Lipid-ẹsụhọde ọgwụ "Rosuvastatin": ntuziaka maka ojiji

Medicine "Rosuvastatin" ntụziaka ntuziaka na-akọwa dị ka hypolipidemic ọgwụ nke statins. The ọrụ nke a nhọrọ n'aka bụ asọmpi mgbochi nke HMG-CoA reductase. The ojiji nke a nkwadebe "Rosuvastatin" (ntuziaka maka ojiji ọ na-akwado) ọtụtụ ugboro ụba LDL catabolism, mụbara ọnụego hepatic LDL anabata na ego nke VLDL belata. Ma ndị na-pharmacokinetic Njirimara nke lipid-ẹsụhọde ọgwụ ọjọọ, akpọ ọgwụgwọ mmetụta nke ya n'ikuku hụrụ ụbọchị asaa mgbe mmalite nke usoro ọgwụgwọ, na-eru ya kacha mma n'ihi na izu anọ.

Were Erere "Rosuvastatin" emeputa na-atụ aro na ndị mmadụ na-ata ahụhụ site na mbuaha ụdị hypercholesterolemia (pịnye IIb) hypercholesterolaemia ma ọ bụ IIa (gụnyere heterozygous) dị ka ihe adjunct ka nri.

N'ihi ya kasị elu arụmọrụ hypolipidemic ifịk ọgwụ bụ na ikpe mgbe ndị ọzọ ọgwụgwọ ụzọ (mmega ahụ, mbelata nke ahu aro) adịghị eduga inweta nke a kwesịrị ekwesị ọgwụgwọ N'ihi. Ọzọkwa, iji nhọrọ gị n'ụlọnga "Rosuvastatin" ntụziaka ntuziaka na-atụ aro ka ihe inyeaka ọgwụ n'oge ọgwụ homozygous hypercholesterolemia ezinụlọ ụdị.

Kenye ndị a mbadamba na-machibidoro bụrụ na nke a ọrịa nke oké imeju ọrịa, myopathy ma ọ bụ ọrịa na-egosipụta n'ụzọ na akụrụ. N'oge ime, na-ekwesịghị lipid-ẹsụhọde ọgwụ ọjọọ "Rosuvastatin." The na nkà mmụta ọgwụ na-contraindicated na lactation oge. Ọzọkwa, ọ na-adịghị na-atụ aro ka ndị a mbadamba concurrently na cyclosporine ma ọ bụ hypersensitivity ha mmiri. Persons ndị na-imezu afọ iri na asatọ, na ọ dịghị mkpa ka ọ họpụta a nhọrọ gị n'ụlọnga "Rosuvastatin." Ntuziaka maka ojiji na-abụghị gwara ya na ikpe nke na-aba n'anya na nduzi ike gbasara akụrụ odida ma ọ bụ imeju ọrịa.

Na oke-elekọta iji lipid-ẹsụhọde ọgwụ ọjọọ kwesịrị ịbụ ndị mmadụ na-ata ahụhụ electrolyte, endocrine na metabolic ọrịa, hypothyroidism ma ọ bụ hypotension. Na sepsis, agụụ Akwụkwụ na-adọ, proteinuria, isi trauma na ịwa ahụ adọ nwekwara ga kwụsị ịṅụ ọgwụ ọjọọ, "Rosuvastatin." Ke adianade do, ikwu contraindications bụ butere n'aka muscular ọrịa na afọ tọrọ iri isii na ise.

Ná mmechi, ọ ga-kwuru banyere omume oghom Jeremaya mere, omume nke nwere ike triggered site n'ikuku pụtara "Rosuvastatin." Ka ihe atụ, ọtụtụ ndị ọrịa mkpesa nke abdominal mgbu, afọ ntachi, dizziness na ọgbụgbọ. Ke adianade do, e nwere obere ihe ize ndụ nke myopathy, proteinuria, asthenia , na myalgia.