Sodium hydroxybutyrate

Sodium hydroxybutyrate (gamma-hydroxybutyric acid GHB) bụ hypnotic metabolic edinam. Nke a nkwadebe e ji mee ihe ná Nkụnwụ. Dị ka A. Laborie (French dọkịta na-awa), sodium hydroxybutyrate kwere ka iru a ọhụrụ ịwa ahụ ná Nkụnwụ. The usoro nke edinam nke ọgwụ dabeere na ntụziaka nke cellular metabolism, kama mbibi ya.

Sodium hydroxybutyrate nwere ala intrinsic analgesic ọrụ, Otú ọ dị, ka ikowa mmetụta nke neuroleptics, analgesics na ndị ọzọ na-esi n'aka ná Nkụnwụ.

GHB nwere oké ala toxicity. Nke a bụ eziokwu gbasara ọnọdụ ime-ulo ICU na-arụ ọrụ na-arụ ọrụ, ebe nsogbu nke mmegbu akụkụ okuku ume na center na etiti miorelaxation na elu gabiga ókè doses edozi ọkachamara ngwá maka ventilashion na permeability nke akụkụ okuku ume tract. Community-enwetara n'ikuku GHB e ji ọzọ tiri ibiere toxicity.

Sodium hydroxybutyrate zuru ezu irè ma na igba ogwu n'akwara na na a rectal, onu na intramuscular ngwa. Ndị ngwangwa iwebata na akwara nwere ike ike so muscle twitching convulsive ụdị.

Mgbe ingestion nke GHB gụnyere metabolism kpamkpam. N'ihi ya, ọgwụ na-akadiahade na carbon dioxide na mmiri. Na a obere ego nke mmamịrị mmepụta GHB.

Ngwa nke sodium oxybutyrate ghara ime ka iri mmadụ ahụ na Habituation, na ọ dịghị mmanya ogbugbu. Na iwebata ọgwụ ọrịa dara n'ụra mma na mfe, na-ehi ụra na-atụle ga-enye ume ọhụrụ, elu-ọkwa.

Agwọ ọrịa dị iche ogo curvature "dose-mmetụta" (ibawanye onunu ogwu na-eduga onye na-abawanye na mmetụta ugboro anọ). Na ọgwụgwọ ichekwa fọrọ nke nta dịghị inhibitory utịp ke akụkụ okuku ume na center.

GHB a na-ewere ihe ndị kasị nwere ike stimulator nke pituitary gland nke niile mara. Ịnata (otu ugboro), sochiri nkenke (ruo ọtụtụ awa) ụba ịta nke ibu hormone na a iri na iri na iri na ise ugboro.

Iji sodium Oskibutirata akwalite abawanye nke ventricular fibrillation mbata.

GHB anabolics na-ezo aka kpọmkwem ihe. The ọgwụ nwere ike n'ọrụ na parenteral oriri na-edozi, n'ihi na ọ na-akpata a gụnyere ya ná protein mmebi. Dị mkpa maka a na-atụle Dosages nke 8-12 grams kwa ụbọchị.

GHB nwere ikike na a ịrịba Mbelata cholesterol ịta na ọbara. The agwọ ọrịa bụ a nwere ike antihypoxant (gị n'ụlọnga enwekwu ndị na-eguzogide nke organism na oxygen erughi), radioprotector. The ọgwụ na-eme ka a dị ịrịba ama ike nke mesenteric ọbara eruba na mmepe nke hypothermia.

Ụfọdụ n'ime Njirimara depụtara n'elu mere ka eziokwu ahụ bụ na GHB otu oge ọtụtụ-eji a ndu nwekwara (nri). Ọ na-na a ike, ọgwụ nwere ike zụrụ nnọọ kpam kpam na-enweghị ọgwụ na Western Europe na America. Otú ọ dị, n'ihi na eziokwu na mgbe a ụfọdụ oge nke GHB malitere ga-eji dị ka a psychotropic gị n'ụlọnga si free ire napụrụ. Ọzọkwa, nke na-abụghị ike ojiji nke ọgwụ sodium hydroxybutyrate, n'ichepụta na nnukwu mpịakọta, na-enye maka mpụ ibu.

An ovadozu ọgwụ na-abịa ngwa ngwa. Ka ihe atụ, ihe ọzọ akụkụ anọ grams kama anuri akpalite retching. The Nchikota GHB na ndị ọzọ na umi nwere ike ime ka dị oké njọ.

Sodium hydroxybutyrate. ntụziaka

Maka igba ogwu n'akwara excitable na ike (ikpọkidem) ọrịa onunu ogwu ngụkọta oge na-mere dabere na ahu aro (70-120 grams kwa kilogram). Narcosis emee anọ na isii nkeji mgbe ngwa, mgbe nke ọzọ ná Nkụnwụ na-emiwanye emi 40 g / n'arọ.