesterol. Isi ebe ọrụ a na-ewere rosuvastatin imeju. Ọ bụ ebe a na e nwere ihe mkpakọrịta nke cholesterol na catabolism nke LDL.

Therapeutic edinam ịrịba n'izu mbụ nke ọgwụ ochichi, mgbe 14 ụbọchị, a nti utịp bụ hà 90%. Onye kasị ukwuu mmetụta pụrụ enweta site n'ịkpa a n'aka nọgidere ofụri ọnwa.

Ịnata rosuvastatin enye arụpụta ihe kasị mma na ọgwụgwọ nke ọrịa na hypercholesterolemia, hypertriglyceridemia ma ọ bụ na-enweghị. Mmetụta emee n'agbanyeghị okike, afọ na agbụrụ. A mma N'ihi na ndị mmadụ na-arịa ọrịa shuga na-ata ahụhụ site ezinụlọ hypercholesterolemia.

Additivity a hụrụ na Nchikota na fenofibrate n'iru TG na nicotinic acid na ọdịnaya nke HDL cholesterol.

na-agba akaebe

Eji "Klivas" nkwadebe (ntuziaka maka ojiji kọrọ contraindications a ga-atụle tupu iji ọgwụ ọjọọ) n'ihi na ndị okenye na-egosi na hypercholesterolemia. Kenye pụtara na mbụ ogbo nke hypercholesterolemia na weere dyslipidemia ụdị. Jiri mbadamba ka adjunctive ọgwụ nri dị ka ekwukwa n'akwụkwọ ọgwụ, na-azụ ahụ na ibu Mbelata ezughị.

Prescribers na homozygous ezinụlọ hypercholesterolemia. Ha ịgbakwunye na ihe oriri na-eji ndị ọzọ lipid-ẹsụhọde ọgwụ ọjọọ. The ọgwụ atara na mgbe ngwa nke n'elu ụzọ bụ ekwe omume.

Nwere ike ikwu ọgwụ maka ọrịa na obi ọgba aghara, na a puru nke omume nke atherosclerotic ọrịa obi agwa. Ndị a ihe ize ndụ ihe na-agụnye ọbara mgbali elu, okenye afọ, ala cholesterol ọnụego, mụbara C-reactive protein, a pụrụ ịrịa mmepe nke ịrịa ọrịa obi na ise siga.

The ọgwụ a na-eji na ọgwụgwọ nke atherosclerosis. Ke idaha emi, ọ na slows ala progression nke ọrịa na ọrịa a na-kenyere lipid-ẹsụhọde ọgwụ.
"Klivas" nwere ike iji na-emeso ụmụ noo n'etiti iri na iri na asa. The ụmụ nwoke kwesịrị ogbo II ọrịa, na n'elu on a ọnụ ọgụgụ nke Tener, ụmụ agbọghọ nwere ike na-ọgwụ dịghị tupu otu afọ mgbe menarche. Ebe a ọgwụ gosiri maka ọgwụgwọ nke isi hypercholesterolemia, nakwa dị ka na nchoputa nke "mbuaha dyslipidemia" ma ọ bụrụ na ọrịa ahụ mepụtara n'ihi heterozygous ezinụlọ hypercholesterolemia. The ọgwụ na-eji na Nchikota na nri na physiotherapy, tinyere ndị na-abụghị ọgwụ usoro ọgwụgwọ.

contraindications

Mbadamba "Klivas" (ntuziaka maka ojiji nke ọgwụ tupu ojiji ga-nlezianya mụọ), n'agbanyeghị a elu ọgwụgwọ mmetụta apụghị-eji n'ihi na elu uche na nọ n'ọrụ gị n'ụlọnga nkwadebe - rosuvastatin, nakwa dị ka ọ bụla inyeaka components na ha mejupụtara. Iwu ruo oriri na-imeju ọrịa na ha nọ n'ọrụ na-adọ, oké akụrụ malfunction na myopathy. Ekwela ikpokọta ọgwụ na cyclosporine. Dọkịta adịghị idepụta ọgwụ, ọ bụrụ na nwaanyị dị ime ma ọ bụ ara. Ladies toruworo ịmụ nwa na iji ọgwụ ọjọọ eme na-atụ aro iji ezigbo igbochi afọ.

The onunu ogwu nke 40 mg ekwesịghị kenyere ndị na a pụrụ ịrịa ndị progression nke myopathy / rhabdomyolysis. Ndị a gụnyere ọrịa nke gbasara akụrụ usoro nke na-agafeghị oke ogo, hypothyroidism, butere n'aka muscular ọrịa na miotoksichnost akụkọ ihe mere eme, mmasị nke na-aba n'anya. Ejila a dose n'ọnọdụ ndị na-amụba na ọkwa nke nọ n'ọrụ mgwa ke iyịp. Ejila a ego nke ọgwụ ọzọ nke Mongoloid agbụrụ.

"Klivas": ntuziaka maka ojiji

20 mg (10 mg) nke nọ n'ọrụ umi rosuvastatin dị onye ọ bụla mbadamba. Mkpụrụ ọgwụ ndị mmanya na-egbu, n'agbanyeghị oge nke ụbọchị na-eri. Ha apụghị ga-ata ata na a ga-elo dum na ọtụtụ mmiri.

Agwọ maka hypercholesterolemia na-amalite na obere doses nke 5-10 mg ugboro kwa ụbọchị. Dị otú ahụ ego adabara ndị na-adịghị mbụ na-eji statins na ndị ọrịa na mbụ gbalịrị HMG-CoA reductase. Mgbe ịgbakọ mbụ dose dabeere na eke larịị nke cholesterol n'ime ọbara na a ga-ekwe omume n'ihe ize ndụ nke ọrịa obi, na likelihood nke mmetụta. Dịkwuo dose nke ọgwụ nwere ike izu anọ.

Ịtụle na na a kwa ụbọchị dose nke 40 mg ịzụlite mmetụta ugboro ugboro karịa na ojiji nke nta quantities nkwadebe, ịkpọlite ndị dose 40 mg ga naanị ọrịa na-ata ahụhụ si na oké hypercholesterolemia ogbo na-enwe a elu n'ihe ize ndụ nke ọrịa obi. Ọ bụrụ na ndị chọrọ N'ihi na agaghị nwetara na a dose nke 20 mg, mgbe na-amụba na onunu ogwu 40 mg nke onye ọrịa ga-esịn idem ese enyịn a dọkịta.

N'ihi mgbochi nke obi odida pụtara ụbọchị dose bụ 20 mg. N'ihi na ndị mmadụ tọrọ afọ 70 nke kwa ụbọchị ọnụego ekwesịghị gafere 5 mg.

Ụmụaka na-eto eto na heterozygous ezinụlọ hypercholesterolaemia, a ọgwụ kenyere 5-20 mg ugboro kwa ụbọchị, na-dose kwesịrị titrated.

N'ihi na ndị mmadụ na-agafeghị oke gbasara akụrụ ọrụ mbụ dose bụ 5 ml. The nkwadebe na-ego nke 40 mg contraindicated. Ị nwere ike iji "Klivans" (ntuziaka na-akọwa na ihe nkowa ọnọdụ) ọrịa na oké ọrịa nke gbasara akụrụ usoro.

Mbadamba na-contraindicated mmadụ na-ata ahụhụ site na gbasara akụrụ ọrịa ike. Na ọrịa na oké gbasara akụrụ ọrịa usoro e nwere ike ịbụ onye na-abawanye nke rosuvastatin. Na nke a na ọgwụgwọ dose adịghị gafere 10 mg.

Na Mongoloid agbụrụ isi onye na-abawanye na systemic ikpughe rosuvastatin, otú amalite ọgwụgwọ na 5 mg. Therapeutic dose of 40 mg nditịm contraindicated. The kacha kwa ụbọchị oriri - 20 mg.

Ndị mmadụ na-na-ewekarị nwayọọ myopathy, amalite usoro ọgwụgwọ na 5 mg na 40 mg dose nke ọtụtụ n'ime ha na-aju. Karịa ọnụ ọgụgụ nke natara ihe onwunwe ke ụbọchị - 20 mg.

mmetụta

Ọtụtụ ndị ọrịa nwere mmasị ma na-adịghị mma mmeghachi omume "Klivas" organism akpata (mbadamba)? Guide na-akọwa n'ụzọ zuru ezu na ihe niile atụmatụ nke na ojiji nke ọgwụ. Dị ka nchịkọta, ọ kọrọ naanị nwayọọ na-akwụsị akwụsị mmetụta. E nwere ọgbụgbọ, dizziness, myalgia, afọ ntachi, afọ ọsịsa, asthenia (na elu doses), ụkwara, myopathy.

Site n'oge ruo n'oge ọrịa nwere itching, aṅụ, anụ ọkụ ọkụ. Ahụla ikpe nke proteinuria na tubular malite. Protein bụ mgbanwe mmamịrị, nke utịp ke na-abawanye na imeju transaminases. Kọrọ nwayọọ ịda mbà n'obi, ehighị ụra nke ọma, na-arọ nrọ na-ehi ụra na-enwe nsogbu, mmekọahụ dysfunction.

N'oge ọgwụgwọ nke ụmụ mmadụ ichegbu na mmeghachi omume, ndị na-akpata nke jere ozi dị ka a pụrụ iche uche ọgwụ (mgbe ụfọdụ mere angioneurotic edema). Ụfọdụ ọrịa chọpụtara pancreatitis na myopathy (gụnyere myositis). rhabdomyolysis e ofu, ya ugboro ole na ụfọdụ adabere na dose-abawanye.

Oké adịkarịghị polyneuropathy, ebe nchekwa ọnwụ. jaundice na ịba ọcha n'anya e achọpụtara n'ọnọdụ ole na ole. Mgbe ụfọdụ, m hụrụ Stevens - Johnson syndrome, arthralgia, haematuria, edema.

ovadozu

Ọ na-ike na-atụ aro ime na-atụ aro usoro onunu ogwu Erere "Klivas" ntụziaka. Nyocha-ekwu na ọ bụ irè na nnọọ oké ọnụ price maka ọgwụ. Ọ na-enye ogologo na-adịgide adịgide na-arụpụta. N'ihi na onye ọ bụla ndidi na onye dose a gbakọọ, na ọ bụrụ na ọ na-adịghị ime, o nwere ike ime ka ihe ovadozu. Special ọgwụgwọ na-adịghị nyere. The ọgwụ na-ekenịmde dị ka ihe mgbaàmà ịda. N'oge a, i kwesịrị nlezianya nyochaa imeju ọrụ na CK etoju. Hemodialysis adịghị enye chọrọ mmetụta.

nchekwa ọnọdụ

Medicine "Klivas" (ọrụ na ọgwụgwọ na a ọgwụ ga-hụrụ) kwesịrị echekwara ke akpasarade ngwugwu na okpomọkụ adịghị nnọọ +25 Celsius C, nke iru nke ụmụ. Ọgwụ rue n'ime afọ abụọ na ụbọchị nke rụpụta.

Analogs "Klivasa"

Drug "Klivas" abụghị ọsọ ke Russia, otú ahụ, n'agbanyeghị na ya arụmọrụ, ndị mmadụ nwere anya n'ihi na a nnọchi.

Site analogues enwe a mejupụtara nke otu ifịk umi (rosuvastatin), na-agụnye ndị na-esonụ ka ọgwụgwọ: 'Crestor "," Merten "," Redistatin "," Roviks "," bilie "," Rozart "," Rozvator "" Rosuvastatin Krka "" Rosuvastatin Teva "," Rozukard "," Rozulip "," Rozusta "," Romestin "," Rosukor "," Rofast "," Fastrong ".

Ndị a na ndị ọzọ na ọgwụ ọjọọ nwere ike kpamkpam-eji dochie "Klivas". Ihe dị iche n'etiti ha bụ price, na emeputa na ịta nke nọ n'ọrụ mgwa.

nleba

Ọ dọrọ aka ná ntị na ọ dị mkpa ime na niile dọkịta ntụziaka mgbe na-ewere mbadamba "Klivas" ntụziaka ntuziaka. Nyocha banyere nke a ọgwụ ọjọọ dị mma. Ọrịa na-ekwu na n'oge nke mbụ izu abụọ nke ọgwụ na-akawanye onye ọrịa na-eduga ná nkịtị cholesterol. Ọ bụ ọnụ ala, na ọrịa na-ewere ya, obi ụtọ na N'ihi.

Ọ dọrọ aka ná ntị na ọ dị mkpa ime na niile dọkịta ntụziaka mgbe na-ewere "Klivas" mbadamba, ntụziaka ntuziaka. Nyocha banyere nke a ọgwụ ọjọọ dị mma. Ọrịa na-ekwu na n'oge nke mbụ izu abụọ nke ọgwụ na-akawanye onye ọrịa na-eduga ná nkịtị cholesterol. Ọ ga-abụ ọnụ ala ọgwụ, na ndị ọrịa na-ewere ya, obi ụtọ na N'ihi.

N'agbanyeghị nke a, ụfọdụ ndị mmadụ na-aṅụ nnukwu doses, kwuru na, na mmetụta. Ha nsogbu ụra, na-arọ nrọ nsogbu n'obi, e nwere a ịda mbà n'obi. Otú ọ dị, ndị dọkịta na-gwara ọ bụghị iji kwụsị omume na-aṅụ ihe ọṅụṅụ ọgwụgwọ maka dịkarịa ala otu ọnwa. Mgbe N'ezie ọrịa ẹkenọde normalized cholesterol, na mmetụta okụrede.