Glycosylated haemoglobin na n'ahụ uru

The isi criterion maka ọgwụgwọ nke ọrịa shuga bụ iji nweta a mụ n'ahụ ịta nke sugar (glucose) na ọbara. Ogw sugar nwere ike n'ụlọ iji a obere glucose mita, nakwa dị ka na laabu. Dị ka ihe a otu amụ ịta nke glucose dị n'ọbara bụ ekwe omume na-ekpe ikpe na steeti carbohydrate metabolism ke idem. Ugbu a, mepụtara usoro kpebie ego nke glycosylated haemoglobin nke ohere na-amata ọnọdụ nke carbohydrate metabolism. Ọtụtụ nnyocha mụụrụ DCCT (Diabetes Control Committee na ya na-adakarị nsogbu), ọ hụrụ na ndị glucose larịị ghaghị mekọrịtara na ọrịa ọbara glucose. Glycated haemoglobin - qualitative egosi ịdị irè nke ọgwụgwọ na ọgwụgwọ maka ọrịa nke-arịa ọrịa shuga.

Glycated haemoglobin na-synthesized na mgbakwunye na nke nitrogen hexose ọnụ n'ógbè beta-globin n'agbụ nke haemoglobin A1 klas (HbA1c). Synthesized HbA1c edebe ke mkpụrụ ndụ ọbara uhie (erythrocytes) ma na-ejigide n'ebe a narị na iri na-otu narị na ụbọchị iri atọ (oge nke ndụ nke cell). Dị ka nke a na-egosi, ị nwere ike ikpebi na-larịị nke glucose na-enwe ndidi n'ihi na 2-3 ọnwa tupu ọmụmụ.

Glycosylated haemoglobin, na ya ịta bụ ihe ra nrata nye ego nke glucose dị n'ọbara. Olee otú m nwere ike ikpebi ya larịị ke ọbara? Iji chọpụta nke a oke kacha mma iji pụrụ iche ule na usoro. Ọ dịkwa ike iji ọzọ instrumental na-achọpụta ọrịa ụzọ: gas-mmiri mmiri chromatography na mmekọrita electrophoresis, immunoelectrophoresis, wdg Glycosylated haemoglobin ọnụego ya maka ahụ ike ndị mmadụ bụ n'etiti 4 6%. Ọrịa ọrịa na hyperglycemia glycosylated haemoglobin ụba abụọ ugboro atọ.

Haemoglobin na ụmụ bụ nke otu dị mkpa n'ihi na-eto eto organism metabolism na-budata elu tụnyere ndị okenye. Ya mere, ndị nne na nna kwesịrị maara nke na nyochaa larịị nke haemoglobin n'ime ọbara nke nwa ọhụrụ ha. Nke a dị mkpa iji gbochie ígwè erughi anaemia. Na obi nke mmepe nke a na ọrịa bụ Ferum erughi ke idem, nke a na-ifịk ke njikọ nke haemoglobin. Oxygen ịnọ n'ụkọ njọ na-emetụta mmepe nke ụjọ, dịghịzi na obi usoro. The kasị susceptible ka ígwè erughi anaemia na ụmụ noo 9 ọnwa na 5 afọ.

Ugbu a, ọrịa shuga akara a rụrụ na-enyemaka nke na ụdị ndị Accu-Chek 360 Celsius. Na a ụdị nke onye dibịa-agụta ndị ọrịa glucose ozo na-ebu ọnụ na postprandial. Ndị kasị dị irè ụzọ isi belata ọbara sugar ịta bụ ojiji nke ogologo-eme insulin. Iji Accu-Chek 360 Celsius akwalite kwesịrị ekwesị nhọrọ Usoro insulin. N'ihi ya, anyị belata larịị nke ọbara sugar na nkịtị n'ahụ nso. Ọtụtụ ndị ọkachamara na-arụ ụka na nke a ụdị nke-arịa ọrịa shuga management nwere ike ịdị irè ọnwa ole na ole ka ibelata glycated haemoglobin ise na isii nkeji (n'ahụ norm).

Ya mere ọ bụrụ na ị na a chọpụtara "ọrịa shuga", enwela obi nkoropụ, enye ma na-rapaara na echiche na ndụ bụ ugbua n'elu. N'ihi na ahụ ike ha ga-kwara. Ndị na-arịa ọrịa shuga kwesịrị na-nyochaa ịta nke glucose ke iyịp. Ọ dị nnọọ mfe na-ebu ndị a ọmụmụ ke ufọk karịa na queues ọgwụ. Na ojiji nke oge a na iche-iche nke Accu-Chek 360 Celsius glyukomerov ị nwere ike mfe ịchịkwa ọbara gị sugar etoju.