Urea. Norma na-akpata deviations.

Urea bụ a protein decomposition ngwaahịa. Mgbe mmeghachi omume deamination nke amino asịd na-emepụta amonia. Iji belata ya toxicity na neutralize, na-synthesized na imeju urea. Urea - a ala molekụla ibu compound, kpam-agafe cell membranes nke mkpụrụ ndụ ọbara uhie na parenchymal akụkụ. N'agbanyeghị eziokwu na urea onwe ya bụ ala-na-na-egbu egbu, na-egbu egbu ma potassium ion na-akpọkọtara na ya, na guanidine emepụta. Ọ bụ ya mere na ahụ mmadụ dị mkpa iji na-na-adịgide adịgide nọgidere na-enwe dị mkpa larịị nke urea. The norm nke ọdịnaya na-adabere na afọ nke onye, na ọ nwere ike na-egosi na analysis.

Urea - a osmotic ifịk umi, otú ya oké ìgwè pụrụ iduga ọzịza nke anụ ahụ nke parenchymal akụkụ, Central ụjọ usoro, subcutaneous anụ ahụ nke myocardium.

Iji chọpụta otú ihe n'ụzọ dị irè na ngwaọrụ na-arụ ọrụ glomerular akụrụ, ọ nwere ike na-amụ larịị, agaghi asu plasma lekwasị urea. The norm nke ya ọdịnaya na ọbara kwesịrị 1,8-7,5 mmol / l. N'otu oge ahụ nke kasị ala ọnụego nwere ike ahụkarị ụmụ n'okpuru afọ 14 afọ, na kasị elu - maka ndị agadi, onye afọ esịmde isua 60. Na ụmụ ọhụrụ a index ga n'ozuzu-erughị 4.3 na ihe na-erughị 1.4 mmol / l.

Iji chọpụta ịta nke urea eme Biochemical analysis of ọbara. N'ihi na a zuru ezu karị, picture, tinyere urea nwekwara ike kpebisie ike na ọdịnaya nke creatine. Ọ bụrụ na, na-arụpụta nke nyochara, urea e mụbara, mgbe ahụ, a ọnọdụ a na-akpọ uremia. Ọtụtụ mgbe ọ na-esonyere a clinically iche syndrome nke igbu egbu. Urea na-emepụta na ụba ichekwa n'oge catabolic-ekwu, na oké ojiji nke protein, na assimilation nke na-edozi na amino asịd mgbe gastric ọbara ọgbụgba. The plasma ịta nke urea na-abawanye dị ka a n'ihi nke akpịrị ịkpọ nkụ n'ihi ubara n'ezinụlọ absorption na akụrụ tubules. Ụfọdụ n'ime ọrịa na-eduga ụba etoju nke urea, nwere ike depụtara dị ka ndị a:

• Amyloidosis, gbasara akụrụ, pyelonephritis, glomerulonephritis, ụkwara nta akụrụ ;
• Ndiiche mmamịrị eruba ma ọ bụ ogbenye patency nke urinary tract;
• Ịza aza etuto ahụ na-arịa ọrịa leukemia;
• Heart ọdịda;
• agba ọbara;
• Myocardial infarction;
• bowel mgbochi;
• ahụ ọkụ;
• Burns, ma ọ bụ ujo;
• akpịrị ịkpọ nkụ;
• cachexia;

E nwekwara a n'ahụ ọnọdụ, mgbe ọnụego na-abawanye, nke na-lekwasị n'ime ọbara urea. Ahụkarị ya chọrọ larịị nwere ike karịa ka a N'ihi nke mgbe ikike mmega.

Dịkwuo urea ọdịnaya na nwere ike iji ọgwụ ụfọdụ. Otu n'ime ha nwere ike kwuru dị ka phenylbutazone, anabolic Steroid, aldomet, dopegit, Rauwolfia alkaloids, ígwè preparations, na nephrotoxic ọgwụ ọjọọ.

N'ihi ya, ọbara ule nwere ike chọpụtara na urea na-ebelata. Otú ọ dị, nke a mere nnọọ adịkarịghị. Na nke a emee Ọtụtụ ikpe ebe ndị mebiri nke sịntetik ọrụ nke imeju, na ọ bụrụ na onye ọrịa na-erepịakwa a obere ego nke protein. Akpasu a ọnụ ke ọbara urea etoju nwere ike ọrịa ndị dị ka imeju, ịba ọcha n'anya na hepatic Coma, hyperhydration, acromegaly, nsi site arsenic ma ọ bụ site, nakwa dị ka ala mgbe dialysis. Mgbe n'ahụ ozo nwere ike belata n'oge ime urea. Ahụkarị ya ịta n'ime ọbara n'oge a na-ukwuu belata. Ihe kpatara nke mbenata urea nwekwara ike ịbụ a na-eri ma ọ bụ agụụ. Ọ bụ ya mere i kwesịrị nri obibia nri.