Sekọndrị immunodeficiency

Secondary immunodeficiency - a mebiri nke dịghịzi usoro na-amalite na postnatal oge. Ọ nwekwara ike ime na ndị okenye.

E nwere atọ ụdị nke abụọ immunodeficiencies: rata, enwetara, n'amaghi ama.

Otu atụ dị ịrịba ama bụ enwetara ụdị AIDS. Isi ọgụ, na nke a, n'ihi na mmetụta nke mmadụ immunodeficiency virus.

Rata ụdị emee n'okpuru nduzi nke kpọmkwem na-akpata, nke na-edu ya na omume. Ndị a gụnyere ndị X-ray radieshon, corticosteroids, cytostatic ọgwụ, usiakidem, ihe ọjọọ, mkpọchị ọgụ, nke na-amalite nke abụọ na isi ọrịa (akụrụ, ọrịa imeju, ọrịa shuga, cancer).

Ọ bụrụ na ọ dịghị ihe doro anya kpatara na-akpata mebiri reactivity sekọndrị immunodeficiency a na-akpọ n'amaghi. Clinically ya na-egosipụta ugboro ugboro ntighari na-efe efe nke mkpali uduot ke broncho-akpa ume ngwa, paranasal sinuses, urogenital, eriri afọ tract, anya, anụ, adụ anụ ahụ, nke na-kpatara opportunistic pathogens. Ya mere, na-egbu oge, adịghị ala ala, mgbe mgbe relapsing mkpali Filiks nke dị iche iche orunótu okenye chọpụta adakarị ngosipụta nke abụọ immunodeficiency ekwu.

The kasị ụdị nke ala data bụ n'amaghi. Primary immunodeficiency ji a abụọ na ọ dabeere na ebum pụta ụwa dịghịzi usoro ọrịa.

Mgbe ọrịa na-nsogbu n'obi ọrụ nke niile usoro nkeji: T, B cell, phagocytic, zuo ezu. Iji mata ọrịa na nkwarụ na-ekewa atọ dị iche iche:

- kwuo ịjụ ọgụ, nke na-achọkwa na-mgbanwe nke ya kwa;

- na e nwere nanị ihe ịrịba ama nke dịghịzi erughi na-adịghị esonyere site na a mgbanwe nke ya kwa;

- E nwere mgbanwe ndị na-parameters na-adịghị esonyere site na ihe ịrịba ama nke dịghịzi erughi.

Secondary immunodeficiency achọpụtara site laabu ule: mkpebi siri ike nke dịghịzi status (nọmba nke leukocytes na-nyochaworo, subpopulations nke B na T lymphocytes, etoju nke immunoglobulin M, G, A, phagocytosis). Ọzọ ụzọ na-agụnye njirimara nke comorbidities na ya n'ihu ọgwụgwọ. Dị ka akọwapụtara site na-abụghị kpọmkwem egosi nke nnukwu-adọ, interferon ọnọdụ. Nchọpụta nsogbu bụ ihe dị oké mkpa na-achọpụta ọrịa kpọmkwem otu ihe na-egosipụta nke a na steeti. Nanị mgbe niile na-achọpụta ọrịa ule na-kenyere a kpọmkwem usoro ọgwụ, nke enyere aka igbochi mmepe nke ọrịa ndị dị ka nke abụọ immunodeficiency.

The ọgwụgwọ maka ọnọdụ a na rụrụ dị na ya ibu na comorbidities.

Na ọnya mkpụrụ ndụ nke monocyte-macrophage mgbagwoju etinyere polioksidony, likopid, molgramostim, filgramostim, buffy uwe.

Ntụpọ na cellular ọgụ achọ polioksidonija, taktivina, tamopina, imunofana, timogena, timolina, myelopid.

Nnọchi ọgwụ na-atụ aro na-anaghị ekwe nke humoral. Tee Sandoglobulin, Octagam, Intraglobin, immunoglobulin biaven, pentaglobin.

Secondary immunodeficiency n'oge ọgwụgwọ n'ụlọ ọgwụ gwọrọ mgbe 20-30 ụbọchị. N'ọdịnihu, ọrịa ga-hụrụ onye dọkịta-ọgụ na ọkachamara nke isi ọrịa. N'oge exacerbation nke ọrịa na-achọ re-omume, n'ihi na nke n'elu formulations na-eji.