Beta blockers

Ọgwụ ndị na-abụ otu a nke bekee ji na-emeso ndị kpatara ọrịa obi: ịrịa ọrịa obi (gụnyere nnukwu myocardial infarction, prophylaxis nke rịaworo pectoris), ọbara mgbali elu, tachyarrhythmias, ala ala obi ọdịda.

Beta blockers eme ihe dị ka asọmpi na-akụ ọkpọ nke noradrenaline, adrenaline na ndị ọzọ na bekee nwere Njirimara nke beta adrenoceptor agonists on.

Nrụpụta ọrụ nke ogige ke otu a na-adabere na ala nke ọmịiko ụjọ usoro. Na onye na-abawanye nke usoro ihe a, na-arụpụta bekee mee ahụ mmadụ. Na Anglịkan. Karịsịa, ịdị irè ha enwekwu na dị iche iche pathologies nke obi, nke na-ebu na-akpata nchekasị ọnọdụ, thyrotoxicosis, na-ese siga (nicotine abawanye ọmịiko ụda).

Ọgwụ bekee nyere pharmacological iche iche bụ nke atọ ụdị: a mbuaha, na-abụghị nhọrọ na nhọrọ. Beta blockers: atenolol, metoprolol, acebutolol, bisoprolol, esmolol - nwe-atọ ụdị. Non-nhọrọ ọgwụ ọjọọ na-anọchite anya propranolol, nadolol, pindolol, penbutalolom, timolol, oxprenolol, sotalol. Ịgwakọta blockers: labetalol, carvedilol.

ngwa

The isi gbasara obi daa ọrịa, nke na-eji beta blockers - ischemic ọrịa obi. The usoro nke ihe nke bekee bụ a beta adrenergic mgbochi, na-eduga a ọnụ nke obi ọrụ: contractility, conduction, excitability, automatism. N'ihi bụ a Mbelata nke obi, nke bụ a ọnụ ke obi ọnụego, ọrịa strok olu na gbasara obi mmepụta. Myocardial oxygen ina na-ukwuu belata, ma si otú ana achi achi irè mgbochi nke rịaworo ọgụ. Ọgwụ ọjọọ nke otu a na-ebelata ihe ize ndụ nke ọnwụ mberede na ọrịa ndị na-ahụhụ myocardial infarction.

N'ihi cupping tachyarrhythmias na-eji beta adrenoblokatorry. The ọnụ ke obi ọnụego, ibelata nke atrioventricular conduction akọwa ọgwụgwọ mmetụta. A ọzọ akpọ mmetụta nke ọgwụ ọjọọ a hụrụ na ọnụnọ nke atrial arrhythmias.

Ọgwụ bekee nke nwere beta igbochi edinam nke otu n'ime ise klas nke antihypertensive mmadụ. Ha na-eji na-emeso ọ bụla na ogbo nke ọbara mgbali elu, dị ka nke ọma dị ka maka ọgwụgwọ nke symptomatic ụdị ọrịa ahụ. The usoro nke ihe nke beta blockers mee nke anọ mmiri: belata n'obi ọrụ, suppression nke renin-angiotensin usoro, ẹsụhọde ụda ndị vasomotor center, mbenata ngụkọta elu-eguzogide ọbara.

Maka ọgwụgwọ nke ala ala obi odida blockers na-eji. Otu a ọgwụ ọjọọ eme ihe a na-ewepụ oké mmetụta nke ọmịiko ụjọ usoro n'obi. Nke a na-ebelata ihe oghom mmetụta nke epinephrine na nọrepinefrini na obi, mbelata ọrụ nke beta adrenergic anabata, ibelata obi ọnụego. Otú ọ dị, ojiji nke oké doses nke ọgwụ ọjọọ nwere ike ibu na data obi ọdịda.

Beta blockers na-eji ihe n'ụzọ dị irè maka ọgwụgwọ nke na-emeghe-n'akuku glaucoma. Ha na-enyere belata ọmụmụ secretion nke ciliary ahu. N'ihi ya, kpukpru usen nke intraocular nsogbu na ọrịa mgbaàmà akwụsị.

Maka ọgwụgwọ nke migraine ọgụ eji metoprolol, atenolol, timolol na nadolol. Ha edinam na-kọwara a spasm nke ụbụrụ arịa, ọgwụ ọjọọ agonistic ọrụ na serotonin anabata na Central ụjọ usoro.