The etiology nke sarcoidosis na ihe ọrịa na-mgbagwoju anya na syndrome Lefgrena

Lefgrena syndrome - a symmetrical hilar ọnụ bronchopulmonary lymphatic usoro na abụọ. Ọrịa so site akpụkpọ ngosipụta (erythema nodosum), oké ahụ ọkụ, na arthralgia. Ndị a mgbaàmà ndị e ji mara nke sarcoidosis.

Mgbe ọrịa na-emetụta dị iche iche na akụkụ - akpa ume, splin, Lymph. Lefgrena syndrome sarcoidosis bụghị-ebute site ná ma na ọ bụghị a na-efe efe ọrịa. Ọ bụghị ka e mgbagwoju anya na oncologic ọrịa Filiks na ukwara nta.

adakarị picture

Sarcoidosis kemgbe nnọọ ogologo oge a obere ọrịa, ma taa ọnọdụ agbanweela, daa ọrịa na-agbasa na a ngwa ngwa ọnụego gburugburu ụwa. Dị ka ọnụ ọgụgụ, ihe karịa onye ọ bụla ọzọ na-ata ahụhụ na syndrome Lefgrena inyom site 20 ruo afọ 40, ma ọrịa nwere ike ọ bụla mmadụ.

Ọ nwere ike ime n'enweghị ihe mgbaàmà, nke nta nke nta ma ọ bụ na nnukwu ụdị. Asymptomatic ọgwụ na-emekarị ahụrụ site ohere na mgbochi fluorography nyochaa. Ọtụtụ nkịtị bụ a nwayọọ nwayọọ progression nke ọrịa na ndị na-esonụ ama:

• dyspnea on exertion;
• a dull mgbu na obi;
• mgbu n'etiti ubu pupụtara ;
• akọrọ ụkwara;
• ala-ọkwa fever ;
• ike ọgwụgwụ na adịghị ike;
• oké sweating;
• ọnwụ nke agụụ;
• nkwonkwo mgbu ke ala azụ.

Nnukwu maka sarcoidosis akpọ syndrome Lefgrena, ọ na-esonyere site n'ịzụ okpomọkụ na 38-39 ° C, nkwonkwo mgbu, anụ ọnya n'ụdị erythema, obi mgbu na iku ume ọkụ ọkụ. Ọ bụghị ihe ọhụrụ na nnukwu n'oge full mgbake n'ejighị mmadụ ọgwụgwọ ndị ọzọ adọ.

The etiology nke ọrịa

Ruo mgbe ọgwụgwụ nke na nkà mmụta ọgwụ mara akpata ọrịa a, o yiri ka akpasu ya site na-esonụ ihe ndị nwere ike ịzụlite:

• ọrịa, Mycobacterium ụkwara nta, ịba ọcha n'anya C;
• oghom mpụga ihe, inhaling metal uzuzu;
• ise siga, nke bụ ihe kpatara, kama ukwuu sikwuoro N'ezie nke ọrịa;
• si n'aka ruo n'aka.

Prevention of sarcoidosis

Ọrịa syndrome Lefgrena mkpa ịkwụsị ise sịga, na adị mgbake. Dị Mkpa oge tụlee akụkụ nke obi na 2 afọ. Ewere n'ime akaụntụ eziokwu ahụ bụ na etiology nke ọrịa a na-amaghị ruo mgbe ọgwụgwụ, ụkpụrụ nke mgbochi edinam na-ewepụta. Ọkachamara nwere ike ikwu iji zere kọntaktị na metal ájá na foci nke ibute ọrịa.

Lefgrena syndrome sarcoidosis ahụrụ esonụ extrapulmonary orunótu usoro - imeri subcutaneous anụ ahụ, anụ ahụ na elu Lymph. E nwere onye na-abawanye cervical, subclavian, axillary na inguinal ọnụ. Mgbe ụfọdụ, na-emetụta Lymph nke afo.

Ọkpụkpụ na Central ụjọ usoro na-emetụta ọtụtụ obere ugboro ugboro, ma na-esiri ọrịa ime. Sarcoidosis nke obi na-adị na 20-30% nke ikpe na-asymptomatic. N'aka ekpe nke obi na-ebelata ke olu, nri ventricle abawanye.

Early nnyocha na ọgwụgwọ nyere Ohere na-adabere na a mma pụta. N'ọnọdụ ọzọ, e nwere mgbanwe akpa ume anụ ahụ, nke mechara na-eduga ná nsogbu.

Lefgrena syndrome nnukwu sarcoidosis n'onwe

Ọtụtụ mgbe mgbagwoju anya na sarcoidosis, ụkwara nta n'ihi myirịta nke ihe mgbaàmà. Nke a na-achọ a nyochaa, n'ihi na ndị na-akpata na dị iche iche ọgwụ. Na ọ bụrụ ike ịdị na-eme onwe-ọgwụgwọ, karịsịa ka iji ọgwụ ọjọọ eme zubere maka ọrịa na ụkwara nta, ọ pụrụ iduga ọnwụ.

Lefgrena syndrome (a classic atụ) - nke a bụ mgbe onye ọrịa ahụ n'ozuzu ọnọdụ bụ na-eju afọ ntule. E nwere mgbanwe ndị na-anụ. Ka-egosi:

• papules na mbadamba nkume ndị e;
• Chilblains lupus;
• keloid scars;
• infiltrates;
• erythema nodosum;
• SKD na CKD sarcoid Beck;
• multiple oké ọnụ na subcutaneous anụ ahụ.

nchọpụta nsogbu

Evaluation nke ọrịa Lefgrena syndrome bụ ịrụ X-ray. Ka ukpụhọde usoro eji agbakọrọ tomography. Ẹda Biochemical na ọbara ọnụ.

The nsogbu nke ọgwụgwọ bụ na-ebelata aza. The kasị oru oma ụzọ bụ ojiji nke corticosteroids ruo ọnwa isii. Ọ bụrụ na ọ na-emetụta ndị dị oké mkpa akụkụ a chọrọ glucocorticosteroid hormone ọgwụ.

Ngwa ngwa nwayọọ nwayọọ na-N'ezie-emeso ya na obere ọmụmụ nke igba ogwu n'akwara ochichi nke mgbochi mkpali ọgwụ ọjọọ. N'ọnọdụ ebe ọgwụ bụ-esighị ike, na-enwe plasmapheresis (ọbara ọcha). Mgbe oké ogbo akpa ume na ọrịa na-achọ ngwa transplants. N'ezie nke ọrịa na ọgwụgwọ pụta n'ụzọ dị ukwuu mma, ma ọ bụghị na ọ dị mkpa na-amalite usoro.